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What are Trazodone Side Effects? Interactions with Alcohol

Drinking alcohol while taking Trazodone can be dangerous. Trazodone side effects may amplify the effects of alcohol, leading to an overdose. Continue to read more about Trazodone and alcohol interactions and Trazodone side effects.

By We Level Up NJ Treatment Center | Editor Yamilla Francese | Clinically Reviewed By Lauren Barry, LMFT, MCAP, QS, Director of Quality Assurance | Editorial Policy | Research Policy | Last Updated: December 8, 2022

Trazodone and Alcohol Interactions, Trazodone Side Effects

Mixing trazodone with alcohol can increase levels of intoxication and heighten trazodone side effects, resulting in extreme drowsiness and increasing the risk of overdose and death when consumed excessively. Long-term use of both substances can also lead to physical dependence and withdrawal.

Trazodone is a medication used to treat depression. Unfortunately, a growing trend among antidepressant users is combining them with alcohol to create a sedative or relaxing effect.

What is Trazodone?

Trazodone is an FDA-approved antidepressant for treating major depressive disorders. Brand names- Desyrel, Trittico, Oleptro, Molipaxin, Trazorel (among others). It is a prescription drug that can be used as part of combination therapy with other medications or psychotherapies or for treating depression. Non-FDA-approved use induces sedation in patients with sleep problems and anxiety. These patients may or may not have concurrent depression or anxiety. Trazodone is not FDA-approved for sleep disorders because it lacks sufficient clinical data to justify its use as a sleep aid. Trazodone mixed with alcohol can lead to severe side effects that affect a person’s overall health.

Long-term use of Trazodone and alcohol may result in physical dependence and withdrawal symptoms.
Long-term use of Trazodone and alcohol may result in physical dependence and withdrawal symptoms.

Because of its serotonergic receptor antagonism and serotonin reuptake inhibiting effects, Trazodone is also used off-label for Alzheimer’s disease, anxiety, substance abuse, fibromyalgia, and bulimia. Trazodone has also been used for post-traumatic stress disorder (PTSD) if the first-line treatment use of SSRIs does not show efficacy. The dose of 50 mg to 200 mg of Trazodone has been demonstrated to reduce episodes of nightmares as well as improve sleep habits in studies involving PTSD patients.

Do not use this medicine if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could happen. MAO inhibitors include linezolid, isocarboxazid, methylene blue injection, phenelzine, tranylcypromine, and others. Tell your doctor if you also take opioid medicine, stimulant medicine, herbal products, or medicine for mental illness, depression, Parkinson’s disease, migraine headaches, serious infections, or prevention of nausea and vomiting.

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Trazodone and Alcohol Statistics

More than 20 million people in the United States have had a substance use disorder. Substance use disorders can involve illicit drugs, prescription drugs, or alcohol. Unfortunately, many are also mixing drugs with alcohol. Effective treatments for substance use disorders are available, but very few people get the treatment they need. Strategies to prevent substance use and help people get treatment can reduce drug and alcohol misuse, related health problems, and deaths.


6%

6% of Americans over 12 abuse prescriptions each year.

Source: CDC

12%

12% of prescription drug abusers are addicted.

Source: CDC

5,000

Over 5,000 people ages 65 and over in the U.S. died of a drug overdose in 2020, and more than twice that many (11,616) died of alcohol-induced causes. 

Source: CDC


Trazodone and Alcohol Facts Sheet

Alcohol can increase the nervous system side effects of trazodone such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. You should avoid or limit the use of alcohol while being treated with trazodone. 


It’s best to avoid combining antidepressants and alcohol. It may worsen your symptoms, and it can be dangerous. If you mix antidepressants and alcohol:

  • You may feel more depressed or anxious. Drinking can counteract the benefits of your antidepressant medication, making your symptoms more difficult to treat. Alcohol may seem to improve your mood in the short term, but its overall effect increases symptoms of depression and anxiety.
  • Side effects may be worse if you also take another medication. Many medications can cause problems with alcohol, including anti-anxiety, sleep, and prescription pain medications. Side effects may worsen if you drink alcohol and take one of these drugs with an antidepressant.
  • Your thinking and alertness may be impaired. The combination of antidepressants and alcohol will affect your judgment, coordination, motor skills, and reaction time more than alcohol alone. Some combinations may make you sleepy. This can impair your ability to drive or do other tasks that require focus and attention.
  • You may become sedated or feel drowsy. A few antidepressants cause sedation and drowsiness, and so does alcohol. When taken together, the combined effect can be intensified.

What is Trazodone Used for?

Trazodone is an antidepressant that inhibits serotonin type 2 receptors and serotonin transporter. It is a triazolopyridine derivative. Trazodone inhibits the reuptake of serotonin and blocks the histamine and alpha-1-adrenergic receptors. It also induces significant changes in 5-HT presynaptic receptor adrenoreceptors. The Trazodone category is of SARI drugs (serotonin antagonists and reuptake inhibitors), with other members being etoperidone, phenylpiperazine, lorpiprazole, and mepiprazole.

Trazodone administration is via the oral route. It may be taken after meals to decrease postural hypotension and lightheadedness. Trazodone may be available as immediate-release (IR) tablets, prolonged-release tablets, and in some cases, injection and oral drops solutions. It can take one to two weeks before trazodone starts to work, but maybe four to six weeks before you feel the full benefit.

Can you take Trazodone for anxiety attack? Trazodone can also include treatment for the effects of alcohol withdrawal, anxiety treatment, medications for schizophrenia treatment, and uncontrolled movements resulting from side effects from other medications. Trazodone for pain is also frequent off-label use of drugs, and in particular, it can be helpful for chronic pain conditions like fibromyalgia. Individuals with chronic pain are often given antidepressants and medications that control the pain. This is because of chronic pain’s effects on mood and the likelihood of developing depression.

Trazodone should not be used in patients with a history of heart disease or a recent heart attack. This medication can cause or worsen QT prolongation (a disorder of the heart), which can cause an irregular heart rhythm that can lead to seizures, fainting, or even death.

Is Trazodone a Narcotic?

Trazodone is not a narcotic. Narcotics are opioids—drugs that relieve pain by blocking the pain receptors in your brain. Trazodone is an antidepressant medication that alters brain chemicals called neurotransmitters to help ease depression.

Trazodone is it a Controlled Substance?

While trazodone is not a narcotic or a controlled substance, specific research on the abuse potential of trazodone is lacking. Clinical trials of trazodone did not show any signs of drug-seeking behavior. Trazodone is intended for use in people with depression. However, trazodone is often prescribed off-label for other conditions, such as insomnia, and the drug’s abuse potential has not been studied for these uses.

Trazodone for Sleep Disorder

Trazodone is not classified by the FDA as a controlled substance, unlike medications such as Lunesta and Ambien. This means that Trazodone is not considered to have potential abuse and misuse. Because trazodone is not classified as a controlled substance, doctors do not have strict limits on how many pills they’re able to prescribe.

Trazodone for sleep disorder treatment medication has the advantage of being an effective treatment for insomnia. Trazodone is helpful at low doses for primary and secondary insomnia. Moreover, it is less expensive than some newer insomnia medications due to its availability. At low doses, trazodone as a sleep aid is often very effective for insomnia.

Trazodone PTSD

Post-traumatic stress disorder, a psychiatric disorder, arises following exposure to perceived life-threatening trauma. Its symptoms can mimic those of anxiety or depressive disorders. Current treatment strategies combine patient education and pharmacologic interventions, such as selective serotonin reuptake inhibitors, trazodone and clonidine, and psychotherapy. 

Trazodone (Desyrel) at 50 to 200 mg has SSRI properties and serotonin blockade action. It reverses SSRI-induced insomnia; augments the antidepressant effects of SSRIs; promotes sleep through its sedative properties, and suppresses rapid eye movement sleep, thus reducing the nightmares associated with PTSD.

Trazodone and alcohol addiction is possible, but it’s not as common as other types of drug addiction. 
Trazodone and alcohol addiction is possible, but it’s not as common as other types of drug addiction. 

Dose of Trazodone 

Before prescribing Trazodone, your doctor will ask you if you have any allergies and what other medications you are taking. This ensures that the Trazodone will not cause an allergic reaction or interact with the other drugs. You must mention if you or they have heart, kidney, or liver disease, blood pressure problems, or a history of glaucoma or substance abuse.

As Trazodone can cause dizziness, drowsiness, and blurred vision, your doctor will advise you not to drive or use machinery until these symptoms pass. If you smoke marijuana, you should tell your doctor. Can you drink on trazodone? Smoking marijuana or drinking alcohol can increase dizziness which is sometimes experienced when taking Trazodone.

According to the Food and Drug Administration (FDA), dosing should be as follows:

  • For the treatment of depression, a usual starting dose is 150 milligrams (mg) per day. When the regular tablets are taken, this would most likely be scheduled as 75 mg in the morning and 75 mg at night.
  • For the treatment of insomnia, the dose is usually started at 25 to 50 mg at night.

Your healthcare provider will then work with you to find the correct dose and may increase your dose every few days. Check your prescription and talk to your healthcare provider to ensure you take the correct dose.

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Is Trazadone Addictive?

Trazodone is addictive or habit-forming, but not in the same way that drugs like cocaine, meth, or heroin are. Rather than an all-consuming physical addiction, a person who abuses trazodone may develop a physical dependence on it and a psychological addiction to it.

Dependence on this drug is marked by withdrawal symptoms of Trazodone when the person reduces their dosage or ceases use completely. Alongside dependence, a person may also develop a psychological addiction to trazodone, in which they might feel they have to use it to feel normal or be happy.

Does Trazodone Get You High?

Although trazodone cannot get you high in the same way drugs as opioids or stimulants can, it can have sedative effects. Despite the lack of euphoria in a trazodone high, the medication produces a relaxing and calming effect that users might find desirable. Trazodone abuse can occur in people to whom it’s been prescribed and in people who take it for trazodone recreational purposes.

Trazodone Side Effects

Trazodone may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

  • Nausea
  • Vomiting
  • Diarrhea
  • Constipation
  • Changes in appetite or weight
  • Weakness or tiredness
  • Nervousness
  • Dizziness or lightheadedness
  • Nightmares
  • Muscle pain
  • Dry mouth
  • Rash
  • Sexual problems in males; decreased sex drive, inability to get or keep an erection, or delayed or absent ejaculation.
  • Sexual problems in females; decreased sex drive, delayed orgasm, or inability to orgasm.
  • Uncontrollable shaking of a part of the body
  • Stuffy nose
  • Tired, red, or itchy eyes

Some side effects can be severe. If you experience any of the following symptoms, call your doctor immediately or get emergency medical treatment:

  • Chest pain
  • Fast, pounding, or irregular heartbeat
  • Loss of consciousness (coma)
  • Fever, sweating, confusion, fast or irregular heartbeat, severe muscle stiffness or twitching, agitation, hallucinations, loss of coordination, nausea, vomiting, or diarrhea
  • Fainting
  • Seizures
  • Shortness of breath
  • Unusual bruising or bleeding
  • Nosebleeds
  • Small red or purple dots on the skin
  • Erection lasting more than 6 hours
  • Headache
  • Problems with thinking, concentration, or memory
  • Weakness
  • Problems with coordination

What are the Long-Term Side Effects of Trazodone?

While trazodone is generally safe and effective when used as prescribed for its intended purpose, an individual who abuses trazodone for extended periods may be at risk of experiencing more intense side effects, long term effects trazodone may include:

  • Decreased serum sodium levels (hyponatremia) and associated symptoms (headache, concentration problems, memory problems, confusion, weakness, instability, increased fall risk)
  • Serotonin syndrome
  • Angle-closure glaucoma
  • Blurred vision
  • Confusion
  • Hypotension
  • Fainting
  • Coordination problems
  • Gastrointestinal upset
  • Tremors
  • Heart rate and rhythm abnormalities

Trazodone Off Label Uses

Other, not officially approved (off-label) uses of trazodone include the treatment of bulimia, benzodiazepine, and alcohol dependence or abuse, fibromyalgia, degenerative diseases of the central nervous system such as dementia and other organic disorders, schizophrenia, chronic pain, and diabetic neuropathy [3]. Few clinical trials have been conducted to evaluate trazodone’s efficacy in treating the diseases and symptoms for which it is often used in clinical practice. More studies are necessary to investigate possible new therapeutic indications and to scientifically demonstrate the risk/benefit ratio for the many conditions for which trazodone is used but not approved by the FDA.

Trazodone Side Effects Hallucinations

Can trazodone cause hallucinations? According to the National Center for Biotechnology Information [4], there was a case of a 60-year-old man who received trazodone for primary insomnia. Two days later, he returned to the emergency department with distressing visual hallucinations, which prompted inpatient treatment. Trazodone was discontinued, leading to a complete resolution of his visual hallucinations.

Hallucinations are sensory perceptions that occur without an external stimulus in any sensory modality. Visual Hallucinations are more common in acute organic states with clouding of consciousness and patients with neurodegenerative disorders. We report a case of trazodone-induced visual hallucinations that, to our knowledge, is the first described in the literature.

Although trazodone side effects and overdose is less common, it can happen when you mix alcohol and the drug.
Although trazodone side effects and overdose are less common, those side effects can happen when you mix alcohol and the drug.

Trazodone Interactions 

While a trazodone high isn’t a reported effect with this drug, however, if you mix it with other substances, it can amplify the effects of those. For example, if you combine trazodone and alcohol, it can increase your responsiveness to the alcohol. This can occur with any type of central nervous system depressant, so it’s important to let your doctor know of any other substances you use before taking trazodone.

Taking MAO inhibitors with this medication may cause a serious (possibly fatal) drug interaction. Avoid taking MAO inhibitors (isocarboxazid, linezolid, metaxalone, methylene blue, moclobemide, phenelzine, procarbazine, rasagiline, safinamide, selegiline, tranylcypromine) during treatment with this medication. Most MAO inhibitors should also not be taken for two weeks before and after treatment with this medication. 

Can Trazodone Cause Serotonin Syndrome?

Trazodone may cause a serious condition called serotonin syndrome if taken with some medicines. Do not use trazodone with buspirone, fentanyl, lithium, tryptophan, St. John’s wort, or some pain or migraine medicines. Serotonin syndrome is a rare but potentially life-threatening adverse drug reaction resulting from the use or overuse of serotonergic medications alone or in combination. The major reasons for an often missed diagnosis are mild symptoms, overlapping features with similar conditions, and clinician lack of awareness. Serotonin syndrome is potentially deadly [5].

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Serotonin Syndrome

The serotonin syndrome/toxicity risk increases if you also take other drugs that increase serotonin. Examples include street drugs such as MDMA/”ecstasy,” certain antidepressants (including SSRIs such as fluoxetine (Prozac), and SNRIs such as duloxetine/venlafaxine), among others. The serotonin syndrome/toxicity risk may be more likely when you start or increase the dose of these drugs.

Clinical symptoms of serotonin syndrome can develop within two hours—or up to 24 hours—after taking an increased dose or adding another serotonergic drug.

Signs and symptoms of serotonin syndrome:

  • Tremors
  • Muscle aches
  • Sweating
  • Anxiety
  • Confusion
  • Tachycardia
  • Delirium
  • Hallucinations
  • Seizures
  • Renal failure
  • Death

Trazodone and Alcohol

Can you drink with Trazodone? Drinking alcohol while taking trazodone can be dangerous. Trazodone may amplify some of the effects of alcohol, which can lead to dangerous levels of intoxication and even overdose and trazodone and alcohol death. The combination can also cause extreme drowsiness, leading to accidents and injuries. In addition, alcohol can increase the risk of depression, anxiety, and other mental health problems such as anxiety disorders, depression, and suicidal thoughts. Some users who have mixed trazodone with alcohol claim the combination impairs their thinking and judgment. Alcohol is a depressant, and combining an antidepressant with a depressant can lead to unpredictable and dangerous consequences for different users.

Trazodone Interactions with Alcohol

What are the signs of trazodone and alcohol interactions? Trazodone has a possibility for physical dependence when consumed with alcohol. Drinking 50mg of trazodone and alcohol is no exception. Furthermore, this deadly combination can lead to delirium, hallucinations, and seizures in extreme cases. Trazodone alcohol interaction can lead to severe side effects that affect a person’s overall health.

As mentioned, trazodone 50 mg and alcohol can amplify each other’s effects. Since both agents are central nervous system depressants, taking them together can be risky due to additive side effects from their drug interactions, which include:

  • Difficulty concentrating
  • Impairment in thinking and judgment
  • Dramatic mood swings
  • Increased depression or anxiety
  • Dizziness
  • Increased intoxication
  • Drowsiness
  • Confusion
  • Fainting

Trazodone and Alcohol Withdrawal

Long-term use of alcohol and trazodone can also lead to the development of physical dependence and withdrawal symptoms. Trazodone alcohol withdrawal symptoms can include agitation, anxiety, and sleep problems. Instead of coming off Trazodone cold turkey, people on the medication are advised to be tapered or gradually weaned off under the care of a physician.

Severe alcohol withdrawal syndrome can be pretty serious. It can include symptoms such as alcohol-induced insomnia, increased body temperature, anxiety, rapid pulse, sweating, nausea, and vomiting, as well as more severe complications such as hallucinations or alcohol-induced psychosis, agitation, delirium, and seizures. Left unmanaged, alcohol withdrawal can even be life-threatening due to the possibility of grand mal seizures.

Individuals who have become dependent on alcohol and Trazodone may need medically-supervised withdrawal management and detox—either as part of a standalone program or at the start of a rehabilitation program. Medical-supervised detox programs are staffed with healthcare professionals who can monitor the individual’s recovery during withdrawal and provide therapeutic interventions when needed.

Trazodone Withdrawal

What is withdrawal? Withdrawal is the body’s process of readjusting to the absence of a drug in its system. For example, after a consistent amount of time taking the drug, the brain and body become used to trazodone and adapt to its presence. Can you have withdrawals from trazodone? If you suddenly quit taking trazodone, you may feel ill as your body readjusts after the change in routine. Trazodone withdrawal can be very challenging for people attempting to stop trazodone.

Attempting to manage the withdrawal symptoms of Trazodone without medical supervision can be dangerous. This is especially true if you take trazodone to treat mood issues like depression, which may worsen if you suddenly quit the drug.

Withdrawal Symptoms from Trazodone

When an individual is going through Trazodone withdrawal symptoms, discomfort is common. Other physical symptoms associated with trazodone withdrawals include:

  • Agitation
  • Anxiety
  • Confusion
  • Dizziness
  • Headache
  • Trouble sleeping
  • Irritabilitytrazodone withdrawal

Since trazodone is often prescribed to treat mental health issues like depression, there are adverse effects when abruptly stopping use. Individuals who struggle with depression and take trazodone for treatment may feel increased depression during Trazodone withdrawal. For this reason, it is important only to stop taking trazodone under a doctor’s care.

How Long Does Trazodone Withdrawal Last? Trazodone Withdrawal Timeline

Everyone experiences trazodone withdrawal symptoms differently. For some individuals, physical symptoms could subside in just a few days. For others, they could last weeks or longer. When individuals experience withdrawal from antidepressant medications such as trazodone, various factors influence the duration of trazodone withdrawal and the intensity of symptoms. These include:

  • How long has the individual been taking trazodone
  • Dosage amount before starting trazodone withdrawal
  • Individual characteristics

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Treatment for Trazodone Side Effects and Alcohol Abuse 

To determine the most effective ways to treat Trazodone side effects and co-occurring alcohol addiction, it’s crucial to assess all the symptoms accurately. When a mental health professional has evaluated the symptoms, it may be determined that another form of depression is present and needs a particular treatment. Very often, some combination of medication, psychotherapy, and lifestyle changes are effective for coping with functional.

Medically-Assisted Detox

Detox is often considered the first stage of treatment. It will help you navigate the complicated process of alcohol withdrawal but doesn’t address patterns of thought and behavior that contribute to alcohol use. Various treatment approaches and settings can help provide the ongoing support necessary to maintain long-term sobriety after you complete detox.

Cravings are pervasive side effects of Trazodone during detox and can be challenging to overcome. This often leads to relapse. Constant medical care provided during inpatient treatment helps prevent relapse. Clinicians can give the necessary medication and medical expertise to lessen cravings and the effects of alcohol withdrawals.

Psychotherapy for Depression

Several different modalities of psychotherapy have been used in the treatment of depression, including:

  • Cognitive Behavioral Therapy (CBT) – is an effective treatment that involves changing both the patterns of negative thoughts and the behavioral routines which are affecting the daily life of the depressed person for various forms of depression.
  • Person–centered therapy is a strategy that allows and encourages clients to understand and resolve their concerns in a safe, supportive environment.
  • Solution Focused Therapy – an approach interested in solutions that can be quickly implemented with a simple first step leading to further positive consequences.

Dual Diagnosis Treatment

Alcoholism and mental health disorders often co-occur. In many cases, traumatic experiences can result in mental health disorders and substance abuse. Dual diagnosis rehabilitation treats both of these issues together. The best approach for the treatment of dual diagnosis is an integrated system. This strategy treats both the substance abuse problem and the mental disorder simultaneously. Regardless of which diagnosis (mental health or substance abuse problem) came first, long-term recovery will depend largely on the treatment for both disorders done by the same team or provider.

Medication-Assisted Treatments

Medication-Assisted Treatments (MAT) for alcohol use and mental health disorders are commonly used in conjunction with one another. This includes the use of medications and other medical procedures. During your rehab, the staff from your treatment facility will help you identify what caused your addiction and teach you skills that will help you change your behavior patterns and challenge the negative thoughts that led to your addiction. Sometimes, the pressures and problems in your life lead you to rely on substances to help you forget about them momentarily.

Contact one of our helpful treatment specialists today if you or a loved one are struggling with long-term substance abuse, Trazodone side effects, and other co-occurring mental health conditions such as depression. We Level Up NJ can provide information on dual diagnosis and detox programs.

Therapists specializing in substance use can help clients identify the underlying causes of substance abuse. Looking for treatment for trazodone side effects and alcohol abuse? Contact We Level Up New Jersey for the resources.
Therapists specializing in substance use can help clients identify the underlying causes of substance abuse. Looking for treatment for trazodone side effects and alcohol abuse? Contact We Level Up New Jersey for the resources.

Top 5 Most Trazodone and Alcohol Frequently Asked Questions

  1. Can you mix trazodone and alcohol?

    Drinking alcohol while taking trazodone can be dangerous. Trazodone may amplify some of the effects of alcohol, which can lead to dangerous levels of intoxication and even overdose and death. The combination can also cause extreme drowsiness, leading to accidents and falls.

  2. What are the risks of combining trazodone Xanax and alcohol?

    You can theoretically take Xanax and trazodone together, but you might experience heightened side effects of one or both. For example, you might experience confusion, dizziness, and coordination and concentration problems if you take Xanax and trazodone together. These side effects of the two drugs combined can be worst with alcohol.

  3. Is it safe mixing trazodone and alcohol?

    No. The combination of trazodone and alcohol will affect your judgment, coordination, motor skills, and reaction time more than alcohol alone. Some combinations may make you sleepy. This can impair your ability to drive or do other tasks that require focus and attention. You may become sedated or feel drowsy.

  4. How does trazodone help with alcohol dependence?

    Trazodone, a second-generation antidepressant, is helpful in the treatment of lasting alcohol withdrawal symptoms, such as sleep disturbances and cravings. But mixing them is not advisable and can only lead to adverse effects.

  5. Can I take trazodone 2 hours after drinking?

    When taking antidepressants, you should not drink alcohol at all. Trazodone may amplify some of the effects of alcohol, which can lead to dangerous levels of intoxication and even overdose and death.

List of Popular Trazodone Side Effects FAQs

Is trazodone an opiate?

No. Trazodone is in a class of medications called serotonin modulators. It works by increasing the amount of serotonin, a natural substance in the brain that helps maintain mental balance.

Can you take trazodone after drinking?

Drinking alcohol with trazodone is not recommended. What happens if you take trazodone with alcohol? For one, it can worsen trazodone’s side effects, such as drowsiness or blurred vision.

Can you drink alcohol with trazodone?

Can you take trazodone with alcohol? Drinking alcohol while taking trazodone can be dangerous. Trazodone may amplify some of the effects of alcohol, which can lead to dangerous levels of intoxication and even overdose and death. Drinking on trazodone can be risky.

Can you get high off trazodone?

Although trazodone cannot get you high in the same way drugs as opioids or stimulants can, it can have sedative effects.

Is Trazodone and Xanax the same thing?


No. You might experience the same side effects while taking Xanax or trazodone, but the two drugs belong to different medication classes. Trazodone is a selective serotonin reuptake inhibitor (SSRI), while Xanax is a benzodiazepine.

Can trazodone cause seizures?

Epileptic seizures were reported because of high-dose trazodone use. The abuse of trazodone and seizures are interconnected.

How to get off trazodone?

Tapering use or detoxing from trazodone under medical supervision can help ease you off the drug and minimize withdrawal symptoms.

How many trazodone can you take for sleep?

When prescribed for sleep, trazodone can be taken in several doses: The starting dose is usually 50 mg to 100 mg at bedtime. If needed, the dose can be increased to 200 mg at bedtime. Please consult your doctor.

Can you abuse Trazadone?

Sadly, the recreational use of trazodone is on the rise. Although it doesn’t cause euphoria, the drug produces a relaxing, calming effect that users find desirable. Recreationally, trazodone is called by the street name “sleepeasy.”

Can you take trazodone with Wellbutrin?

Combining trazodone and Wellbutrin may increase the risk of seizures, which may rarely occur with either medication.

How long does trazodone last in your system?

Trazodone’s half-life is 5–9 hours, meaning it will take about 25–45 hours for trazodone to be out of the system.

Does trazadone cause dry mouth?

Trazodone may cause dry mouth. Use sugarless gum or candy, melt bits of ice in your mouth, or use a saliva substitute for temporary relief. 

Can you take Zoloft and trazodone together?

Using Trazodone together with Zoloft can increase the risk of a rare but serious condition called serotonin syndrome, which may include symptoms such as confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking.

Can you take trazodone with oxycodone?

Using trazodone and oxycodone can increase the risk of a rare but serious condition called serotonin syndrome, which may include symptoms such as confusion, hallucinations, seizures, extreme changes in blood pressure, and increased heart rate. Taking oxycodone and trazodone for recreational purposes is risky.

Do trazodone side effects go away?

Some Trazodone common side effects may go away during treatment as the body adjust to the medicine.

How to get trazodone out of your system fast?

After a single dose in a healthy adult, trazodone will be mostly out of your system in one to three days. For trazodone the half-life is approximately 5 to 13 hours.

Is Trazodone addictive?

Trazodone is addictive or habit-forming, but not in the same way that drugs like cocaine, meth, or heroin are.

What are trazodone benefits?

This medication is used to treat depression. It may help to improve your mood, appetite, and energy level and decrease anxiety and insomnia related to depression.

What are the long term side effects of trazodone?

Regarding trazodone long term effects, it’s considered a relatively safe substance. There aren’t currently believed to be any serious trazodone long-term effects on the brain from repeated use, which is one of the reasons it is preferred over other antidepressants and sleep aids in some cases.

What are the side effects of trazodone 150 mg?

Like all medicines, trazodone can cause side effects, although not everybody gets them.

Talk to your doctor straight away if you notice the following side-effects:

  • You have thoughts of harming or killing yourself
  • Feeling tired, faint, dizzy, and having pale skin. These could be signs of anemia
  • Convulsions/fits
Can you take Percocet and trazodone together?

Using Percocet and trazodone together can increase the risk of a rare but serious condition called serotonin syndrome, which may include symptoms such as confusion, hallucinations, seizures, extreme changes in blood pressure, increased heart

What are the side effects stopping trazodone?

Trazodone withdrawal side effects may include agitation or irritability, sleep disturbances or insomnia, anxiety, depression, mood swings, sweating, nausea, or digestive upset.

What are the effects of stopping trazodone cold turkey?

If you’ve become dependent on trazodone, speak to your doctor before stopping Trazodone cold turkey. Side effects of stopping trazodone cold turkey after a period of dependence may cause more intense and uncomfortable withdrawal symptoms. 

What is trazodone side effects muscle pain?

Muscle aches and pains are a well-recognized possible side-effect of Trazodone. An irregular heartbeat is also a possible side effect.

What are the most common side effects of trazodone?

Summary Commonly reported side effects of trazodone include: blurred vision, dizziness, drowsiness, headache, nausea, vomiting, and xerostomia. Other side effects include: syncope, edema, ataxia, confusion, diarrhea, hypotension, insomnia, sedated state, and tachycardia.

What are the effects of the interactions of trazodone and wine?

The use of alcohol with trazodone will increase the effects of the medication making you more dizzy and drowsy. Drinking wine while on this medication or any other medication is not recommended.

Is Trazodone a benzo?

No. You might experience some of the same side effects while taking a bezo or trazodone, but the two medications belong to different medication classes. 

What are Xanax and trazodone high?

Since both Xanax and trazodone have the potential for abuse, addiction, and dependence, the risk of these scenarios occurring may be higher if you take both together as well.

What are the psychological effects of trazodone?

Behavior or mood changes (eg, aggression, panic attacks) or. Bipolar disorder (mood disorder with mania and depression)

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