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What is MDMA (Molly)?

Many people have heard of the drug ecstasy. It’s synthetic and, at least in the lab, it’s known as MDMA, short for 3,4-methylenedioxymethamphetamine [1]. Ecstasy gained popularity at nightclubs in 1980s and ’90s. The pills gave users the euphoric high of amphetamines and the psychedelic effects of hallucinogens. Molly contains all MDMA in a crystalline powder contained in a capsule. So, it’s a concentrated form of ecstasy, but users don’t always know if it’s truly “pure.” Like all synthetic drugs, it could be diluted with other psychogenic substances.

Molly is short for “molecule”. Any drug that is purchased on the street is always subject to being maned something different. According to the National Institute for Drug Abuse (NIDA). An estimated 11 million Americans have used ecstasy at least once in their lives. The drug can be adulterated with other chemicals like bath salts, a relatively new synthetic powder that often contains amphetamine-like chemicals.

MDMA is a Schedule I controlled substance. This indicates the Drug Enforcement Administration (DEA) recognizes it as having no medical use and a high potential for misuse or addiction. As a result, it’s illegal to sell, buy, or use any form of MDMA — including molly — in the United States. There are also potent designer cathinone stimulants known by the street name “bath salts,” often marketed as molly. People taking these substitutes have solid cravings and much more violent reactions.

How Long Does Molly Last
People who use MDMA usually take it as a capsule or tablet, though some swallow it in liquid form or snort the powder. 

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How Long Does Molly Effects Last?

The main effects of Molly last around 3 hours, and minor effects last around 7 hours – assuming your substance contains pure MDMA.

If you’re a new user taking Molly on an empty or mostly empty stomach, you should notice the Molly kick in around 1 hour after ingestion – experienced users who are familiar with the effects may notice it kick in after as little as 30 minutes.

The primary effects of Molly last for about 3 hours, generally from hours 1 to 4 after ingestion. You will likely feel some effects for about 7 hours, from roughly 30 minutes after ingestion until around 7-8 hours after ingestion.

A substantial portion of Molly/Ecstasy sold as MDMA isn’t really MDMA, and so if you’re experiencing different timing than described here, you may not have real MDMA.

Over the course of the week following moderate use of the drug, a person may experience:

  • Irritability
  • Impulsiveness and aggression
  • Depression
  • Sleep problems
  • Anxiety
  • Memory and attention problems
  • Decreased appetite
  • Decreased interest in and pleasure from sex

It’s possible that some of these effects may be due to the combined use of MDMA with other drugs, especially marijuana.

How Long Does Molly Last
 How long does Molly last in the human body and what are the after-effects of using Molly are questions that many misusers of the drug may have.

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Factors that Affect How Long Molly is in Your System

There are plenty of other factors that can also influence how long molly stays in your system, including how much of it is taken, how often it’s taken, and the individual’s metabolism.

  • Dosage and frequency of use: When taken in larger doses or multiple doses are taken over time, MDMA can last longer in the body. Similarly, first-time users may have a shorter detection window for ecstasy than long-time users.
  • Body type: Many drugs tend to build up in fatty tissue, meaning that people with a high body mass index (BMI) or more body fat may take longer to eliminate the drug from their systems.
  • Metabolism: A person’s metabolism can be affected by age, level of physical activity, and other health conditions. The higher the metabolism, the shorter the detection window for ecstasy.
  • Other health concerns: Other underlying health conditions such as liver and kidney disease can also impact how quickly a person metabolizes MDMA. Because these two organs are mainly responsible for flushing toxins out of the body, a person with conditions in these areas may struggle to metabolize molly.

How Long Does Molly Last in Your System?

Generally, Molly stays in a person’s system for several days. Molly enters the bloodstream very quickly after you use it. However, even after its effects wear off, traces of the drug will stay in your system. 

Molly may stay in your system for up to five days. Since tolerance also increases with use, if you use Molly chronically, it may be detectable in your system for up to a week after your last use. Higher doses may be detectable in your system for longer.

Although it’s not one of the five drugs tested by the standard five-panel drug test most employers use, molly can show up on a drug test.

Detection times for how long ecstasy lasts in your system:

  • Blood: An MDMA (molly) drug test can detect molly in the blood for 1 to 2 days after it’s taken.
  • Urine: Ecstasy (molly) can be detected in urine for 2 to 4 days after it’s taken.
  • Hair: Like other drugs, molly can be detected in hair follicles for several months.

The way it’s used also affects how long molly/MDMA stays in your system and its detection window. The faster it’s absorbed into the bloodstream, the shorter the detection window. For instance, when compared to oral ingestion, molly will stay in the body for a shorter amount of time when it’s snorted.

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What is Molly Withdrawal?

Molly is extremely psychologically addictive. Those addicted to molly will experience withdrawal when they quit using the drug. Withdrawal happens because the user’s brain becomes dependent on ecstasy to function.

Taking molly increases the activity of neurotransmitters—specifically those that influence feelings of happiness and love—in the brain. This causes the euphoric high and positive emotions associated with using molly. However, this increase in activity also quickly depletes the brain’s supply of the chemicals needed to feel this way.

After prolonged use, the user’s brain can become dependent on molly to function and experience these positive feelings. When someone quits taking the drug, they’ll go through withdrawal as their brain tries to relearn how to operate properly without it. During withdrawal, users typically experience the opposite of what they felt while high, like depression and anxiety. They’ll also intensely crave the drug.

The symptoms of molly withdrawal tend to be primarily psychological, but some users experience physical effects as well. The symptoms and duration of withdrawal vary by person. Some of the things that affect the withdrawal process include:

  • Tolerance
  • The frequency and duration of drug use
  • Metabolism and overall health
  • Age
  • Gender
  • Genetics

A user who has multiple addictions may also have a more intense and complicated withdrawal, and a user who has co-occurring mental health disorders may also experience additional challenges.

Symptoms of Withdrawal from Molly

Withdrawal from molly can produce serious psychological symptoms and some users may experience physical discomfort. However, the physical effects are typically mild and not life-threatening. Molly withdrawal symptoms may include:

  • Depression
  • Confusion
  • Anxiety
  • Cravings
  • Agitation
  • Paranoia
  • Insomnia
  • Fatigue
  • Difficulty concentrating
  • Loss of appetite
  • Memory problems
  • Changes in self-perception

Molly is often cut with other drugs, such as heroin, ketamine, amphetamines, and other illicit drugs. In many cases, molly is also taken alongside other drugs, such as cocaine or LSD. Because it’s hard to know what’s in a pill of ecstasy and so many users tend to combine it with other drugs, withdrawal symptoms are often different for each person.

Relapse during the molly withdrawal process is especially dangerous because the user’s tolerance has decreased. If they jump back into using the same amount of molly, they’re at an increased risk of overdose—which can be fatal.

Managing the symptoms of withdrawal from molly—especially the feelings of depression, which are often severe—can be difficult for a person to do on their own. It is recommended that users complete the withdrawal process in a medical detox facility or an inpatient rehab.

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Treatment for Molly Withdrawal or Addiction

Medical detox offers the safest and most effective means of withdrawal. It provides a stable and safe environment where molly can process out of the body while helping the individual reach a physical and psychological level of stability before continuing on in treatment.

Withdrawal from molly is not typically considered to be physically life-threatening as withdrawal from other drugs and alcohol may be. However, this is not to say that the side effects may not be intense and significant. Anxiety, insomnia, and depression can be particularly difficult, and a medical detox program can help to manage these symptoms of ecstasy withdrawal.

In a medical detox program, individuals are admitted to a specialized facility that provides medical and mental healthcare and supervision 24 hours a day, seven days a week. The environment is calm and secure, and individuals are encouraged and supported around the clock. Relapse and cravings can be minimized through supportive care and therapeutic methods.

Currently, there are no specific medications approved to treat molly dependence or withdrawal. However, different pharmacological tools may be helpful in managing specific symptoms. For instance, sleep aids may help to combat insomnia, and this can be essential as a healthy amount of sleep enhances healing. In a similar fashion, antidepressant medications may help to replenish serotonin and/or dopamine levels in order to manage depression and anxiety.

Individuals who have abused ecstasy on a long-term basis often suffer from lost appetite, malnutrition, and even possible weight loss or anorexia. Nutritional deficits can be rectified via regular, healthy, and balanced meals that are provided in a professional detox program.

Dehydration can be a result of ecstasy abuse, and this can be addressed with increased fluids during detox. When a person is well-rested and nutritionally balanced, they are more able to think clearly and make better decisions; thus, they are better equipped to avoid relapse.

Medical detox programs generally last 5-7 days. While they are an essential component of recovery, further treatment is needed. Ideally, clients progress directly from medical detox into a comprehensive addiction treatment program.

How long does Molly last in the human body and what are the after-effects of using Molly are questions that many misusers of the drug may have. If you feel that you may have developed a substance use disorder involving Molly/Ecstasy/MMDA, help is available. Contact We Level Up to learn more about addiction treatment today.

how long does molly last
It is difficult to determine exactly how long molly will stay in a person’s system. It depends on many factors. Molly affects the brain by increasing the activity of three brain chemicals: serotonin, dopamine, and norepinephrine.

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[1] NIDA –

[2] DEA –