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What is the M367 Pill?

The pill with the imprint M367 is white and capsule-shaped, containing Acetaminophen and Hydrocodone Bitartrate.

It contains both an opioid (hydrocodone) and a non-opioid pain reliever (acetaminophen). Hydrocodone alters how your body feels and responds to pain in the brain. Acetaminophen can also be used to treat fevers. Acetaminophen/hydrocodone belongs to the drug class narcotic painkiller combinations and is used to treat back pain, pain, and cough. During pregnancy, no risk can be ruled out. This medication is used to treat moderate to severe pain.

Why Is M367 Pill Prescribed?

Hydrocodone is prescribed to treat severe pain. Hydrocodone is only prescribed to people who are expected to require medication to relieve severe pain around-the-clock for an extended period and who cannot be treated with other medicines or treatments. Extended-release (long-acting) hydrocodone capsules or tablets should not be used to treat pain that can be controlled with as-needed medication. Hydrocodone belongs to the class of opiate (narcotic) analgesics. It works by altering how the brain and nervous system react to pain.

This monograph only covers the use of hydrocodone on its own. If you are taking a hydrocodone combination product, read the hydrocodone-combination monograph and ask your doctor or pharmacist for more information.

How Does M367 White Oval Pill Work?

Norco (hydrocodone/acetaminophen) is a pain medication combination that treats moderate to severe pain. Hydrocodone is an opioid that suppresses pain signals in the brain and spinal cord. Acetaminophen, also known as Tylenol, is a non-opioid pain reliever that inhibits the production of specific chemicals in the brain.

As directed by your doctor, take this medication by mouth. You can take this medication with or without food. If you have nausea, taking this medication with food may help. Inquire with your doctor or pharmacist about other ways to reduce nausea (such as lying down for 1 to 2 hours with as little head movement as possible). If taking this medication in liquid form, measure the prescribed dose using a measuring device. If you use a regular spoon, you may not get the correct amount.

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M367 White Pill Side Effects

Lightheadedness, dizziness, sedation, nausea, and vomiting are the most commonly reported adverse reactions. These effects appear to be more pronounced in ambulatory patients than in nonambulatory patients, and some of these adverse reactions may be alleviated if the patient lies down.

Other side effects include:

Central Nervous System: Drowsiness, mental clouding, lethargy, impairment of mental and physical performance, anxiety, fear, dysphoria, psychic dependence, and mood changes are all symptoms of a malfunctioning central nervous system.

Gastrointestinal System:  Prolonged administration of hydrocodone bitartrate and acetaminophen tablets may result in constipation.

Genitourinary System: Ureteral spasm, vesical sphincter spasm, and urinary retention have all been reported as side effects of opiates.

Respiratory Depression: By acting directly on the brain stem respiratory center, hydrocodone bitartrate may cause dose-related respiratory depression.

Special Senses: Cases of hearing impairment or permanent loss have been reported primarily in chronic overdose patients.

Dermatology – Skin rash and pruritus

Oval White Pill M367 Fact Sheet

M367 (Hydrocodone and Acetaminophen)

A strong prescription pain medicine containing an opioid (narcotic) that is used to manage pain severe enough to necessitate the use of an opioid pain medicine when other pain treatments, such as non-opioid pain medications, do not adequately treat your pain or you are unable to tolerate them.

An opioid pain reliever that can lead to overdose and death. Even if you take your medication exactly as prescribed, you are vulnerable to opioid addiction, abuse, and misuse, which can lead to death.

Adverse Effects

Common side effects of the hydrocodone-acetaminophen medication include constipation, dizziness, nausea, vomiting, drowsiness, and respiratory depression. In addition, there have been reports of progressive sensorineural hearing loss associated with chronic hydrocodone/acetaminophen use that is resistant to high-dose steroids but responsive to cochlear implantation.

As with all opioids, tolerance leading to ever-increasing doses of opioids to maintain the same level of pain control and physical dependence is the most common side effect. Furthermore, acute and chronic opioid administration can suppress antibody and cellular immune responses, as well as natural killer cell activity, cytokine expression, and phagocytic activity. As a result, opioid implications point to an increased incidence of infections in heroin users.


Vyvanse is classified as a Schedule II controlled substance. Schedule II drugs, substances, or chemicals are defined as drugs with a high potential for abuse.

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Symptoms of M367 White Pills Overdose

Toxicity from hydrocodone or acetaminophen may occur after an acute overdose.

Hydrocodone – Hydrocodone overdose is characterized by respiratory depression (a decrease in respiratory rate and tidal volume, Cheyne-Stokes respiration, cyanosis), extreme somnolence progressing to stupor or coma, skeletal muscle flaccidity, cold and clammy skin, and occasionally bradycardia and hypotension. Severe overdosage can result in apnea, circulatory collapse, cardiac arrest, and death.

Acetaminophen: The most severe adverse effect of acetaminophen overdosage is dose-dependent, potentially fatal hepatic necrosis. Renal tubular necrosis, hypoglycemic coma, and coagulation defects are all possible complications.

Nausea, vomiting, diaphoresis, and general malaise are common early symptoms of a potentially hepatotoxic overdose. However, hepatic toxicity may not be evident clinically or in the laboratory until 48 to 72 hours after ingestion.

M367 Pills Interactions

Drug interactions can alter the way your medications work or put you at risk for serious side effects. This document does not include every possible drug interaction. Maintain a list of all your products (including prescription and nonprescription drugs and herbal supplements) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medications without first consulting your doctor.

Certain pain medications (mixed opioid agonists/antagonists such as butorphanol, nalbuphine, and pentazocine), naltrexone, and semi orphan may interact with this drug.

Suppose this medication is combined with other medicines that cause drowsiness or breathing problems. In that case, the risk of serious side effects (such as slow/shallow breathing or severe drowsiness/dizziness) may be increased. Tell your doctor or pharmacist if you are taking any other medications, including opioid pain relievers (codeine, oxycodone), alcohol, marijuana (cannabis), sleep or anxiety medications (alprazolam, lorazepam, zolpidem), muscle relaxants (carisoprodol, cyclobenzaprine), or antihistamines (such as cetirizine, diphenhydramine).

What is the M367 Pill? It is a pain medication combination that treats moderate to severe pain. Hydrocodone is an opioid that suppresses pain signals in the brain and spinal cord. Acetaminophen, also known as Tylenol, is a non-opioid pain reliever that inhibits the production of specific chemicals in the brain.
What is the M367 Pill? It is a pain medication combination that treats moderate to severe pain. Hydrocodone is an opioid that suppresses pain signals in the brain and spinal cord. Acetaminophen, also known as Tylenol, is a non-opioid pain reliever that inhibits the production of specific chemicals in the brain.

Check the labels of all your medications (such as allergy or cough-and-cold remedies) because they may contain drowsy ingredients. Then, inquire with your pharmacist about how to use those products safely.

Other medications can interfere with removing hydrocodone/acetaminophen from your body, affecting how well it works. Among these are azole antifungals (such as ketoconazole), macrolide antibiotics (such as erythromycin), levoketoconazole, mifepristone, HIV medications (such as tipranavir), rifamycins (such as rifabutin, rifampin), ritonavir, and certain seizure medications (such as carbamazepine, phenytoin).

This medication may cause false results in specific lab tests (such as amylase/lipase levels). Therefore, make sure lab personnel and your doctors know you are taking this medication.

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What Special Precautions Should I Follow When Taking M367 Pill?

If you are allergic to hydrocodone, the other medication in the hydrocodone combination product you are taking, other opiate (narcotic) medications such as morphine or codeine, any other medications, or any of the ingredients in the hydrocodone combination product you are taking, tell your doctor and pharmacist. For a list of the ingredients, consult your pharmacist or the manufacturer’s information for the patient.

What Special Dietary Instructions Should I Follow Taking White M367 Pill?

Continue to eat generally unless your doctor tells you otherwise.

What Should I Do if I Forget A Dose of the M367 Pill?

This medication is typically taken only when necessary. If your doctor has prescribed a hydrocodone combination product, take the missed dose as soon as you remember. Wait at least 4 hours before taking the following tablets, syrup, capsule, or solution, or at least 12 hours before taking the next dose of extended-release capsules or extended-release solution. If your next dose is approaching, skip the missed dose and resume your regular dosing schedule. Do not double the amount to make up for a missed one.

What Side Effects Can M367 Pill Cause?

Hydrocodone combination products may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

  • constipation
  • drowsiness
  • lightheadedness
  • hazy thinking
  • anxiety
  • atypically happy or atypically sad mood
  • throat irritation
  • urinating difficulties
  • rash
  • itching
  • pupils constriction (black circles in the center of the eyes)
What Should I Know About Storage And Disposal Of A M367 Pill On it?

Keep this medication in its original container, tightly closed, and out of the reach of children. Keep it at room temperature and away from sources of extreme heat and moisture (not in the bathroom). Any outdated or no longer needed medication must be disposed of immediately through a medicine take-back program. If you do not have a nearby or readily accessible take-back program, flush any outdated or no longer needed hydrocodone combination products down the toilet so that others do not take them. Consult your pharmacist about how to dispose of your medication correctly.

Keeping all medication out of children’s sight and reach is critical because many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and are easily opened by young children. To keep young children safe from poisoning, always lock the safety caps and immediately place the medication in a secure location out of their sight and reach.

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M367 Pill Treatment

A single or multiple drug overdose involving hydrocodone and acetaminophen is considered a potentially lethal polydrug overdose, and consultation with a regional poison control center is advised.

Immediate treatment includes cardiorespiratory support and drug absorption reduction measures. Oxygen, intravenous fluids, vasopressors, and other supportive measures should be administered as needed. Ventilation that is assisted or controlled should also be considered.

In the case of a hydrocodone overdose, the priority should be to reestablish adequate respiratory exchange by providing a patent airway and instituting assisted or controlled ventilation. Naloxone hydrochloride, a narcotic antagonist, is a specific antidote for respiratory depression caused by overdosage or unusual sensitivity to narcotics such as hydrocodone. Because hydrocodone has a longer duration of action than the antagonist, the patient should be monitored closely and repeated doses of the antagonist should be given as needed to maintain adequate respiration. Without clinically significant respiratory or cardiovascular depression, a narcotic antagonist should not be administered.

Suppose acetaminophen ingestion is known or suspected to have occurred within a few hours of presentation. In that case, gastric decontamination with activated charcoal should be administered just before N-acetylcysteine (NAC) to reduce systemic absorption.

To assess the potential risk of hepatotoxicity, serum acetaminophen levels should be obtained immediately if the patient presents 4 hours or more after ingestion; acetaminophen levels drawn less than 4 hours after ingestion may be misleading. NAC should be administered as soon as possible where the impending or evolving liver injury is suspected of achieving the best possible outcome. When oral administration is not likely, intravenous NAC can be used.

Severe intoxication necessitates aggressive supportive therapy. Because the hepatic injury is dose-dependent and occurs early in intoxication, procedures to limit the drug’s continued absorption must be readily available.

Find The Right M367 Pill Addiction Treatment at We Level Up NJ

Detoxing in a rehab center where you can access experienced professionals who can manage alcohol detox and withdrawal complications is advisable.  The medically supervised detox processes allow the body to process the alcohol in the system and gently enable the body to be unaccustomed to its dependence.  It is the first stage of alcohol treatment and one you should seek before your addiction gets more acute.

In conclusion, those suffering from addiction for long periods at high use rates usually encounter more severe withdrawal symptoms, making the process more difficult.  Also, the symptoms may seem to get worse through the detox process.  They need constant care and attention to help manage the symptoms. Detoxing from alcohol and addiction treatment is within your reach to ensure your recovery starts on a healthy and safe step.

Contact us today at We Level Up New Jersey if you, your friend, or your family need help with alcoholism.

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[1] NIH – hydrocodone/acetaminophen

[2] Drug Enforcement Administration – Hydrocodone

[3] NIH – Hydrocodone and Acetaminophen

[4] NIH – Hydrocodone Combination Products

[5] NIH – Hydrocodone