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How Long Does Vyvanse Last in the System?

Vyvanse is a pro-drug, which means that for it to work over time, it must be taken orally and digested by the body. As a result, Vyvanse may take one to two hours to start working, and its effects may continue for up to 14 hours.

Vyvanse is a prescription drug that activates the nervous system. It is often advised to treat the signs and symptoms of attention deficit hyperactivity disorder (ADHD) in adults and children aged six and older. Like other ADHD drugs, Vyvanse improves concentration, impulse control, ability to concentrate, and other symptoms by increasing neurotransmitters dopamine and norepinephrine levels in the brain to balance out chemical imbalances. Vyvanse is the only drug of its kind that has been approved to treat binge eating disorders.

What is Vyvanse?

Vyvanse is a stimulant drug available only by prescription and frequently used to treat ADHD in adults and children. The medication is also used to treat moderate-to-severe binge eating disorders.

The greatest concentration of Vyvanse and its breakdown products are present in the bloodstream after 3.5 hours. Lisdexamfetamine, the active ingredient, completely exits the plasma after a few hours. However, lisdexamfetamine, sold under the brand name Vyvanse, breaks down into other substances that may linger in a person’s body for much longer.

Given that it stimulates the central nervous system, Vyvanse is equivalent to stimulants like Adderall and Ritalin. Vyvanse and other stimulants improve focus and concentration in ADHD patients while raising blood pressure and other nervous system processes like heart rate.

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Vyvanse Fact Sheet

Vyvanse (Lisdexamfetamine)

Lisdexamfetamine is a medication prescribed to adults and children six years of age and older to treat the symptoms of attention deficit hyperactivity disorder (ADHD; more trouble focusing, managing behaviors, and remaining still or quiet than other individuals their age).

Adults with binge eating disorders can also benefit from lisdexamfetamine treatment (an eating disorder characterized by periods of uncontrolled overeating). The medication lisdexamfetamine belongs to the drugs known as central nervous system stimulants. It functions by altering the concentrations of specific organic compounds in the brain.

Vyvanse Information

COMMON BRANDS

Vyvanse®

CONTROLLED SUBSTANCE CLASSIFICATION

Vyvanse is classified as a Schedule II controlled substance. Schedule II drugs, substances, or chemicals are defined as drugs with a high potential for abuse.

AVAILABILITY

This medication needs prescription authorization from your doctor only.

Vyvanse Abuse Statistics

According to a Drug Abuse Warning Network report from 2012, Vyvanse’s non-medical use resulted in 2,014 emergency room visits and 116 people enrolling in addiction programs.

Studies that surveyed persons in the U.S. suggested that 7% to 8% had used prescription stimulants like Vyvanse for nonmedical purposes throughout their lifetime. In addition, up to 17% of college students are thought to misuse prescription stimulants. Most patients who take stimulants recreationally are between 18 and 25. More than half (56.3%) of the stimulant users cited that cognitive enhancement is the main reason for misusing prescription stimulants, such as Vyvanse.


7-8%

Studies that surveyed persons in the U.S. suggested that 7% to 8% had used prescription stimulants like Vyvanse for nonmedical purposes throughout their lifetime. In addition, up to 17% of college students are thought to misuse prescription stimulants. Most patients who take stimulants recreationally are between 18 and 25.

Source: NIDA

56%

More than half (56.3%) of the stimulant users cited that cognitive enhancement is the main reason for misusing prescription stimulants, such as Vyvanse.

Source: NIDA


Vyvanse Half Life & Effects

The half-life of a drug is frequently used to estimate or measure how long it stays in a person’s system. In other words, it is time it takes normal metabolic processes to reduce the concentration of the drug by half. The stimulant dextroamphetamine is produced naturally when the active ingredient in the half life of Vyvanse, lisdexamfetamine, is metabolized. How long does Vyvanse last? Detection of lisdexamfetamine would only last a brief time (only a few hours in most cases). Dextroamphetamine would be more readily detected because of its extended half-life of roughly 12 hours.

How long does Vyvanse last? It can be assumed that a particular drug’s elimination from the body takes around 5.5 half-lives. The person’s weight, gender, whether or not the drug was taken in conjunction with other medications, and how much of the drug was taken are just a few of the many variables that might impact how quickly any drug is metabolized. How long does it take Vyvanse to work? According to some studies, Vyvanse improves attention in people with ADHD for 2 hours and up to 14 hours after dosage. It is a long-acting drug that releases throughout the day.

A variety of circumstances may have an impact on whether a drug is detectable in the body. For instance, the detectability window should be calculated from the person’s most recent drug use rather than when they first started taking it if they were to take multiple doses of Vyvanse separated several hours apart.

How long does Vyvanse work? The effects of Vyvanse can last for up to 14 hours.
How long does Vyvanse work? The effects of Vyvanse can last for up to 14 hours.
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How Long Does it Take For Vyvanse to Kick In?

How long does Vyvanse take to work? And how long does Vyvanse last? Clinical studies have demonstrated that Vyvanse improves attention in individuals with ADHD at 2 hours and up to 14 hours following a dosage. It is a long-acting medication that releases gradually throughout the day.

How Long Does 30mg Vyvanse Last?

Vyvanse comes in a range of dosages from 10 mg to 70mg. However, 30mg is the suggested starting dose. To assist control symptoms of ADHD and manage side effects, your doctor may occasionally increase or reduce your dosage. How long does Vyvanse last? Vyvanse has a maximum daily dose of 70 mg, and its effects can last up to 14 hours on average.

How Long Does 40mg Vyvanse Last?

How long does Vyvanse last? The usual dose of Vyvanse can be anywhere from 10-70mg. At 40mg, it has the same effects wherein Vyvanse can last for 10-14 hours on average.

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How long does Vyvanse take to kick in? Some studies show that Vyvanse begins to work after about 2 hours, increasing attention in ADHD patients for up to 14 hours following administration. A long-acting medication, it releases gradually throughout the day.
How long does Vyvanse take to kick in? Some studies show that Vyvanse begins to work after about 2 hours, increasing attention in ADHD patients for up to 14 hours following administration. A long-acting medication, it releases gradually throughout the day.

Vyvanse Side Effects

How long does Vyvanse last? Depending on individual characteristics, some people may eliminate Vyvanse more quickly than others. For instance, a higher dose of Vyvanse than a lower dose may result in quicker drug clearance. People who are ill or have organ failure may gradually stop taking medications. The same applies to older people who take other medicines that could interfere with Vyvanse.

According to studies on ADHD, Vyvanse side effects may include the following:

  • Loss of appetite or reduced appetite (anorexia)
  • Anxiety
  • Reduced weight
  • Diarrhea
  • Dizziness
  • Mouth ache
  • Irritability
  • Insomnia
  • Nausea
  • Upper abdominal pain
  • Vomiting

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How Long Does Vyvanse Last in the System?

Compared to other prescribed drugs like methylphenidate, Vyvanse was first thought to have a lower risk of abuse. Vyvanse, however, is a potential drug of abuse since drug users frequently have a strong desire to try various drugs and personalize them to their needs.

Vyvanse how long does it last? Several factors can affect whether a medication is detectable in a person’s system. The shortest detection window is frequently found in blood testing. The average person’s blood would typically continue to show Vyvanse in it for up to 8 hours after taking it. For up to three days and maybe a little longer, urine tests should be able to identify Vyvanse or its metabolites.

How long does Vyvanse stay in your urine? Vyvanse itself does not appear in the urine. Vyvanse instead changes into amphetamine, which can be found in urination. Urine samples are tested for the presence of dextroamphetamine or lisdexamfetamine. How long does Vyvanse last? Urine testing may detect Vyvanse residues 3–5 days after the last dose.

Hair analysis often has the most extended detection window. However, it can take a few days before a hair sample tests positive for Vyvanse or its metabolites. Usually, Vyvanse was detectable in a hair sample a month or so after a person used it.

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Vyvanse Addiction Treatment

Drug addicts dependent on Vyvanse can benefit from a comprehensive We Level Up NJ treatment plan that includes evidence-based and cognitive behavioral therapy. Depending on how severely their drug addiction has affected them, certain people with drug use disorders may be suitable for treatment at a dedicated facility like ours.

We work with highly qualified addiction specialists to provide patients with the knowledge and solutions they need to stop drug addiction and maintain their long-term health. We provide dual-diagnosis treatment programs for those who suffer from both these and co-occurring mental health conditions.

If you are battling drug addiction, contact us to discuss your treatment options and learn how we can support you as you start your recovery. We will be there for you at every moment. We Level Up NJ offers proper care with a 24-hour medical staff to support your recovery through our medication-assisted treatment program. Call us immediately to speak with a therapy expert and reclaim your life. Because they are aware of your struggles, our therapists will handle your concerns.

Experiencing drug dependency? Recover quickly at We Level Up NJ treatment centers!
Experiencing drug dependency? Recover quickly at We Level Up NJ treatment centers!

Popular Vyvanse FAQs

How long for Vyvanse to kick in? And how long does it take for Vyvanse to work?

According to some studies, Vyvanse improves attention in people with ADHD for 2 hours and up to 14 hours after dosage. It is a long-acting drug that releases throughout the day.

How long does Vyvanse last? and how long does Vyvanse show up in urine?

The actual drug Vyvanse does not show up in the urine. Instead, Vyvanse turns into amphetamine, which is excreted in the urine. Dextroamphetamine and lisdexamfetamine are both tested for in urine samples. Three to five days following the last dose, Vyvanse remains may be seen in the urine.

How long does it take to lose weight on Vyvanse?

Vyvanse doesn’t help with weight loss. Long-term amphetamine use can lead to a person eating more, preventing weight loss.

How long do Vyvanse stay in your system? And how long does Vyvanse last?

Usually, Vyvanse stays in your system for 64 hours, but with drug tests, detection can last as long as 90 days.

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Sources
  1. (2008) Substance Use Disorders in Children and Adolescents With Attention-Deficit/Hyperactivity Disorder: Implications for Treatment and the Role of the Primary Care Physician. The Primary Care Companion to the Journal of Clinical Psychiatry. from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2446489/  
  2. (September 2013) Assessing prescription stimulant use, misuse, and diversion among youth 10 to 18. Current Opinion in Psychiatry. from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5832028/  
  3. Vyvanse (lisdexamfetamine dimesylate). U.S. Food and Drug Administration. from https://www.accessdata.fda.gov/drugsatfda_docs/label/2007/021977lbl.pdf
  4. (September 2016) Prescription Drug Use and Misuse in the United States: Results from the 2015 National Survey on Drug Use and Health. Substance Abuse and Mental Health Services Administration. from https://www.samhsa.gov/data/sites/default/files/NSDUH-FFR2-2015/NSDUH-FFR2-2015.htm  
  5. (May 2011) Bulimia Nervosa Among Methamphetamine Dependent Adults: Association With Outcomes 3 Years After Treatment. Eating Disorders. from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3159413/.