How Long Does Xanax Stay in System? Signs of Xanax Addiction

How Long Does Xanax Stay in System?

Xanax, the brand name for Alprazolam, is likely the most popular drug in the benzodiazepine class. Xanax calms the nerves and produces a feeling of relaxation at standard doses, which come in pill form. If taken at high doses, especially if crushed and snorted or mixed into a solution for injection, it can create a euphoric high.

On average, Xanax has an elimination half-life of about 11 hours (though the range is from about 6-27 hours—sometimes higher in obese patients). This means that it takes a healthy person’s body this amount of time to get rid of half of a dose of the drug.

Because the body breaks down alprazolam quickly, lab tests don’t usually detect the drug itself. Instead, they typically look for α-hydroxyalprazolam, its metabolite. Virtually all drug tests screen for alpha hydroxyalprazolam. This includes the most basic 10-panel tests.

That said, there are several types of lab tests. Each one can yield different results and will detect the metabolite during a distinct window. The four most common, which will be detailed below, include:

Xanax Addiction Statistics

Benzodiazepines, such as Xanax are often used for the short-term treatment of anxiety. While benzodiazepine use is highly prevalent among U.S. adults, public health experts have not known what proportion of benzodiazepine users misuse them or meet criteria for benzodiazepine use disorders. A recent analysis suggests that benzodiazepine use disorders are relatively rare among the adults who use benzodiazepine medications, even if they are misusing them.

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What is Xanax and What is it Used for?

Xanax is the brand name of alprazolam, a benzodiazepine prescription drug. Benzodiazepines are central nervous system (CNS) depressants, which are used to treat anxiety, insomnia, muscle rigidity, and seizures. Xanax is specifically used to treat Generalized Anxiety Disorder (GAD) and panic disorder.

GAD can be diagnosed when you experience three or more of the following symptoms more often than not for six months or more:

• Continuous, extreme, and unrealistic worry about everyday things
• Anticipating disastrous consequences
• Excessive worry about money, health, family, work, etc.
• Restlessness or edginess
• Uneasiness
• Becoming tired easily
• Having difficulty concentrating
• Irritability
• Tense muscles
• Troubled sleep, including having trouble falling asleep or staying asleep, or experiencing restless sleep

Factors That Influence How Long the Effects of Xanax Last

A number of factors can influence the time it takes for Xanax to clear the body. These include:

Age

The half-life of Xanax is higher in elderly people. Studies have found that the average half-life is 16.3 hours in healthy elderly people, compared to an average half-life of roughly 11 hours in younger, healthy adults.

Weight

For obese individuals, it may be more difficult for your body to break down Xanax. The half-life of Xanax in people who are obese is higher than average. It ranged between 9.9 and 40.4 hours, with an average of 21.8 hours.

Ethnicity

Studies have found that the half-life of Xanax is increased by 25 percent in Asians compared to Caucasians.

Metabolism

A higher basal metabolic rate may decrease the time it takes for Xanax to leave the body. People who exercise regularly or have faster metabolisms may be able to excrete Xanax faster than people who are sedentary.

Liver Function

It takes longer for people with alcoholic liver disease to break down, or metabolize, Xanax. On average, the half-life of Xanax in people with this liver problem is 19.7 hours.

Dosage

Each tablet of Xanax contains 0.25, 0.5, 1, or 2 milligrams (mg) of alprazolam. In general, higher doses will take longer for your body to fully metabolize.

The total length of time you’ve been taking Xanax will also affect how long the effects last in your body. People who have been taking Xanax on a regular basis will consistently maintain a higher concentration in their bloodstream. It will take longer to fully eliminate all of the Xanax from your body, though you may not necessarily “feel” the sedative effects for longer because you’ve built up a tolerance to the medication.

Other Medications

Xanax is cleared by your body through a pathway known as cytochrome P450 3A (CYP3A). Drugs that inhibit CYP3A4 make it more difficult for your body to break down Xanax. This means that the effects of Xanax will last longer.

Medications that increase the time it takes for Xanax to leave the body include:

• azole antifungal agents, including ketoconazole
  and itraconazole
• nefazodone (Serzone), an antidepressant
• fluvoxamine,a drug used to treat obsessive-compulsive
  disorder (OCD)
• macrolide antibiotics such as erythromycin and clarithromycin
• cimetidine (Tagamet), for heartburn
• propoxyphene, an opioid pain medication
• oral contraceptives (birth control
  pills)

On the other hand, certain medications help to induce, or speed up the process, of CYP3A. These medications will make your body break down Xanax even faster. An example is the seizure medication carbamazepine (Tegretol) and an herbal remedy known as St. John’s wort.

Alcohol Use

Alcohol and Xanax taken in combination have a synergistic effect on one another. This means that the effects of Xanax are increased if you consume alcohol. It will take longer to clear Xanax from your body. Combining alcohol with Xanax can lead to dangerous side effects, including the possibility of a fatal overdose.

Why Do People Abuse Xanax?

People may abuse Xanax for a variety of reasons. Some people take Xanax to get high or for recreational purposes, taking several pills at a time. In fact, Xanax is popular amongst high school students and young adults, according to several studies conducted by drug abuse experts. 

People who abuse Xanax can get addicted within two weeks. They usually either crush Xanax into a powder and snort it or mix it with water and inject it. Others might abuse the drug because they are addicted to it, believing that they need to take more of the drug in order to feel how they initially felt when taking it.

People can also become psychologically dependent on benzodiazepines like Xanax. Because benzodiazepines are so effective at treating anxiety, many who suffer from severe anxiety issues may feel that they cannot cope without their medication. When someone becomes psychologically dependent on Xanax, quitting cold turkey can produce uncomfortable withdrawal symptoms.

An interesting piece of information about how long Xanax stays in your urine is that benzodiazepines are one of the most commonly abused classes of drugs. Benzodiazepines were also found to be one of the more common drugs used recreationally at dance clubs or parties and other places where people combine them with other substances.

Taking Xanax or other benzodiazepines can introduce tolerance, or even withdrawal symptoms into the picture. Since Xanax is often taken with other substances, it can also cause dangerous interactions with drugs like alcohol. For example, since Xanax and alcohol are both depressants, when used together they can slow a person’s breathing and cause that person to experience a fatal overdoes. 

Since benzodiazepines are so addictive, does this mean you will fail a drug test for them if you stop taking them? Yes and no. If you’ve been using benzodiazepines for an extended period of time or in very high doses, it’s possible to have a detectable amount of the medication in your system up to a month after stopping use. Some studies involving individuals who are going through detox and have been on high-dose benzos report more extreme numbers, such as 90 days or longer before tests return to normal results.

Xanax Addiction Treatment 

There is a strong link between mental health and substance abuse. Individuals who struggle with mood disorders like depression and anxiety are more susceptible to developing an addiction to drugs or alcohol, often to self-medicate symptoms of their underlying mental health condition. These co-occurring disorders can make each other worse without proper treatment.

To determine the most effective ways of Xanax addiction treatment, it’s crucial to get an accurate assessment of all the symptoms. When a mental health professional has evaluated the symptoms, it may be determined that another form of mental condition is present and needs a particular treatment. Very often, some combination of psychotherapy, medication, and lifestyle changes effectively cope with functional.

Medically Assisted Detox

Medical detox is often considered the first stage of treatment. It will help you navigate the complicated withdrawal process but doesn’t address patterns of thought and behavior contributing to drug abuse. Various treatment approaches and settings can help provide the ongoing support necessary to maintain long-term sobriety after you complete detox.

Cravings are very common during detox and can be challenging to overcome. This often leads to relapse. Constant medical care provided during inpatient treatment helps prevent relapse. Clinicians can offer the necessary medication and medical expertise to lessen cravings and the effects of withdrawals.

Psychotherapy for Depression and Anxiety

Several different modalities of psychotherapy have been used in the treatment of depression, including:

• Cognitive Behavioral Therapy (CBT) – An effective treatment that involves changing both the patterns of negative thoughts and the behavioral routines which are affecting the daily life of the depressed person for various forms of depression.
• Person-Centered Therapy – A strategy that allows and encourages clients to understand and resolve their concerns in a safe, supportive environment.
• Solution-Focused Therapy – Approach interested in solutions that can be quickly implemented with a simple first step leading to further positive consequences.

Xanax Dual Diagnosis Treatment

Substance abuse and mental health disorders often co-occur. In many cases, traumatic experiences can result in mental health disorders and substance abuse. Dual-diagnosis rehabilitation treats both of these issues together. The best approach for the treatment of dual diagnosis is an integrated system. This strategy treats both the substance abuse problem and the mental disorder simultaneously. Regardless of which diagnosis (mental health or substance abuse problem) came first, long-term recovery will depend largely on the treatment for both disorders done by the same team or provider.