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How Long Does Suboxone Stay In Your System? Useful Tips You Should Know

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The main thing to note is that buprenorphine and naloxone, which together make up Suboxone, each have a different half-life. The half-life of a medication is how long it takes for half of a single dose to leave your body.

Suboxone How Long Does It Stay In Your System?

For up to two weeks following the last dose, suboxone can still be found in urine. This is affected by various variables, but half-life has the most significant impact. Many ask, how long does suboxone stay in your system? The main thing to note is that buprenorphine and naloxone, which together make up Suboxone, each have a different half-life. The half-life of a medication is how long it takes for half of a single dose to leave your body. An average medicine has five half-lives before it entirely leaves your body.

You may have received a methadone or Suboxone prescription as part of your treatment plan if you or someone you know is seeking help for an opioid addiction. Both are essential components of medication-assisted therapy, a method for treating people who have opioid dependency or addiction.

How Long Do Suboxone Stay In Your System?

Suboxone users frequently ask about how long suboxone stay in your system. The drug’s half-life is a primary factor in how long will suboxone stay in your system. Other factors also have a role.

Buprenorphine, the primary component of Suboxone, has a particularly lengthy half-life of elimination compared to other opioids. The time it takes for a drug’s elimination half-life to occur is measured in hours. how long does suboxone stay in your system 8mg? It has a half-life of 24 to 42 hours.

Buprenorphine is converted into norbuprenorphine once your body breaks it down. Compared to buprenorphine, this drug has a half-life of up to 150 hours. Furthermore, norbuprenorphine has a 14-day half-life in urine.

Half of the buprenorphine in a Suboxone dose is eliminated by the body in almost two full days. How long suboxone stay in system? A single dose of Suboxone may take nearly nine days to leave your body because it takes five half-lives for a drug to go through your system entirely.

The other component of Suboxone, naloxone, has a half-life of 2 to 12 hours. Your body can then keep it for up to 60 hours. Doctors rarely check for naloxone exposure because the medication is not abused.

Buprenorphine, the opioid in Suboxone, was developed in the 1970s as a safer opioid than morphine or heroin for pain treatment. Studies suggested that buprenorphine could be an attractive alternative to methadone, as it could require fewer regulations because of its inherent abuse deterrence properties as a partial opioid agonist-antagonist. The drug’s manufacturer and the addiction treatment community lobbied for an exception to the Narcotic Addict Treatment Act to allow individual providers, rather than federally designated clinics, to prescribe buprenorphine. The Drug Addiction Treatment Act of 2000 authorized physicians via a new individual waiver to prescribe specific opioids to treat opioid use disorder. Buprenorphine is currently the only opioid authorized under this waiver. [1]

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Suboxone Drug Facts


Suboxone contains a combination of buprenorphine and naloxone. Buprenorphine is an opioid medication, sometimes called a narcotic. Naloxone blocks the effects of opioid medication, including pain relief or feelings of well-being that can lead to opioid abuse.

Alternatives to Suboxone

  • Lofexidine
  • Methadone
  • Naltrexone

Common Side Effects

  • Nausea and vomiting
  • Headache
  • Sweating
  • Numb mouth
  • Constipation
  • Painful tongue
  • Dizziness and fainting
  • Problems with concentration
  • Irregular heartbeat
  • Insomnia
  • Blurry vision
  • Back pain
  • Drowsiness

Other Less Common Side Effects:

  • Anxiety
  • Depression
  • Nervousness


Suboxone can slow or stop your breathing and may be habit-forming. Misuse of this medicine can cause addiction, overdose, or death, especially in a child or other person using the medicine without a prescription.

Taking Suboxone during pregnancy may cause life-threatening withdrawal symptoms in the newborn.

Fatal side effects can occur if you use this medicine with alcohol or with other drugs that cause drowsiness or slow your breathing.

Suboxone Statistics

Opioid addiction rates are at an all-time high. In 2014, 4.3 million people abused prescription opioids, and 1.9 million had an opioid use disorder related to prescription pain relievers.

4.3 million

4.3 million people abused prescription opioids.

Source: NIH

1.9 million

1.9 million had an opioid use disorder related to prescription pain relievers

Source: NIH

Most physicians, addiction experts, and advocates agree that Suboxone saves lives. The U.S. Government has recently been lightening up on the requirements needed for doctors and nurses to “get waivered” in an urgent attempt to increase the availability of Suboxone prescribers, as the number of opioid deaths keeps rising.

All opioids are chemically related and interact with opioid receptors on the body and brain nerve cells. Opioid pain relievers are generally safe when taken for a short time and as prescribed by a doctor, but because they produce euphoria in addition to pain relief, they can be misused (taken in a different way or a larger quantity than prescribed or taken without a doctor’s prescription). Even as prescribed by a doctor, regular use can lead to dependence, and when misused, opioid pain relievers can lead to addiction, overdose incidents, and deaths.

An opioid overdose can be reversed with the drug naloxone when given right away. Improvements have been seen in some regions of the country by decreasing the availability of prescription opioid pain relievers and decreasing misuse among the nation’s teens. However, since 2011, overdose deaths involving heroin have increased dramatically. Fortunately, effective medications exist to treat opioid use disorders, including methadone, buprenorphine, and naltrexone.

While Suboxone can be an effective drug to aid in recovery from opiate dependence, it is often a drug that is taken for long periods after the user has stopped taking other addictive opioids. Despite its effectiveness, Suboxone can also be addictive. As a partial opioid agonist, Suboxone produces similar withdrawal effects to other opioids if it is quit “cold turkey.”

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Factors that Influence How Long Suboxone Stay System

How long does suboxone stay in your system?Suboxone typically needs nine days to leave a person’s system altogether. The medicine may leave the bloodstream more quickly for some people while taking longer than usual for others. The following are a few factors that could affect how many days does suboxone stay in your system:

  • Liver Function: Individuals with impaired liver function may have higher blood levels of Suboxone than those with healthy livers. Furthermore, those with liver issues may experience a longer half-life of Suboxone.
  • Dosage: The faster Suboxone is eliminated from the body, the lower the dose.
  • Frequency of Use: Due to frequent use, regular Suboxone users may have some drug buildup in their bodies. Because of this, someone who routinely takes it may require more time to eliminate it from their system than someone who has only taken it once.
  • Co-ingestion with Other Drugs: Some drugs can make Suboxone more concentrated in your body, making it take longer to leave your system. Atazanavir, an HIV treatment included in medications like Evotaz and Reyataz, is one of these medications.
How long does suboxone stay in your system for? Suboxone typically needs nine days to leave a person's system altogether. having trouble with suboxone? Get the best suboxone treatment at We Level Up NJ
How long does suboxone stay in your system for? Suboxone typically needs nine days to leave a person’s system altogether. having trouble with suboxone? Get the best suboxone treatment at We Level Up NJ

Suboxone is a prescription drug used as part of an opioid treatment program that includes behavioral therapy and counseling. Suboxone, which contains buprenorphine and naloxone, can be an effective medication for opiate dependence. Still, sometimes, it must be taken for long periods after the user has stopped using addictive opioids. Despite its effectiveness, Suboxone can also be addictive, and it produces similar withdrawal effects to other opioids if it is quit “cold turkey.” Symptoms of withdrawal from Suboxone can include:

  • Nausea and vomiting
  • Muscle and body aches
  • Anxiety, depression, and irritability
  • Fever or chills
  • Sweating and Headaches

The symptoms can vary in severity and duration, depending on how long users have been taking Suboxone, as well as the dosage of the drug. Generally, most physical withdrawal symptoms will subside after one month, though psychological dependence can remain. Suboxone Withdrawal Symptoms are the worst in the first 72 hours. This is when most physical symptoms are experienced. Then, in the first week after discontinuation of Suboxone, symptoms generally subside to general aches and pains in the body, as well as insomnia and mood swings.

After the second week, depression is the biggest symptom. After one month, users will likely still be experiencing intense cravings and depression. This is the most delicate time after stopping Suboxone use, as users have a great potential for relapse. If you or a loved one is suffering from addiction to suboxone, please seek help immediately from a treatment professional. Like any other addictive substance, withdrawal from Suboxone can last several months. Though the significant physical symptoms will cease after a month of not taking the drug, psychological symptoms can go on for several months.

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How long does suboxone stay in your system? It can last for up to 9 days. Also, depending on the test, it can be detected for about 3 months.
How long does suboxone stay in your system? It can last for up to 9 days. Also, depending on the test, it can be detected for about 3 months.

How Long Does Suboxone Stay in System? Detection in Drug Tests

Suboxone can be found using a variety of drug tests. Suboxone won’t cause a false positive for other opioids, despite popular belief to the contrary.

Detecting morphine is a standard method used in routine urine tests to check for the presence of opioids. Numerous opioids, including heroin, convert into morphine, which is why they are found in urine screening tests. Special tests are required to find opioids like Suboxone, which do not metabolize into morphine.

Suboxone can commonly come in the form of tablets or films/strips. With that said, how long does a suboxone strip stay in your system? Or how long do suboxone strips stay in your system? Suboxone can be found in hair. A 1.5-inch hair sample often reveals the past 90 days of drug use. Additionally, for around five days after the last dose and about 96 hours after that, doctors can detect Suboxone in plasma and saliva. Lastly, it can be seen in urine for about 2 weeks.

Blood tests are invasive yet have a narrow window for detecting buprenorphine. They can see drugs immediately after intake. So, how long does suboxone stay in your system? Over 2 hours after the last dose is when a blood test will function the best. Saliva tests are increasingly frequently used since they are straightforward and noninvasive. After the previous Suboxone dose, these tests may continue to be effective for a few days or even longer.

Although suboxone addiction is less frequent than other addiction problems, it is nonetheless an opioid issue. Many specialized centers can treat this form of the condition and assist those affected in avoiding the numerous problems connected to long-term opiate usage. It is preferable to seek medical guidance and go off the Suboxone dosage under medical supervision rather than stopping abruptly if an addiction is detected.

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Suboxone Treatment

Suboxone treatment can help with withdrawal symptoms during a detox program, but it shouldn’t be the only treatment option. Suboxone should be combined with counseling, support groups, and other techniques that a treatment program finds essential. Only use Suboxone in the prescribed dosage and manner. Abuse of it may result in adverse side effects or dependence.

The following buprenorphine products are FDA approved for the treatment of OUD:

  • Generic Buprenorphine/naloxone sublingual tablets
  • Buprenorphine sublingual tablets (Subutex)
  • Buprenorphine/naloxone sublingual films (Suboxone)
  • Buprenorphine/naloxone) sublingual tablets (Zubsolv)
  • Buprenorphine/naloxone buccal film (Bunavail)
  • Buprenorphine implants (Probuphine)
  • Buprenorphine extended-release injection (Sublocade)

Medication-assisted treatment is a comprehensive approach that combines approved medications (currently, methadone, buprenorphine, or naltrexone) with counseling and other behavioral therapies to treat patients with OUD. Regular adherence to MAT with buprenorphine reduces opioid withdrawal symptoms and the desire to use opioids without causing the cycle of highs and lows associated with opioid misuse or abuse. At proper doses, buprenorphine also decreases the pleasurable effects of other opioids, making continued opioid abuse less attractive. According to the Substance Abuse and Mental Health Services Administration, patients receiving MAT for their OUD cut their risk of death from all causes in half.

The combination of Naloxone and Buprenorphine is designed to reduce drug cravings and prevent withdrawal symptoms associated with opioid addiction. When used with the right guidance, Suboxone is proven effective in treating opioid misuse. Being a schedule three substance, Suboxone can cause drug dependence when used long-term. Physical dependence can cause Suboxone withdrawal symptoms if patients go cold turkey or abruptly stop using the medication.

To prevent these mental and physical withdrawal symptoms, the suboxone treatment dosage should gradually decrease should the client wish to be off the medication. If a patient thinks they might have developed an addiction to Suboxone, they must reach out to a medical professional or connect to a detoxing center. To reiterate, Suboxone treatment can be addictive and should always be administered by specially trained medical personnel.

Call our substance abuse professionals to discuss your detox programs if you or someone you care about has been struggling with drug addiction or other addiction problems.

Drug addiction and mental health treatment use a dual-diagnosis approach. While one treatment program may treat unresolved trauma, unconscious conflicts, and individual issues, group sessions usually incorporate teaching life skills, stress management, and social relationships. Additionally, the therapy enables patients to share their thoughts and experiences with others to create the emotional relationships required for a complete recovery.

Detoxing without medical supervision can be painful and difficult, so avoid attempting it yourself. Take immediate action if you or someone you care about consistently exceeds these suggested daily limits or demonstrates signs of alcohol withdrawal. At We Level Up NJ, addiction specialists are ready to help.

At We Level Up NJ, you can experience the best suboxone treatment suited to your needs.
At We Level Up NJ, you can experience the best suboxone treatment suited to your needs.

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How long does suboxone strips stay in your system? And how long does suboxone strip stay in your system?

Suboxone can typically come in the form of strips and pills. In urine, suboxone usually lasts for 2 weeks.

How long does a suboxone stay in your system?

When tested using urine, suboxone can be detected for up to 14 days.

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  2. ARUP Laboratories. “Drug Plasma Half-Life and Urine Detection Window.” January 2019. Accessed June 21, 2020.
  3. Hallare, Jericho; Gerriets, Valerie. “Half Life.” StatPearls, January 30, 2020. Accessed June 21, 2020.
  4. Smith, Kevin; Hopp, Michael; Mundin, Gill; et al. “Low Absolute Bioavailability of Oral Nal[…] in Healthy Subjects.” International Journal of Clinical Pharmacology and Therapeutics, 2012. Accessed June 21, 2020.
  5. Gryczynski J, Schwartz RP, Mitchell SG, et al. “Hair Drug Testing Results and Self-repor[…]isk Illicit Drug Use.” Drug and Alcohol Dependence, May 17, 2014. Accessed June 21, 2020.
  6. Belivanis, Stamatis; Tzatzarakis, Manolis n; Vakonaki, Elena; et al. “Buprenorphine and Nor-Buprenorphine Leve[…]Suboxone Treatment.” Drug Testing and Analysis, 2014. Accessed June 21, 2020.