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Mixing Pepcid and Alcohol Safety, 8 Side Effects, Interactions & Alcohol Flush

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Pepcid and alcohol are an unwise combination for your liver. To begin, taking Pepcid and alcohol can trigger increased heartburn. Learn the effects, interactions & risks of mixing Pepcid-AC and alcohol.

Is Pepcid AC Safe With Alcohol?

Generally dangerous interactions between famotidine or Pepcid and alcohol have not been observed. But, side effects of drinking alcohol can aggravate heartburn, ulcers, and GERD symptoms. Additionally, alcohol can be trigger increased heartburn. Thus, Pepcid and alcohol should not be taken together.

Moreover, mixing Pepcid AC with Alcohol can worsen and negatively affect heartburn, ulcers, and GERD symptoms. Research indicates that H2 blockers, such as famotidine found in Pepcid, may actually increase blood alcohol level (BAL), also known as blood alcohol concentration (BAC) for those drinking and taking Pepcid AC at the same time. 

What is Pepcid used for?

Famotidine ( Pepcid) is used to treat stomach ulcers (gastric and duodenal), erosive esophagitis (heartburn or acid indigestion), and gastroesophageal reflux disease (GERD). GERD is a condition where the acid in the stomach washes back up into the esophagus. Pepcid and alcohol do not have an alcohol-drug interaction, and taking them is safe if you’ve been drinking. But it doesn’t mean there are no other side effects that may arise.

Stomach acid reflux characterizes the illness known as GERD in the esophagus. Pepcid is utilized to treat these problems where the stomach’s acidity is excessive (eg, Zollinger-Ellison syndrome, multiple endocrine neoplasias).

The class of drugs known as histamine H2-receptor antagonists or H2-blockers includes famotidine. It functions by reducing the amount of acid the stomach produces.

This medication is offered both with and without a prescription from your doctor. Each pill contains more medication in the prescribed form. See your doctor for the proper usage and dosage for your medical condition.

Is Pepcid AC Safe with Alcohol?

It’s always good to know more about the safety of how medications and alcohol may mix! Pepcid AC is approved by the United States Food and Drug Administration (FDA) to treat heartburn and other symptoms that result from an excess of acid in the stomach. It can do so through the active ingredient famotidine (its generic name), more broadly known as an H2 blocker, which blocks the histamine receptors responsible for triggering acid production. Given that famotidine targets acid in your stomach, it makes sense that you’d be concerned about your friends’ stomach linings. 

However, research indicates that famotidine is responsible for lowering acidity. While famotidine likely won’t hurt your friends’ stomach linings, it may not help them reduce redness due to drinking. While some people find that the medication helps reduce redness, no studies have shown that famotidine effectively treats redness resulting from drinking alcohol.

Can you take Pepcid with Alcohol?

Antacids can impact how well other prescriptions work, so do not take other medicines within 2 to 4 hours of taking an antacid. You can drink alcohol while taking antacids, but alcohol can irritate your stomach and worsen your symptoms.

Alcohol is a potential trigger for heartburn. Chronic alcohol use may further aggravate gastric ulcer disease. Other H2 blockers with less alcohol effect include famotidine (Pepcid, Zantac 360). Avoid drinking alcohol to help prevent heartburn.

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Taking Pepcid and Alcohol can have negative side effects where alcohol may cause more heartburn.  Pepcid is the brand name of a drug called Famotidine and is used to limit the amount of acid your stomach produces. This drug might be recommended by a doctor to those who suffer from heartburn or indigestion.
Taking Pepcid and Alcohol can have adverse side effects where alcohol may cause more heartburn. Pepcid is the brand name of a drug called Famotidine and is used to limit the amount of acid your stomach produces. A doctor might recommend this drug to those who suffer from heartburn or indigestion.
Famotidine (Pepcid AC) is used to treat stomach or intestinal ulcers. It works by reducing stomach acid. It can also help relieve heartburn from acid reflux and treat other conditions that cause excessive stomach acid secretion.
Famotidine (Pepcid AC) is used to treat stomach or intestinal ulcers. It works by reducing stomach acid. It can also help relieve heartburn from acid reflux and treat other conditions that cause excessive stomach acid secretion.
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Famotidine / Pepcid Drug Facts

Famotidine / Pepcid

Common brand names: Pepcid AC, Pepcid, Acid Controller

Antihistamine and Antacid

Purpose: to help treat ulcers, gastroesophageal reflux disease (GERD), and conditions that cause excess stomach acid. It can also treat heartburn caused by acid indigestion.


Brand Names: Pepcid AC, Pepcid, Acid Controller, Acid Reducer (famotidine), Heartburn Relief (famotidine), and Heartburn Prevention

Prescription sometimes needed

Pregnancy: No known risks

Alcohol: Avoid. Very serious interactions can occur

Drug class: H2 antagonist

To prevent heartburn, take 1 tablet by mouth with a glass of water 15-60 minutes before eating food or drinking beverages that cause heartburn.
To prevent heartburn, take 1 tablet by mouth with a glass of water 15-60 minutes before eating food or drinking beverages that cause heartburn.

Famotidine / Pepcid Side Effects

  1. Anxiety.
  2. blistering, peeling, or loosening of the skin.
  3. blood in the urine or stools.
  4. bloody, black, or tarry stools.
  5. difficulty breathing.
  6. discouragement.
  7. fast, irregular, pounding or racing heartbeat or pulse.
  8. feeling sad or empty.

Famotidine has no known severe interactions with any drugs.

Drug Class: Histamine H2 Antagonists, Gastro…

Brand Name: Pepcid


Check with your doctor right away if you have the following symptoms: confusion, delirium, hallucinations, disorientation, agitation, seizures, or unusual drowsiness, dullness, tiredness, weakness, or feeling of sluggishness. These are more likely to occur if you are older or if you have kidney disease.

Can you take Pepcid after Drinking Alcohol?

Immediately after drinking alcohol, some people notice a reddening (flushing) of the face, neck, or upper chest. It happens when a specific enzyme (protein) in the body is abnormal. Some people take antihistamines, like famotidine (Pepcid AC), to prevent this reaction.

However, alcohol can aggravate your stomach lining, causing abdominal pain and nausea. In contrast, medicines like the anti-nausea Zofran and antacids like Pepcid, Zantac, or Alka-Seltzer will help combat the shaky stomach of a post-party hangover sufferer.

Pepcid AC for Alcohol

Can you take Pepcid with alcohol? Patients suffering from acid reflux should avoid alcohol. However, Pepcid can be taken as an acid reducer for those suffering from acid reflux along with alcoholism under a healthcare professional’s care. You can take a Zantac or Pepcid-AC at least 45 mins before drinking or consuming foods that are likely to contribute to acid reflux. This can help social drinkers that have acid indigestion issues.

Pepcid AC for Alcohol Flush

Taking Pepcid to reduce acid heartburn may help avoid an “alcohol flush reaction.” However, long-term health hazards, such as an increased risk of stomach and esophageal cancer, may come with the abuse of Pepcid and related acid reflux medications. Alcohol flushing is generally described as:

  • An alcohol flush reaction induces redness in the face, nausea, and a faster heartbeat.
  • Alcohol-related flushing happens in people whose bodies don’t process alcohol normally. It’s most common in people of East Asian descent.
Pepcid and Alcohol. They're used as a treatment for alcoholism and basically give you near zero tolerance for alcohol.
Combining Pepcid and alcohol is not advised because alcohol can drive a higher potential for heartburn, countering Pepcid’s positive effect to reduce acid.

To prevent heartburn, take 1 Pepcid-AC tablet by mouth with a glass of water 15-60 minutes before eating food or drinking beverages that cause heartburn. Do not use more than 2 tablets in 24 hours unless directed by your doctor. You may be able to consume a limited amount safely as long as you follow specific rules (for example, waiting at least four hours after taking your daily dose before having an alcoholic drink).

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Can you Drink Alcohol with Pepcid?

Alcohol can irritate your stomach lining, causing abdominal pain and nausea. At the same time, medications like the anti-nausea Zofran and antacids like Pepcid, Zantac, or Alka-Seltzer will help combat the shaky stomach of a post-party hangover sufferer.

Pepcid-AC and Alcohol Drinking

Interactions between famotidine or Pepcid-AC and alcohol can counter the benefits of taking an acid reducer like Pepcid. Drinking alcohol can worsen heartburn, ulcers, and GERD symptoms; therefore, it is best avoided.

Pepcid And Alcohol Interactions

Famotidine has little impact on blood alcohol levels, so it is okay to drink alcohol in moderation while taking famotidine. However, alcohol can aggravate symptoms, and it is suggested that you avoid it altogether.

Although specific prescriptions should not be used concurrently, in other cases, two distinct medicines may be used together, even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary.

Pepcid And Alcohol Side Effects

Alcohol can worsen heartburn, ulcers, and GERD symptoms. Specific prescriptions should not be used at or around eating certain types of food since interactions may occur. Using alcohol or tobacco with specific prescriptions may also cause interactions to occur.

Common Pepcid Ac and Alcohol drug interactions by gender:

Female:

  • Eye movement disorder
  • Hepatic cirrhosis

Male:

  • Restless legs syndrome

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Pepcid Alcohol Side-Effects

Along with its needed effects, a prescription may cause some undesirable effects. Although not all of these side effects may occur, if they do occur, they may need medical attention. Consult with your doctor immediately if any of the following side effects occur:

Pepcid And Alcohol Rare Effects

  • Anxiety
  • Bleeding gums
  • Blistering, peeling, or loosening of the skin
  • Blood in the urine or stools
  • Bloody, black, or tarry stools
  • Cough
  • Difficulty breathing
  • Discouragement
  • Fast, irregular, pounding or racing heartbeat or pulse
  • Feeling sad or empty
  • Irritability
  • Lack of appetite
  • Loss of interest or pleasure
  • Noisy breathing
  • Pinpoint red spots on the skin
  • Seeing, hearing, or feeling things that are not there
  • Seizures
  • Swelling around the eyes
  • Tightness in the chest
  • Trouble concentrating
  • Trouble sleeping
  • Unusual bleeding or bruising

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Pepcid for Alcohol Intolerance

Although Pepcid is not intended to treat alcohol intolerance, it can reduce symptoms like alcohol flush reactions. By taking Pepcid before drinking, alcohol-intolerant people may be able to drink more before their symptoms force them to stop. Alcohol intolerance is a condition in which your body has trouble metabolizing alcohol. This permits toxins to accumulate and causes face flushing and other signs of alcohol intolerance.

Pepcid for Alcohol Redness

The alcohol flush response can cause redness of the face, nausea, and a faster heartbeat. Alcohol-related flushing occurs in people whose bodies don’t process alcohol naturally. It’s most typical in people of East Asian descent.

Pepcid and alcohol Asian Glow or Asian Flush. It’s usually what our friends, parents, and peers suggest when they suffer from this disorder, too. Pepcid, and Pepcid AC, are often suggested because these drugs can help ease getting a red face from alcohol.

Pepcid AC Alcohol Flush

Pepcid AC Alcohol Flush happens when a specific enzyme (protein) in the body is abnormal. Some people take antihistamines, like famotidine (Pepcid AC), to block this reaction.

The consumption of alcohol is widespread around the world, whether it is a beer at a football game or a drink during happy hour. According to estimates, roughly one-third of people worldwide consume alcohol. And while you may have heard that drinking a glass of wine every day is excellent for your heart, the evidence for this isn’t clear. But we have a lot of knowledge about how harmful alcohol is to the body. Long-term alcohol consumption can have adverse effects on practically every physiological system. The liver, heart, and brain are included in this.

Can you Drink Alcohol While Taking Pepcid?

Although famotidine in combination with alcohol hasn’t been proven hazardous or detrimental to the stomach lining, it may raise BAL. Generally, a rise in BAL may not be the reason for alarm when it occurs in moderation. However, taking famotidine while drinking excessively might result in more severe BAL increases.

Top 5 Popular Pepcid and Alcohol FAQs

  1. What is Famotidine? And What is it Used for?

    Famotidine is the active ingredient in PEPCID® and is a histamine-2 blocker. Famotidine works by decreasing the amount of acid the stomach produces.

  2. Can I take Pepcid to prevent heartburn?

    PEPCID AC provides heartburn relief that starts working in minutes and controls acid all day or all night,* but it can even prevent heartburn if taken 15 to 60 minutes before a meal.

  3. Can Pepcid be Crushed?

    Use PEPCID as directed on the product label. Do not crush tablets. Swallow the whole with a glass of water. Do not chew.

  4. Can you drink Alcohol while taking Famotidine?

    Avoid drinking alcohol to help prevent heartburn. Alcohol is a potential trigger for heartburn.

  5. Can you take Pepcid while Pregnant?

    If you are pregnant or breastfeeding, consult your doctor before using PEPCID.

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We Level Up NJ provides proper care with round-the-clock medical staff to assist your recovery through our medically-assisted detox program.

Pepcid and Alcoholism Treatment

For alcoholics using Pepcid and Alcohol, We Level Up NJ alcoholism and drug treatment center offers a comprehensive plan that includes evidence-based therapies, like cognitive behavioral therapy. CBT is essential for alcohol recovery. If you need help or a free assessment for alcohol use disorder reach out to one of our specialists for a free assessment. Depending on how badly your alcohol addiction has affected you, your treatment may be covered by insurance.

We Level Up NJ treatment center employs highly skilled addiction specialists who have undergone training to provide clients with the motivation and resources needed to stop abusing Pepcid and alcohol to sustain long-term health and sobriety. The We Level Up NJ rehabilitation center provides diagnostic treatment programs for people with these diseases and co-occurring mental health issues.

If you are facing Pepcid and Alcohol addiction, get in touch with us immediately to discuss your treatment options and find out how we can help you as you begin your recovery journey. We’ll be by your side the entire time.

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Sources

[1]  “Famotidine tablet.” DailyMed. Archived from the original on 14 July 2017. Retrieved 6 March 2021. [2] Escolano F, Castaño J, López R, Bisbe E, Alcón A (October 1992). “Effects of omeprazole, ranitidine, famotidine and placebo on gastric secretion in patients undergoing elective surgery.”
[3] Nehring SM, Freeman AM. Alcohol Use Disorder. [Updated 2022 Jul 31]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2022 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK436003/
[4] Newman RK, Stobart Gallagher MA, Gomez AE. Alcohol Withdrawal. [Updated 2022 Aug 29]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2022 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK441882/