By We Level Up NJ Treatment Center | Editor Yamilla Francese | Clinically Reviewed By Lauren Barry, LMFT, MCAP, QS, Director of Quality Assurance | Editorial Policy | Research Policy | Last Updated: February 28, 2023
Morphine Detox, Withdrawal Symptoms & Addiction Treatment
Approximately ten percent of all people in the United States have abused an opiate drug like morphine at least once. Morphine, as with other opioid drugs, may cause tolerance when an individual takes it regularly for a period of time, either through a prescription for pain relief or recreationally. In fact, morphine is often prescribed for a patient who has become tolerant to other opioid narcotics to manage pain.
Morphine detox is a process of getting off morphine that may require medical treatment, particularly if a person has a history of morphine addiction. Morphine is an addictive prescription drug that can be habit-forming. Injecting morphine for more than a few weeks can result in physical dependence and morphine withdrawal symptoms. Medically-assisted morphine detox may be necessary if a person has become physically dependent on the drug through chronic use of morphine or morphine abuse.
What is Morphine?
Morphine is a prescription opioid (narcotic) that is used to treat moderate to severe chronic pain. It is an opiate alkaloid secluded from the plant Papaver somniferum and produced synthetically. It is available in both short-acting and extended-release (XR) forms. This drug is a DEA-controlled drug and a DEA Schedule II controlled substance.
Substances in the DEA Schedule II have a high potential for abuse, leading to severe psychological or physical drug dependence. Therefore, the DEA classifies Morphine as a Narcotics (Opioids) drug. If you are addicted to Morphine, a comfortable Morphine detox program may provide the assistance and support you need to wean yourself off of the medication successfully.
In addition, street names for Morphine are Dreamer, Emsel, First Line, God’s Drug; Hows, MS, Mister Blue, Morpho, and Unkie. Morphine is recognized as the traditional opioid analgesic with which other painkillers are compared. Morphine alters how the brain and nervous system respond to pain. So, quitting morphine after a dependency has developed (without gradually tapering the dosage) is extremely difficult.
Morphine — aptly named for Morpheus, the Greek god of dreams — changes your body’s relationship to pain and, depending on the dose and your physiological response may cause euphoria. Morphine helps release the neurotransmitter dopamine, which blocks pain signals and creates a pleasurable feeling. This is why it works as a pain reliever.
What is Morphine Sulfate?
FDA-approved usage of morphine sulfate includes moderate to severe pain that may be acute or chronic. Most commonly used in pain management, morphine provides significant relief to patients afflicted with pain. Morphine is widely used off-label for almost any condition that causes pain. In the emergency department, morphine is given for musculoskeletal pain, abdominal pain, chest pain, arthritis, and even headaches when patients fail to respond to first and second-line agents.
How Morphine is Administered?
Morphine administration can occur through various vehicles. Its administration is most often via the following routes: orally (PO), intravenously (IV), epidural, and intrathecal. Oral formulations are available in both immediate and extended-release for the treatment of acute and chronic pain.
Infusion dosing can vary significantly between patients and largely depends on how naive or tolerant they are to opiates. It is interesting to point out that IV morphine formulation is also commonly given intramuscularly (IM). Morphine is also available as a suppository.
Morphine is widely used and abused. As a result of this, people have found ways to insufflate (snort) the medication. Morphine is also available as an oral solution and can be administered sublingually. Sublingual morphine is very popular in palliative care.
What is 54 733 Pill?
The pill with imprint 54 733 is white (white pill 54 733), round, and has been identified as Morphine Sulfate 15 mg. 54733 pills, or 54733 white round is supplied by Hikma Pharmaceuticals PLC.
What is 54 262 Pill?
The pill with imprint 54262 pill is white, and round and has been identified as Morphine Sulfate 30 mg. 54262 pills are supplied by Hikma Pharmaceuticals PLC.
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Morphine Addiction Statistics
Opioid abuse has been increasing over the past ten years. Opioid abuse is rarely seen before the late teens or early 20s. However, it can develop at any age. Among adults over 18, prevalence rates have been estimated at .37%. The male-to-female ratio for opiates other than heroin is 1.5 to 1. The highest prevalence rates are found in individuals aged 29 or younger (.82%), after which the disorder decreases until it reaches an estimated rate of .09% in those ages 65 or older.
10% of the US population has abused an Opiate drug in their lifetime.
The number of Morphine addicts admitted to the emergency room increased by 106% between the years 2004 and 2008.
More than 60% of Morphine addicts admitted to getting the drug from friends or relatives.
Morphine Drug Fact
Morphine sulfate is an opioid agonist indicated for the relief of moderate to severe acute and chronic pain where the use of an opioid
analgesic is appropriate
Why is this medication prescribed?
Morphine is used to relieve moderate to severe pain. Morphine extended-release tablets and capsules are only used to relieve severe (around-the-clock) pain that cannot be controlled by the use of other pain medications.
Morphine extended-release tablets and capsules should not be used to treat pain that can be controlled by medication that is taken as needed. Morphine is in a class of medications called opiate (narcotic) analgesics. It works by changing the way the brain and nervous system respond to pain.
How should this medicine be used?
Morphine comes as a solution (liquid), an extended-release (long-acting) tablet, and as an extended-release (long-acting) capsule to take by mouth. The oral solution is usually taken every 4 hours as needed for pain. MS Contin brand and Arymo ER brand are extended-release tablets that are usually taken every 8 or every 12 hours.
Morphabond brand extended-release tablets are usually taken every 12 hours. Kadian brand extended-release capsules are usually taken with or without food every 12 hours or every 24 hours. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand.
Morphine can potentially be a lethal medication when not used properly. It causes a host of symptoms related to depression in the CNS. Severe respiratory depression is the most feared complication of morphine in cases of overdose. Immediate injection of naloxone is required to reverse the effects of morphine.
Adverse Effects & Toxicity of Morphine
Morphine can potentially be a lethal medication when not used correctly because it causes a host of symptoms related to depression in the CNS. Severe respiratory depression is the most worrying complication of Morphine in cases of overdose. Therefore, an urgent injection of naloxone is needed to reverse the effects of Morphine.
If symptoms of an overdose happen, a friend or family member should give the first dose of naloxone, call 911 immediately, stay with you and watch you closely until emergency medical help arrives. Your symptoms may return within a few minutes after you receive naloxone. If your symptoms return, the person should give you another dose of naloxone. Additional amounts may be given every 2 to 3 minutes if symptoms return before medical help arrives.
Symptoms of Morphine Overdose
- Slow, Shallow, or Irregular Breathing
- Unable To Respond or Wake Up
- Limp Muscles
- Cold, Clammy Skin
- Small Pupils
- Slow Heartbeat
- Blurred Vision
Morphine Detox Withdrawal Symptoms
Withdrawal occurs when a person who has become dependent on Morphine quits using the drug. Morphine is an opioid, like heroin, and some prescription painkillers such as oxycodone. Withdrawal begins when opioid receptors in the brain no longer have access to Morphine. Consequently, this triggers several symptoms that can persist for several days. In isolated cases, severe symptoms of opioid withdrawal can become life-threatening.
Although morphine withdrawal symptoms may seem unpleasant and scary, discontinuing Morphine and other opioids is the best option for your long-term health.
Morphine detox withdrawal symptoms may include the following:
- Flu-like symptoms, such as fever, chills, or body aches
- Diarrhea and Vomiting
- Dilated Pupils
- Depression or Anxiety
- A strong desire to use Morphine
People who inject Morphine intravenously are more unsafe and prone to hepatitis, HIV, and life-threatening infections. These can exacerbate withdrawal and increase the risk of severe symptoms.
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Signs and Symptoms Associated with the Morphine Abuse
The Most Common Side Effects Associated with the Use of Morphine include:
- Weight Loss
- Loss of Appetite
- Mood Swings
- Body Aches
- Stiff Muscles
More acute side effects include abnormal heartbeat, breathing difficulty, vision problems, seizures, and hallucinations. Over time, users can develop a dependency on the drug. It also has the potential for the brain to be permanently altered significantly when you abused the drug.
Morphine Medical Detox, How To Relieve Opioid Withdrawal Symptoms
There are various morphine withdrawal symptoms when a person chooses to discontinue using morphine. These include:
- Watery Eyes
- Runny Nose
- Emotional Trauma
- Psychological Trauma
- High blood pressure can lead to heart attack and stroke
These symptoms can often last several days. For that reason, it is usually prescribed for users to undergo IV therapy medical detox rather than self-reporting outpatient detox. In fact, this is more trustworthy and more effective for chronic users of Morphine.
In addition, it makes the clients more comfortable because there is continuous supervision and adjustment of IV medications that help keep withdrawal symptoms under control.
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The acute (immediate) symptoms of opioid withdrawal rarely last longer than one week, but that doesn’t imply you’re out of the woods entirely. A longer-lasting withdrawal syndrome, known as protracted withdrawal, affects some people for as long as six months after their last dose.
Protracted withdrawal is much less severe than acute withdrawal, and it tends to be more psychological than physical.
This severe case is manageable at a treatment center where you can have access to medical or treatment experts that are always ready to support you.
Symptoms of Prolonged Opioid Withdrawal include:
- Low energy levels
- Low tolerance for stress (short fuse)
- Trouble sleeping
- The inability to experience pleasure from anything
- Problems with memory or concentration
- Irritability or agitation
For some people, recovery from opioid dependence is a long-term, ongoing process. The best long-term treatment for you will depend on a few key determinants, namely the presence of addiction and its severity.
Some of the Signs of Opioid Addiction
Chronic use of Morphine can damage one’s mental and physical abilities while also lessening their level of consciousness. Women who use Morphine while pregnant put their unborn babies at serious risk of dependency and withdrawal symptoms.
Indications of Morphine Addiction
- Continuing to use drugs notwithstanding the negative results of your drug use
- Spending excessive numbers of time using drugs or recovering from their effects
- Spending excessive amounts of time thinking about your next dose or how to get it
- Failing to meet your obligations at home, work, or school
- Experiencing intense cravings that intervene with your life
- Trying to quit but being powerless to do so
The evidence overwhelmingly proves that once a moderate to severe opioid use disorder has developed, tapering without the support of medications is ineffective. Therefore, evidence-based treatment for opioid use disorder includes a combination of medication and behavioral therapy.
This means managing drugs like methadone or Suboxone in combination with talk therapy. Given that, research has found that combining therapy and medication works better than medication alone. Just be cautious of withdrawal symptoms.
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How Morphine Detox Works?
Detoxing from morphine is a multi-step process. Within a detox center, there are three primary steps in this fast morphine detox and withdrawal process.
Steps in the accelerated morphine detox process include:
- intake assessment: You’ll first be assessed physically and psychologically. You may be asked questions about your medication history and substance use.
- detoxification: Morphine withdrawal can begin within 24 hours of your last morphine use. This can last anywhere from four days to two weeks.
- drug rehab: After detox, a transition into a drug rehab program for morphine abuse may be recommended to help you maintain abstinence from morphine.
Morphine detox services are offered by detox facilities, outpatient detox centers, and some inpatient addiction treatment centers.
How Long To Detox From Morphine?
Morphine detox in general lasts five to seven days. Withdrawal duration and severity can be influenced by many contributing factors, such as:
- Duration and amount of morphine use: The longer and more morphine someone uses on a regular basis, the more likely the person is to be more heavily dependent on the drug.
- Biological or genetic influences: Personal or family history of addiction and other biological factors can contribute to a person’s level of drug dependence.
- Co-occurring disorders: Underlying medical or mental health conditions may impact drug dependence, treatment, and withdrawal.
- Polydrug abuse: Abusing more than one drug, or alcohol, with morphine, can increase the odds of developing a more significant dependence more rapidly and will need to be addressed during detox.
- Environmental factors: Stress, peer pressure, and a person’s external environment can also contribute to drug abuse and dependence.
Morphine detox is an individual experience. As a result, morphine withdrawal symptoms and the morphine detox timeline may vary somewhat from person to person.
Morphine Withdrawal Timeline
Morphine withdrawal symptoms happen right after your last dose has worn off. Symptoms can last from several days to a few weeks. Generally, morphine withdrawal is like bad flu. The worst symptoms show two to four after quitting the morphine. After the first week, the symptoms slowly become less and less intense.
Below is a detailed morphine withdrawal symptoms timeline to easily assist a person in predicting a general timeline of symptoms during this difficult period:
0-48 hours after the last morphine dose:
- Abdominal cramps
- Loss of appetite
- Muscle & body aches
- Panic attacks
3-5 days after the last morphine dose:
- Heart palpitations
- Mild nausea
- Sleep disorders
5-7 days after the last morphine dose:
- Cravings Stabilization
- Mood swings
- Sleep disorders
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Morphine Addiction Treatment Near Me
Morphine addiction is a chronic disease and should be treated like other chronic diseases. Like those, it should constantly be monitored and managed. Morphine is a type of opioid. Opioid addiction treatment is different for each individual. The main purpose of opioid addiction treatment is to help the person stop using the drug. Opioid addiction treatment can also help the person avoid using it again.
The body goes through specific symptom stages known as opiate withdrawal. The opiate withdrawal timeline varies from a few days to a few weeks, depending on the type of opioid used, how long it was used, and any other substances that may have been used in conjunction with opioids. Medically managed withdrawal opiate detox ensures the individual remains safe and stays as comfortable as possible.
Morphine Detox Treatment
The first step in treatment is medical detox. It will help you navigate the complicated withdrawal process but doesn’t address patterns of thought and behavior contributing to Morphine addiction. Various treatment approaches and settings can help provide the ongoing support necessary to maintain long-term sobriety after you complete detox.
Cravings are very common during detox and can be challenging to overcome. This often leads to relapse. Constant medical care provided during inpatient treatment helps prevent relapse. Clinicians can give the necessary medication and medical expertise to lessen cravings and the effects of withdrawals.
Inpatient Morphine Withdrawal Treatment
There isn’t one treatment approach or style that will suit everyone. Treatment should speak to the needs of the individual. Inpatient drug rehab and addiction treatment aren’t just about drug or alcohol use. the goal is to help the person stop using drugs like Morphine. Drug and alcohol rehab should also focus on the whole person’s needs.
Addiction is a complex but treatable disease that affects brain function and behavior. When someone or their family is considering different treatment facilities, they should account for the complexity of addiction and the needs of the individual. The objective of attending an inpatient drug and alcohol rehab center for addiction treatment is to stop using the drug and re-learn how to live a productive life without it.
Most people benefit from inpatient rehab after a full medical detox from drugs and alcohol. Inpatient drug rehab can last anywhere from 28 days to several months. Patients stay overnight in the rehab facility and participate in intensive treatment programs and therapy. Once someone completes rehab, their addiction treatment team will create an aftercare program, including continuing therapy and participation in a 12-step program like Alcoholics Anonymous and Narcotics Anonymous.
Many rehab programs will also have early morning classes or programs. Group sessions occur during inpatient rehab, as do individual therapy sessions. Family therapy may be part of inpatient rehab when it’s feasible. Alternative forms of therapy may be introduced during inpatient rehab, like a holistic therapy program, yoga for addiction recovery, or addiction treatment massage therapy.
Several different modalities of psychotherapy have been used in the treatment of mental health disorders along with addiction, including:
- Cognitive Behavioral Therapy (CBT) – is an effective treatment that involves changing both the patterns of negative thoughts and the behavioral routines which are affecting the daily life of the depressed person for various forms of depression.
- Dialectical Behavioral Therapy (DBT) – is a comprehensive mental health and substance abuse treatment program whose ultimate goal is to aid patients in their efforts to build a life worth living. The main goal of DBT is to help a person develop what is referred to as a “clear mind.”
- Solution-focused therapy is an approach interested in solutions that can be quickly implemented with a simple first step leading to further positive consequences.
Dual Diagnosis Treatment
Drug abuse and mental health disorders often co-occur. In many cases, traumatic experiences can result in mental health disorders and substance abuse. Dual-diagnosis rehabilitation treats both of these issues together. The best approach for the treatment of dual diagnosis is an integrated system. This strategy treats both the substance abuse problem and the mental disorder simultaneously. Regardless of which diagnosis (mental health or substance abuse problem) came first, long-term recovery will depend mainly on the treatment for both diseases done by the same team or provider.
Medication Assisted Treatments (MAT)
Medication-Assisted Treatments (MAT) for substance use and mental health disorders are commonly used in conjunction with one another. This includes the use of medications and other medical procedures. During your rehab, the staff from your treatment facility will help you identify what caused your addiction and teach you skills that will help you change your behavior patterns and challenge the negative thoughts that led to your addiction. Sometimes, the pressures and problems in your life lead you to rely on substances to help you forget about them momentarily.
Please, do not try to detox on your own. The detox process can be painful and difficult without medical assistance. However, getting through the detox process is crucial for continued treatment. We Level Up provide proper care with round-the-clock medical staff to assist your recovery through our opioid addiction treatment program medically. So, reclaim your life, and call us to speak with one of our treatment specialists. Our counselors know what you are going through and will answer any of your questions.
Search We Level Up NJ “Morphine Detox, Withdrawal Symptoms & Addiction Treatment” Topics & Resources
 Morphine: MedlinePlus Drug Information
 Morphine Addiction – We Level Up Treatment Centers
 Morphine Sulfate tablets label (fda.gov)
 Human Abuse Potential of an Abuse-Deterrent (AD), Extended-Release (ER) Morphine Product Candidate (Morphine-ADER Injection-Molded Tablets) vs Extended-Release Morphine Administered Intranasally in Nondependent Recreational Opioid Users – PMC (nih.gov)
 Morphine And Alcohol, 1st Class Polydrug Abuse Rehab Center (welevelup.com)
 Morphine – StatPearls – NCBI Bookshelf (nih.gov)
 The Mechanisms Involved in Morphine Addiction and Morphine Antidote – PMC (nih.gov)
 Effect of Physical Activity on Symptoms of Morphine Addiction in Rats, after and before of Lesion of the mPFC Area – PMC (nih.gov)
 Treatment Approaches for Drug Addiction DrugFacts | National Institute on Drug Abuse (NIDA) (nih.gov)
 EARLY INTERVENTION, TREATMENT, AND MANAGEMENT OF SUBSTANCE USE DISORDERS – Facing Addiction in America – NCBI Bookshelf (nih.gov)