Trazodone Side Effects, Females vs. Males Sexually, in the Elderly, Long-term, Weight-gain, Trazodone and Alcohol Risks
Drinking alcohol while taking Trazodone can be dangerous. Trazodone side effects may amplify the effects of alcohol, leading to an overdose. Continue to read more about Trazodone and alcohol interactions and Trazodone side effects.
By We Level Up NJ Treatment Center | Editor Yamilla Francese | Clinically Reviewed By Lauren Barry, LMFT, MCAP, QS, Director of Quality Assurance | Editorial Policy | Research Policy | Last Updated: March 23, 2023
Trazodone Side Effects
Trazodone side effects can occur like all medications. Trazodone is commonly used to treat depression, anxiety disorders, and insomnia. Trazodone is a medication that belongs to a class of drugs called serotonin modulators.
Common Side Effects of Trazodone include:
- Dizziness or lightheadedness.
- Drowsiness or sedation.
- Nausea or vomiting.
- Dry mouth.
- Blurred vision.
- Muscle aches or pain.
Less common Side Effects of Trazodone that may require immediate medical attention include:
- Irregular heartbeat.
- Chest pain.
- Shortness of breath.
- Swelling in the extremities.
- Vision changes.
- Priapism (prolonged and painful erection).
Rare Side Effects of Trazodone
While rare, Trazodone can cause serious side effects requiring immediate medical attention. These can include:
- Suicidal thoughts or behavior: Trazodone can increase the risk of suicidal thoughts or suicidal behavior, especially in young adults and teenagers.
- Serotonin syndrome: Trazodone can cause serotonin syndrome when used with other medications that affect serotonin levels, causing symptoms such as agitation, confusion, rapid heart rate, and high blood pressure.
- Allergic reactions: Some people may experience an allergic reaction to trazodone, causing symptoms such as rash, hives, itching, swelling, dizziness, or difficulty breathing.
- Low blood pressure: Trazodone can cause a sudden drop in blood pressure, causing symptoms such as fainting, dizziness, or lightheadedness.
- Mania or hypomania: Trazodone can cause a manic or hypomanic episode in some people, characterized by racing thoughts, increased energy, and decreased need for sleep.
It’s essential to contact a healthcare provider immediately if these or other serious side effects occur while using trazodone.
What is Trazodone?
Trazodone is an FDA-approved antidepressant for treating major depressive disorders. Brand names- Desyrel, Trittico, Oleptro, Molipaxin, Trazorel (among others). It is a prescription drug that can be used in combination therapy with other medications, psychotherapies, or for treating depression. Non-FDA-approved use induces sedation in patients with sleep problems and anxiety. These patients may or may not have concurrent depression or anxiety. Trazodone is not FDA-approved for sleep disorders because it lacks sufficient clinical data to justify its use as a sleep aid.
When mixed with alcohol, Trazodone side effects can lead to severe consequences affect a person’s health.
Because of its serotonergic receptor antagonism and serotonin reuptake inhibiting effects, Trazodone is also used off-label for Alzheimer’s disease, anxiety, substance abuse, fibromyalgia, and bulimia.
Trazodone has also been used for post-traumatic stress disorder (PTSD) if the first-line treatment use of SSRIs does not show efficacy. The dose of 50 mg to 200 mg of Trazodone has been demonstrated to reduce episodes of nightmares as well as improve sleep habits in studies involving PTSD patients.
Trazodone Female Side Effects
There are multiple possible trazodone female side effects. Trazodone is an antidepressant medication commonly used to treat depression, anxiety, and insomnia. Some potential Trazodone female side effects may include:
- Drowsiness or dizziness.
- Dry mouth.
- Blurred vision. Nausea or vomiting.
- Confusion and memory problems.
- Changes in appetite or weight.
- Decreased sex drive or difficulty reaching orgasm.
- Menstrual changes or irregularities.
Talking to a healthcare provider about any trazodone female side effects and symptoms or concerns you may have is necessary. They can provide personalized advice and guidance based on your medical history and needs.
Trazodone Sexual Side Effects On Men
The most typical trazodone sexual side effects include:
- Decreased libido or sex drive
- Trazodone erectile side effects (erectile dysfunction for men)
- Difficulty achieving orgasm in both men and women
- Delayed ejaculation
- Sexual anesthesia or inability to feel sexual pleasure
- Priapism or painful, prolonged erection in men
Trazodone Side Effects Sexually Female Symptoms
Some common trazodone female side effects in females may include:
- Decreased libido or sex drive
- Difficulty achieving orgasm or delayed orgasm
- Decreased vaginal lubrication
- Painful intercourse
- Sexual anesthesia or inability to feel sexual pleasure
- Changes in the menstrual cycle or bleeding
In some infrequent cases, Trazodone side effects sexually female symptoms may induce persistent engorgement of the clitoris and vaginal erectile tissues, consistent with persistent genital arousal.
Where a female has ongoing genital arousal, it is necessary to discontinue Trazodone. In some cases of females with trazodone-induced persistent sexual arousal, discontinuation of Trazodone may lead to discontinuation of the persistent genital arousal.
Not everyone will experience Trazodone sexual side effects, which may vary from person to person. It is important to talk to your healthcare provider if you are experiencing any concerning side effects while taking trazodone. They may be able to adjust the dosage or switch you to a different medication to help manage these symptoms.
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Trazodone and Alcohol Interactions, Trazodone Side Effects
Mixing trazodone with alcohol can increase levels of intoxication and heighten trazodone side effects, resulting in extreme drowsiness and increasing the risk of overdose and death when consumed excessively. Long-term use of both substances can also lead to physical dependence and withdrawal.
Trazodone is a medication used to treat depression. Unfortunately, a growing trend among antidepressant users combines Trazodone with alcohol to create a sedative or relaxing effect.
Trazodone Side Effects Warning
Do not use this medicine if you have used an MAO inhibitor for 14 days. A dangerous drug interaction could happen. MAO inhibitors include linezolid, isocarboxazid, methylene blue injection, phenelzine, tranylcypromine, and others.
Trazodone Side Effects in Elderly
Common side effects of trazodone in elderly people include drowsiness, dizziness, blurred vision, dry mouth, constipation, and headache. Other less common side effects can include an irregular heartbeat or fainting, changes in appetite or weight gain/loss, confusion and difficulty concentrating. In rare cases agitation or hallucinations may occur.
Elderly people may be particularly sensitive to the sedative effects of trazodone. As a result they should not operate vehicles or heavy machinery until any sedation is completely gone and it is safe to do so. Trazodone should also be used with caution when taking other medications that affect blood pressure as it can cause low blood pressure (hypotension) resulting in lightheadedness and dizziness.
It is very important to notify your healthcare provider right away if any side effects occur as a result of taking trazodone. Your doctor may be able to adjust the dosage or prescribe an alternative medication more suitable for elderly people. It is also important to remember that trazodone should not be stopped abruptly, as this can lead to withdrawal symptoms such as headaches, nausea, vomiting, insomnia, sweating, confusion and irritability.
In conclusion, trazodone can help to manage depression in elderly people but it does come with risks and side effects that must be taken into consideration before beginning treatment. Talk with your doctor about any concerns you have related to taking trazodone and follow their instructions carefully. With the right precautions and communication, trazodone can be a helpful tool for managing depression in elderly people.
Trazodone and Alcohol Statistics
More than 20 million people in the United States have had a substance use disorder. Substance use disorders can involve illicit drugs, prescription drugs, or alcohol. Unfortunately, many are also mixing drugs with alcohol. Effective treatments for substance use disorders are available, but very few people get the treatment they need. Strategies to prevent substance use and help people get treatment can reduce drug and alcohol misuse, related health problems, and deaths.
6% of Americans over 12 abuse prescriptions each year.
12% of prescription drug abusers are addicted.
Over 5,000 people ages 65 and over in the U.S. died of a drug overdose in 2020, and more than twice that many (11,616) died of alcohol-induced causes.
Trazodone Side Effects Fact Sheet
Trazodone is a medication that has been widely used since the 1970s to treat depression, anxiety disorders, and insomnia. It is generally considered safe and effective. But, Trazodone side effects, may ocurr. Trazodone side effects associated with the drug including the following:
Typical Trazodone Side Effects
Typical Trazodone side effects include feeling dizzy, lightheaded, drowsy, sedated, and nauseous. Other common Trazodone side effects include vomiting, dry mouth, blurry vision, headaches, constipation, and muscle pains.
It’s vital to reacha healthcare provider if any serious trazodone side effects occur while using the medicine. Additionally, reporting trazodone side effects experienced while using the medication to a healthcare professional is crucial.
What are Trazodone Female Side Effects?
Trazodone is an antidepressant medication commonly used to treat depression, anxiety, and insomnia among women. Some of the possible Trazodone female side effects include:
- Drowsiness or dizziness
- Dry mouth
- Blurred vision
- Nausea or vomiting
- Confusion or memory problems
- Changes in appetite or weight
- Decreased sex drive or difficulty reaching orgasm
- Menstrual changes or irregularities
It is crucial to note that not all women taking trazodone will experience these side effects. Some women may experience different side effects not listed here. It is also possible for some Trazodone female side effects to improve over time or with a dosage adjustment. If you are taking trazodone and experience any concerning side effects, you must notify your healthcare provider.
Other Trazodone Side Effects
In addition to the side effects mentioned above, trazodone may cause other side effects not listed here, which may vary from person to person. It’s necessary to know how the medication affects you personally and communicate any concerns or changes to a healthcare provider.
Trazodone is not suitable for everyone, and people with certain medical conditions or taking specific medications should avoid using it unless advised otherwise by a healthcare provider. It’s also necessary to note that trazodone should not be stopped abruptly, as this may cause withdrawal symptoms, including nausea, headache, fatigue, and irritability. It’s vital to consult a healthcare provider about tapering off trazodone if it is no longer needed.
Trazodone Side Effects Precautions
It’s essential to use caution when using trazodone, especially when driving or operating heavy machinery, as trazodone may cause drowsiness and impair reaction time.
In conclusion, while trazodone is an effective medication for certain conditions, it’s essential to be aware of its possible side effects. Patients must follow the recommended dosage and discuss adverse effects with their healthcare provider. Also, patients with existing medical conditions should discuss the use of trazodone with their healthcare provider to prevent potential complications.
Serious Trazodone Side Effects
Less frequent but severe Trazodone side effects may include suicidal ideas, behavior-serotonin syndrome, allergic response, lower blood pressure, Mania or hypomania, erratic heartbeat, chest pains, shortness of breath, swelling in the extremities, sight changes, seizures, lengthy and aching erections.
How to Minimize Trazodone Side Effects?
To avoid and minimize Trazodone side effects, it’s essential to use trazodone safely in accordance with the recommended dosage and duration. It is vital to use it as directed by a healthcare provider. Taking medications for a longer period or exceeding the recommended dose may cause adverse health effects, including possible overdose.
It’s also necessary to avoid taking trazodone with other medications, supplements, or substances that may interact with it unless advised otherwise by a healthcare provider.
Report Trazodone Side Effects
While trazodone is useful in treating certain conditions, taking it only as prescribed by a healthcare provider, reporting any side effects immediately, and taking necessary precautions to ensure safe and effective use is vital.
For example, trazodone can cause a sudden drop in blood pressure, leading to light-headedness, dizziness, and even fainting. Patients with underlying heart or blood pressure problems may be more susceptible to these adverse effects. Trazodone can also trigger serotonin syndrome, a rare but potentially life-threatening condition characterized by confusion, agitation, rapid heartbeat, shivering, sweating, and high fever.
Another serious side effect of trazodone use is the potential for suicidal thoughts or behavior. Studies suggest that patients taking trazodone have a higher risk of suicide than those not taking antidepressant medication. Finally, trazodone may cause prolonged and painful erections (priapism). This condition can be severe and requires immediate medical attention, as it may result in permanent damage to the penis.
Trazodone Sexual Side Effects
Trazodone is known to have some potential sexual side effects. Trazodone sexual side effects may sometimes decrease sex drive and cause difficulty reaching orgasm or erectile dysfunction in males. In females, trazodone may also cause decreased sex drive and difficulty achieving orgasm. Some people may also experience Trazodone sexual side effects, with changes in sexual desire, or experience sexual dysfunction due to using trazodone.
If you experience Trazodone sexual side effects while taking medicine, you must talk to your healthcare provider. They may be able to adjust your dosage or switch you to a different medication to address these concerns. It is also important to always take medications as prescribed and not stop taking trazodone or any other medication without consulting a healthcare provider.
What are Trazodone long term side effects?
Long-term use of trazodone may be associated with certain side effects. Some of these potential long-term side effects may include:
- Cognitive impairment or memory loss
- Tremors or muscle stiffness
- Increased risk of falls or fractures
- Risk of serotonin syndrome (a serious condition that can be life-threatening) when used in combination with other medications that affect serotonin levels
- Development or worsening of cardiac abnormalities, especially in patients with preexisting heart conditions
- Sleep-related issues, including disruptive or vivid dreams, sleepwalking, or sleep apnea
- Weight changes or metabolic disturbances.
It is vital to talk to your healthcare provider if you are experiencing any long-term effects or other concerning symptoms while taking trazodone. They can provide personalized advice and guidance based on your specific medical history and needs. Additionally, it is important to attend regular follow-up appointments with your healthcare provider to monitor and manage any potential long-term effects.
Trazodone and Alcohol Fact Sheet
Alcohol can increase the nervous system side effects of trazodone such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. You should avoid or limit the use of alcohol while being treated with trazodone.
It’s best to avoid combining antidepressants and alcohol. It may worsen your symptoms, and it can be dangerous. If you mix antidepressants and alcohol:
- You may feel more depressed or anxious. Drinking can counteract the benefits of your antidepressant medication, making your symptoms more difficult to treat. Alcohol may seem to improve your mood in the short term, but its overall effect increases symptoms of depression and anxiety.
- Side effects may be worse if you also take another medication. Many medications can cause problems with alcohol, including anti-anxiety, sleep, and prescription pain medications. Side effects may worsen if you drink alcohol and take one of these drugs with an antidepressant.
- Your thinking and alertness may be impaired. The combination of antidepressants and alcohol will affect your judgment, coordination, motor skills, and reaction time more than alcohol alone. Some combinations may make you sleepy. This can impair your ability to drive or do other tasks that require focus and attention.
- You may become sedated or feel drowsy. A few antidepressants cause sedation and drowsiness, and so does alcohol. When taken together, the combined effect can be intensified.
What is Trazodone Used for?
Trazodone is an antidepressant that inhibits serotonin type 2 receptors and serotonin transporter. It is a triazolopyridine derivative. Trazodone inhibits the reuptake of serotonin and blocks the histamine and alpha-1-adrenergic receptors. It also induces significant changes in 5-HT presynaptic receptor adrenoreceptors. The Trazodone category is of SARI drugs (serotonin antagonists and reuptake inhibitors), with other members being etoperidone, phenylpiperazine, lorpiprazole, and mepiprazole.
Trazodone administration is via the oral route. It may be taken after meals to decrease postural hypotension and lightheadedness. Trazodone may be available as immediate-release (IR) tablets, prolonged-release tablets, and in some cases, injection and oral drops solutions. It can take one to two weeks before trazodone starts to work, but maybe four to six weeks before you feel the full benefit.
Can you take Trazodone for anxiety attack? Trazodone can also include treatment for the effects of alcohol withdrawal, anxiety treatment, medications for schizophrenia treatment, and uncontrolled movements resulting from side effects from other medications. Trazodone for pain is also frequent off-label use of drugs, and in particular, it can be helpful for chronic pain conditions like fibromyalgia. Individuals with chronic pain are often given antidepressants and medications that control the pain. This is because of chronic pain’s effects on mood and the likelihood of developing depression.
Trazodone should not be used in patients with a history of heart disease or a recent heart attack. This medication can cause or worsen QT prolongation (a disorder of the heart), which can cause an irregular heart rhythm that can lead to seizures, fainting, or even death.
Is Trazodone a Narcotic?
Trazodone is not a narcotic. Narcotics are opioids—drugs that relieve pain by blocking the pain receptors in your brain. Trazodone is an antidepressant medication that alters brain chemicals called neurotransmitters to help ease depression.
Trazodone is it a Controlled Substance?
While trazodone is not a narcotic or a controlled substance, specific research on the abuse potential of trazodone is lacking. Clinical trials of trazodone did not show any signs of drug-seeking behavior. Trazodone is intended for use in people with depression. However, trazodone is often prescribed off-label for other conditions, such as insomnia, and the drug’s abuse potential has not been studied for these uses.
Trazodone for Sleep Disorder
Trazodone is not classified by the FDA as a controlled substance, unlike medications such as Lunesta and Ambien. This means that Trazodone is not considered to have potential abuse and misuse. Because trazodone is not classified as a controlled substance, doctors do not have strict limits on how many pills they’re able to prescribe.
Trazodone for sleep disorder treatment medication has the advantage of being an effective treatment for insomnia. Trazodone is helpful at low doses for primary and secondary insomnia. Moreover, it is less expensive than some newer insomnia medications due to its availability. At low doses, trazodone as a sleep aid is often very effective for insomnia.
Post-traumatic stress disorder, a psychiatric disorder, arises following exposure to perceived life-threatening trauma. Its symptoms can mimic those of anxiety or depressive disorders. Current treatment strategies combine patient education and pharmacologic interventions, such as selective serotonin reuptake inhibitors, trazodone and clonidine, and psychotherapy.
Trazodone (Desyrel) at 50 to 200 mg has SSRI properties and serotonin blockade action. It reverses SSRI-induced insomnia; augments the antidepressant effects of SSRIs; promotes sleep through its sedative properties, and suppresses rapid eye movement sleep, thus reducing the nightmares associated with PTSD.
FDA Guidelines for Proper Dose of Trazodone
Before prescribing Trazodone, your doctor will ask you if you have any allergies and what other medications you are taking. This ensures that the Trazodone will not cause an allergic reaction or interact with the other drugs. You must mention if you or they have heart, kidney, or liver disease, blood pressure problems, or a history of glaucoma or substance abuse.
Trazodone can cause dizziness, drowsiness, and blurred vision; your doctor will advise you not to drive or use machinery until these symptoms pass. If you smoke marijuana, you should tell your doctor. Can you drink on trazodone? Smoking marijuana or drinking alcohol can increase dizziness sometimes experienced when taking Trazodone.
According to the Food and Drug Administration (FDA), dosing should be as follows:
- For the treatment of depression, a usual starting dose is 150 milligrams (mg) per day. When the regular tablets are taken, this would most likely be scheduled as 75 mg in the morning and 75 mg at night.
- For the treatment of insomnia, the dose is usually started at 25 to 50 mg at night.
Your healthcare provider will then work with you to find the correct dose and may increase your dose every few days. Check your prescription and talk to your healthcare provider to ensure you take the correct dose.
Trazodone 50 mg Side Effects
One of the most common side effects associated with trazodone 50 mg is drowsiness. Other side effects may include dry mouth, increased appetite, constipation, or difficulty sleeping. Some people may experience headache, dizziness, confusion, nausea or vomiting, blurred vision, and weight gain when taking trazodone 50 mg. Rarely reported but more serious side effects include changes in heart rate and/or rhythm and muscle twitching. If any of these symptoms persist or worsen after starting trazodone 50 mg it is important to seek medical advice immediately.
In addition to physical side effects associated with trazodone 50 mg use, some mental health side effects have been reported as well. These can include anxiety, agitation, and mood swings. It is also possible to see an increase in suicidal thoughts or behavior when taking trazodone 50 mg. If any of these mental health side effects occur while taking trazodone 50 mg, contact a healthcare professional right away.
It is important to note that trazodone 50 mg may interact with other medications or substances and can cause unexpected dangerous side effects. Make sure you speak with your doctor before taking trazodone 50 mg if you are currently on any other medications or supplements, as well as if you have any existing medical conditions or allergies. Taking trazodone 50 mg without first consulting a healthcare provider can be risky and should be avoided.
If you experience any side effects while taking trazodone 50 mg, contact your doctor right away. Do not stop or change the dosage of trazodone 50 mg without consulting your healthcare provider first. Doing so can cause serious harm and should always be done with medical supervision.
Overall, trazodone 50 mg is a medication that carries risks along with potential benefits. Knowing and understanding the side effects associated with trazodone 50 mg is essential in order to safely use this drug and enjoy its full benefits. Always consult a qualified medical professional before taking trazodone 50 mg for proper diagnosis and treatment of any condition you may have.
Trazodone Long Term Side Effects
What are Tazodone long term side effects? Trazodone is a widely prescribed antidepressant, but there may be long-term side effects associated with its use. In some cases, trazodone long term side effects can cause physical and mental health problems that last long after the patient has stopped taking the medication.
Common Trazodone long term side effects include changes to cardiovascular health such as high blood pressure, an increased risk of heart attack or stroke, and an irregular heartbeat. It can also increase cholesterol levels and worsen existing diabetes.
Other trazodone side effects long term are difficulty breathing, confusion, impaired concentration and memory loss. Psychiatric symptoms like depression or anxiety could be exacerbated by prolonged use of trazodone. If you have been taking trazodone for a prolonged period of time, it is wise to talk to your doctor about the long term side effects of trazodone. Your doctor can help you manage and monitor any potential adverse effects associated with its use.
It is also important to remember that trazodone should only be used as prescribed by your doctor. With caution and proper management, trazodone may be an effective treatment option for many patients who suffer from depression or other mental health conditions.
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Is Trazadone Addictive?
Trazodone is addictive or habit-forming, but not in the same way that drugs like cocaine, meth, or heroin are. Rather than an all-consuming physical addiction, a person who abuses trazodone may develop a physical dependence on it and a psychological addiction to it.
Dependence on this drug is marked by withdrawal symptoms of Trazodone when the person reduces their dosage or ceases use completely. Alongside dependence, a person may also develop a psychological addiction to trazodone, in which they might feel they have to use it to feel normal or be happy.
Does Trazodone Get You High?
Although trazodone cannot get you high in the same way drugs as opioids or stimulants can, it can have sedative effects. Despite the lack of euphoria in a trazodone high, the medication produces a relaxing and calming effect that users might find desirable. Trazodone abuse can occur in people to whom it’s been prescribed and in people who take it for trazodone recreational purposes.
Trazodone Side Effects Overview
Trazodone may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
- Changes in appetite or weight
- Weakness or tiredness
- Dizziness or lightheadedness
- Muscle pain
- Dry mouth
- Sexual problems in males; decreased sex drive, inability to get or keep an erection, or delayed or absent ejaculation.
- Sexual problems in females; decreased sex drive, delayed orgasm, or inability to orgasm.
- Uncontrollable shaking of a part of the body
- Stuffy nose
- Tired, red, or itchy eyes
Some side effects can be severe. If you experience any of the following symptoms, call your doctor immediately or get emergency medical treatment:
- Chest pain
- Fast, pounding, or irregular heartbeat
- Loss of consciousness (coma)
- Fever, sweating, confusion, fast or irregular heartbeat, severe muscle stiffness or twitching, agitation, hallucinations, loss of coordination, nausea, vomiting, or diarrhea
- Shortness of breath
- Unusual bruising or bleeding
- Small red or purple dots on the skin
- Erection lasting more than 6 hours
- Problems with thinking, concentration, or memory
- Problems with coordination
What are the Long-Term Side Effects of Trazodone?
While trazodone is generally safe and effective when used as prescribed for its intended purpose, an individual who abuses trazodone for extended periods may be at risk of experiencing more intense side effects, long term effects trazodone may include:
- Decreased serum sodium levels (hyponatremia) and associated symptoms (headache, concentration problems, memory problems, confusion, weakness, instability, increased fall risk)
- Serotonin syndrome
- Angle-closure glaucoma
- Blurred vision
- Coordination problems
- Gastrointestinal upset
- Heart rate and rhythm abnormalities
Trazodone Off Label Uses
Other, not officially approved (off-label) uses of trazodone include the treatment of bulimia, benzodiazepine, and alcohol dependence or abuse, fibromyalgia, degenerative diseases of the central nervous system such as dementia and other organic disorders, schizophrenia, chronic pain, and diabetic neuropathy . Few clinical trials have been conducted to evaluate trazodone’s efficacy in treating the diseases and symptoms for which it is often used in clinical practice. More studies are necessary to investigate possible new therapeutic indications and to scientifically demonstrate the risk/benefit ratio for the many conditions for which trazodone is used but not approved by the FDA.
Trazodone Side Effects Hallucinations
Can trazodone cause hallucinations? According to the National Center for Biotechnology Information , there was a case of a 60-year-old man who received trazodone for primary insomnia. Two days later, he returned to the emergency department with distressing visual hallucinations, which prompted inpatient treatment. Trazodone was discontinued, leading to a complete resolution of his visual hallucinations.
Hallucinations are sensory perceptions that occur without an external stimulus in any sensory modality. Visual Hallucinations are more common in acute organic states with clouding of consciousness and patients with neurodegenerative disorders. We report a case of trazodone-induced visual hallucinations that, to our knowledge, is the first described in the literature.
While a trazodone high isn’t a reported effect with this drug, however, if you mix it with other substances, it can amplify the effects of those. For example, if you combine trazodone and alcohol, it can increase your responsiveness to the alcohol. This can occur with any type of central nervous system depressant, so it’s important to let your doctor know of any other substances you use before taking trazodone.
Taking MAO inhibitors with this medication may cause a serious (possibly fatal) drug interaction. Avoid taking MAO inhibitors (isocarboxazid, linezolid, metaxalone, methylene blue, moclobemide, phenelzine, procarbazine, rasagiline, safinamide, selegiline, tranylcypromine) during treatment with this medication. Most MAO inhibitors should also not be taken for two weeks before and after treatment with this medication.
Can Trazodone Cause Serotonin Syndrome?
Trazodone may cause a serious condition called serotonin syndrome if taken with some medicines. Do not use trazodone with buspirone, fentanyl, lithium, tryptophan, St. John’s wort, or some pain or migraine medicines. Serotonin syndrome is a rare but potentially life-threatening adverse drug reaction resulting from the use or overuse of serotonergic medications alone or in combination. The major reasons for an often missed diagnosis are mild symptoms, overlapping features with similar conditions, and clinician lack of awareness. Serotonin syndrome is potentially deadly .
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The serotonin syndrome/toxicity risk increases if you also take other drugs that increase serotonin. Examples include street drugs such as MDMA/”ecstasy,” certain antidepressants (including SSRIs such as fluoxetine (Prozac), and SNRIs such as duloxetine/venlafaxine), among others. The serotonin syndrome/toxicity risk may be more likely when you start or increase the dose of these drugs.
Clinical symptoms of serotonin syndrome can develop within two hours—or up to 24 hours—after taking an increased dose or adding another serotonergic drug.
Signs and symptoms of serotonin syndrome:
- Muscle aches
- Renal failure
Trazodone and Alcohol
Can you drink with Trazodone? Drinking alcohol while taking trazodone can be dangerous. Trazodone may amplify some of the effects of alcohol, which can lead to dangerous levels of intoxication and even overdose and trazodone and alcohol death. The combination can also cause extreme drowsiness, leading to accidents and injuries. In addition, alcohol can increase the risk of depression, anxiety, and other mental health problems such as anxiety disorders, depression, and suicidal thoughts. Some users who have mixed trazodone with alcohol claim the combination impairs their thinking and judgment. Alcohol is a depressant, and combining an antidepressant with a depressant can lead to unpredictable and dangerous consequences for different users.
Trazodone Interactions with Alcohol
What are the signs of trazodone and alcohol interactions? Trazodone has a possibility for physical dependence when consumed with alcohol. Drinking 50mg of trazodone and alcohol is no exception. Furthermore, this deadly combination can lead to delirium, hallucinations, and seizures in extreme cases. Trazodone alcohol interaction can lead to severe side effects that affect a person’s overall health.
As mentioned, trazodone 50 mg and alcohol can amplify each other’s effects. Since both agents are central nervous system depressants, taking them together can be risky due to additive side effects from their drug interactions, which include:
- Difficulty concentrating
- Impairment in thinking and judgment
- Dramatic mood swings
- Increased depression or anxiety
- Increased intoxication
Trazodone and Alcohol Withdrawal
Long-term use of alcohol and trazodone can also lead to the development of physical dependence and withdrawal symptoms. Trazodone alcohol withdrawal symptoms can include agitation, anxiety, and sleep problems. Instead of coming off Trazodone cold turkey, people on the medication are advised to be tapered or gradually weaned off under the care of a physician.
Severe alcohol withdrawal syndrome can be pretty serious. It can include symptoms such as alcohol-induced insomnia, increased body temperature, anxiety, rapid pulse, sweating, nausea, and vomiting, as well as more severe complications such as hallucinations or alcohol-induced psychosis, agitation, delirium, and seizures. Left unmanaged, alcohol withdrawal can even be life-threatening due to the possibility of grand mal seizures.
Individuals who have become dependent on alcohol and Trazodone may need medically-supervised withdrawal management and detox—either as part of a standalone program or at the start of a rehabilitation program. Medical-supervised detox programs are staffed with healthcare professionals who can monitor the individual’s recovery during withdrawal and provide therapeutic interventions when needed.
What are trazodone withdrawal side effects? Trazodone withdrawal is the body’s process of readjusting to the absence of a drug in its system. For example, after a consistent amount of time taking the drug, the brain and body become used to trazodone and adapt to its presence. Can you have withdrawals from trazodone? If you suddenly quit taking trazodone, you may feel ill as your body readjusts after the change in routine. Trazodone withdrawal can be very challenging for people attempting to stop trazodone.
Attempting to manage the withdrawal symptoms of Trazodone without medical supervision can be dangerous. This is especially true if you take trazodone to treat mood issues like depression, which may worsen if you suddenly quit the drug.
Withdrawal Symptoms from Trazodone
When an individual is going through Trazodone withdrawal symptoms, discomfort is common. Other physical symptoms associated with trazodone withdrawals include:
- Trouble sleeping
- Irritabilitytrazodone withdrawal
Since trazodone is often prescribed to treat mental health issues like depression, there are adverse effects when abruptly stopping use. Individuals who struggle with depression and take trazodone for treatment may feel increased depression during Trazodone withdrawal. For this reason, it is important only to stop taking trazodone under a doctor’s care.
How Long Does Trazodone Withdrawal Last? Trazodone Withdrawal Timeline
Everyone experiences trazodone withdrawal symptoms differently. For some individuals, physical symptoms could subside in just a few days. For others, they could last weeks or longer. When individuals experience withdrawal from antidepressant medications such as trazodone, various factors influence the duration of trazodone withdrawal and the intensity of symptoms. These include:
- How long has the individual been taking trazodone
- Dosage amount before starting trazodone withdrawal
- Individual characteristics
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Popular Side Effects of Trazodone FAQs
What are Trazodone 50 mg side effects?
Trazodone 50 mg side effects are the same as other dosings. Trazodone is an antidepressant medication that is often prescribed in 50mg doses. Some of the common side effects associated with trazodone 50 mg may include lightheadedness, tiredness, dry mouth, vision issues, headaches, vomiting, stomach aches, constipation, diarrhea, feeling weakness, muscle aches, changes in appetite or weight, nervousness, anxiety, or agitation.
Side effects of trazodone 50 mg are the same as at other dose amounts.
What are Trazodone side effects in elderly?
Trazodone side effects in elderly as the same as other dosing amounts. As with any medication, there are potential side effects associated with trazodone use in elderly patients. Common side effects of trazodone in elderly patients may include all of Trazodone side effects.
However, in elderly patients, there is also an increased risk of falls due to the potential for dizziness, lightheadedness, or fatigue associated with trazodone use. Additionally, trazodone may cause changes in heart rate, blood pressure, or electrolyte imbalances, which could potentially impact elderly patients more severely.
Do Trazodone side effects go away?
In some cases, Trazodone side effects may go away on their own as the body adjusts to the medication. However, this may not always be the case for everyone. Some Trazodone side effects may persist or even worsen over time.
What are Trazodone side effects weight gain?
Trazodone is not commonly associated with significant weight gain as a side effect. However, some people may experience changes in appetite or weight while taking trazodone. These changes may manifest as weight loss or weight gain, although weight gain is less common.
The mechanism by which trazodone may impact weight gain is not well understood. Some researchers suggest that trazodone may affect the balance of hormones that regulate appetite and weight, leading to changes in eating habits and body composition. Others suggest that trazodone may have a sedative effect, which may lead to decreased physical activity or exercise.
If you experience concerns about Trazodone side effects weight gain changes while taking the mediation, it is vital to talk to your healthcare provider. They can provide personalized advice and guidance based on your specific medical history and needs.
What are trazodone male side effects?
Trazodone is an antidepressant medication that can have some potential side effects in males. Some of the common trazodone male side effects may include:
Trazodone erectile side effects (difficulty achieving or maintaining an erection)
Priapism (painful, prolonged erection)
Decreased libido or sex drive
Delayed ejaculation or difficulty reaching orgasm
Blurred vision or dizziness
It is important to note that not all males who take trazodone will experience these side effects, and some people may experience different or no side effects at all. It is also possible for some of these side effects to improve over time or with a dosage adjustment.
If you are experiencing any concerning side effects while taking trazodone, it is important to talk to your healthcare provider. They may be able to adjust your dosage or switch you to a different medication to address your concerns.
What are side effects of Trazodone for sleep?
Trazodone is a medication commonly used to treat sleep disorders, such as insomnia. Some of the common trazodone side effects for sleep may include drowsiness or feeling tired during the day as well as dizziness or lightheadedness.
It is important to note that not all people who take trazodone for sleep will experience these side effects, and some people may experience different or no side effects at all.
While trazodone is commonly used to help people sleep, it is important to follow your doctor’s dosing instructions closely and not to take more than prescribed. Taking too much trazodone can increase the risk of side effects and can be dangerous.
If you are experiencing any concerning side effects while taking trazodone for sleep, it is important to talk to your healthcare provider. They can provide personalized advice and guidance based on your specific medical history and needs.
What are Trazodone cardiac side effects?
Although rare, trazodone use has been associated with some potential cardiac side effects. Some of these potential cardiac side effects of trazodone may include:
Abnormal heart rhythms, including QT prolongation
Electrolyte imbalances, which can lead to heart arrhythmias
Hypotension (low blood pressure), which can cause dizziness or fainting
Myocardial infarction or stroke in patients with pre-existing heart disease
It is essential to understand these side effects are relatively rare and are more commonly seen in patients with pre-existing cardiac conditions or in patients taking other medications that can affect the heart.
If you have any pre-existing cardiac conditions or are taking other medications that can affect the heart, it is important to talk to your healthcare provider before starting trazodone. Additionally, it is important to watch for any signs of cardiac side effects and to report any concerning symptoms to your healthcare provider as soon as possible.
What is the side effects from stopping trazodone?
It is important to never stop taking trazodone or any other medication suddenly without consulting with your healthcare provider. Stopping trazodone abruptly can cause withdrawal symptoms, which may include:
Insomnia or difficulty sleeping
Anxiety or restlessness
Irritability or agitation
Dizziness or lightheadedness
Nausea or vomiting
Sweating or tremors
Fatigue or lethargy
Electric shock sensations
The severity and duration of these withdrawal symptoms may vary based on factors such as the dose of trazodone, the duration of use, and individual patient characteristics. In general, it is recommended to gradually taper off trazodone under the guidance of a healthcare provider to minimize the risk of withdrawal symptoms.
What are Trazodone side effects weight loss symptoms?
Trazodone is generally not associated with significant weight loss as a side effect. However, some people may experience changes in appetite or weight while taking trazodone, and in rare cases, weight loss may occur.
The way by which trazodone may impact weight loss is not well understood, but it is suggested that trazodone may affect the balance of hormones that regulate appetite and weight.
If you experience concerns about weight changes while taking trazodone or any other side effects, it is important to talk to your healthcare provider. They can provide personalized advice and guidance based on your specific medical history and needs. It is also important to attend regular follow-up appointments with your healthcare provider to monitor any potential side effects.
Trazodone Sexual Side Effects Overview
Trazodone is known to have some potential sexual side effects. In some cases, trazodone may decrease sex drive and cause difficulty reaching orgasm or erectile dysfunction in males. In females, trazodone may also cause decreased sex drive and difficulty achieving orgasm. Some people may also experience changes in sexual desire or experience sexual dysfunction as a result of using trazodone.
Common Trazodone side effects sexually related with taking drug may include:
- Decreased sexual desire or drive
- Difficulty achieving orgasm
- Delayed ejaculation or anorgasmia (inability to reach orgasm)
- Erectile dysfunction
- Priapism (an erection that does not go away)
- Painful or uncomfortable sexual experiences
It is important to note that not everyone who takes Trazodone will experience these Trazodone sexual side effects, and some people may experience different or no side effects at all. It is also possible for some Trazodone’s side effects sexually affecting performance to improve over time or with a dosage adjustment.
If you are experiencing any concerning Trazodone sexual side effects, it is important to talk to your healthcare provider. They may be able to adjust your dosage or switch you to a different medication to address these concerns.
It is important to always take medications as prescribed and not to stop taking trazodone or any other medication without consulting with a healthcare provider.
What are Trazodone Male Side Effects?
Trazodone is an antidepressant medication that can have some potential side effects in males. Some of the common trazodone male side effects may include mutliple stymptoms.
Affects of Trazodone Side Effects Sexually Male include the following:
- Trazodone erectile side effects (erectile dysfunction difficulty achieving or maintaining an erection in males)
- Priapism (painful, prolonged erection)
- Decreased libido or sex drive
- Delayed ejaculation or difficulty reaching orgasm
Other Trazodone males side effects include:
- Blurred vision or dizziness
Typical Trazodone side effects in males may not apply to all males. Some males may experience different or no side effects at all. It is also possible for some of these side effects to improve over time or with a dosage adjustment.
If you are experiencing any concerning side effects while taking trazodone, it is important to talk to your healthcare provider. They may be able to adjust your dosage or switch you to a different medication to address your concerns.
Treatment for Trazodone Side Effects and Alcohol Abuse
To determine the most effective ways to treat Trazodone side effects and co-occurring alcohol addiction, it’s crucial to assess all the symptoms accurately. When a mental health professional has evaluated the symptoms, it may be determined that another form of depression is present and needs a particular treatment. Very often, some combination of medication, psychotherapy, and lifestyle changes are effective for coping with functional.
Detox is often considered the first stage of treatment. It will help you navigate the complicated process of alcohol withdrawal but doesn’t address patterns of thought and behavior that contribute to alcohol use. Various treatment approaches and settings can help provide the ongoing support necessary to maintain long-term sobriety after you complete detox.
Cravings are pervasive side effects of Trazodone during detox and can be challenging to overcome. This often leads to relapse. Constant medical care provided during inpatient treatment helps prevent relapse. Clinicians can give the necessary medication and medical expertise to lessen cravings and the effects of alcohol withdrawals.
Psychotherapy for Depression
Several different modalities of psychotherapy have been used in the treatment of depression, including:
- Cognitive Behavioral Therapy (CBT) – is an effective treatment that involves changing both the patterns of negative thoughts and the behavioral routines which are affecting the daily life of the depressed person for various forms of depression.
- Person–centered therapy is a strategy that allows and encourages clients to understand and resolve their concerns in a safe, supportive environment.
- Solution Focused Therapy – an approach interested in solutions that can be quickly implemented with a simple first step leading to further positive consequences.
Dual Diagnosis Treatment
Alcoholism and mental health disorders often co-occur. In many cases, traumatic experiences can result in mental health disorders and substance abuse. Dual diagnosis rehabilitation treats both of these issues together. The best approach for the treatment of dual diagnosis is an integrated system. This strategy treats both the substance abuse problem and the mental disorder simultaneously. Regardless of which diagnosis (mental health or substance abuse problem) came first, long-term recovery will depend largely on the treatment for both disorders done by the same team or provider.
Medication-Assisted Treatments (MAT) for alcohol use and mental health disorders are commonly used in conjunction with one another. This includes the use of medications and other medical procedures. During your rehab, the staff from your treatment facility will help you identify what caused your addiction and teach you skills that will help you change your behavior patterns and challenge the negative thoughts that led to your addiction. Sometimes, the pressures and problems in your life lead you to rely on substances to help you forget about them momentarily.
Contact one of our helpful treatment specialists today if you or a loved one are struggling with long-term substance abuse, Trazodone side effects, and other co-occurring mental health conditions such as depression. We Level Up NJ can provide information on dual diagnosis and detox programs.
Top 5 Most Trazodone and Alcohol Frequently Asked Questions
Can you mix trazodone and alcohol?
Drinking alcohol while taking trazodone can be dangerous. Trazodone may amplify some of the effects of alcohol, which can lead to dangerous levels of intoxication and even overdose and death. The combination can also cause extreme drowsiness, leading to accidents and falls.
What are the risks of combining trazodone Xanax and alcohol?
You can theoretically take Xanax and trazodone together, but you might experience heightened side effects of one or both. For example, you might experience confusion, dizziness, and coordination and concentration problems if you take Xanax and trazodone together. These side effects of the two drugs combined can be worst with alcohol.
Is it safe mixing trazodone and alcohol?
No. The combination of trazodone and alcohol will affect your judgment, coordination, motor skills, and reaction time more than alcohol alone. Some combinations may make you sleepy. This can impair your ability to drive or do other tasks that require focus and attention. You may become sedated or feel drowsy.
How does trazodone help with alcohol dependence?
Trazodone, a second-generation antidepressant, is helpful in the treatment of lasting alcohol withdrawal symptoms, such as sleep disturbances and cravings. But mixing them is not advisable and can only lead to adverse effects.
Can I take trazodone 2 hours after drinking?
When taking antidepressants, you should not drink alcohol at all. Trazodone may amplify some of the effects of alcohol, which can lead to dangerous levels of intoxication and even overdose and death.
List of Popular Trazodone Side Effects FAQs
Is trazodone an opiate?
No. Trazodone is in a class of medications called serotonin modulators. It works by increasing the amount of serotonin, a natural substance in the brain that helps maintain mental balance.
Can you take trazodone after drinking?
Drinking alcohol with trazodone is not recommended. What happens if you take trazodone with alcohol? For one, it can worsen trazodone’s side effects, such as drowsiness or blurred vision.
Can you drink alcohol with trazodone?
Can you take trazodone with alcohol? Drinking alcohol while taking trazodone can be dangerous. Trazodone may amplify some of the effects of alcohol, which can lead to dangerous levels of intoxication and even overdose and death. Drinking on trazodone can be risky.
Can you get high off trazodone?
Although trazodone cannot get you high in the same way drugs as opioids or stimulants can, it can have sedative effects.
Is Trazodone and Xanax the same thing?
No. You might experience the same side effects while taking Xanax or trazodone, but the two drugs belong to different medication classes. Trazodone is a selective serotonin reuptake inhibitor (SSRI), while Xanax is a benzodiazepine.
Can trazodone cause seizures?
Epileptic seizures were reported because of high-dose trazodone use. The abuse of trazodone and seizures are interconnected.
How to get off trazodone?
Tapering use or detoxing from trazodone under medical supervision can help ease you off the drug and minimize withdrawal symptoms.
How many trazodone can you take for sleep?
When prescribed for sleep, trazodone can be taken in several doses: The starting dose is usually 50 mg to 100 mg at bedtime. If needed, the dose can be increased to 200 mg at bedtime. Please consult your doctor.
Can you abuse Trazadone?
Sadly, the recreational use of trazodone is on the rise. Although it doesn’t cause euphoria, the drug produces a relaxing, calming effect that users find desirable. Recreationally, trazodone is called by the street name “sleepeasy.”
Can you take trazodone with Wellbutrin?
Combining trazodone and Wellbutrin may increase the risk of seizures, which may rarely occur with either medication.
How long does trazodone last in your system?
Trazodone’s half-life is 5–9 hours, meaning it will take about 25–45 hours for trazodone to be out of the system.
Does trazadone cause dry mouth?
Trazodone may cause dry mouth. Use sugarless gum or candy, melt bits of ice in your mouth, or use a saliva substitute for temporary relief.
Can you take Zoloft and trazodone together?
Using Trazodone together with Zoloft can increase the risk of a rare but serious condition called serotonin syndrome, which may include symptoms such as confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking.
Can you take trazodone with oxycodone?
Using trazodone and oxycodone can increase the risk of a rare but serious condition called serotonin syndrome, which may include symptoms such as confusion, hallucinations, seizures, extreme changes in blood pressure, and increased heart rate. Taking oxycodone and trazodone for recreational purposes is risky.
Do trazodone side effects go away?
Some Trazodone common side effects may go away during treatment as the body adjust to the medicine.
How to get trazodone out of your system fast?
After a single dose in a healthy adult, trazodone will be mostly out of your system in one to three days. For trazodone the half-life is approximately 5 to 13 hours.
Is Trazodone addictive?
Trazodone is addictive or habit-forming, but not in the same way that drugs like cocaine, meth, or heroin are.
What are trazodone benefits?
This medication is used to treat depression. It may help to improve your mood, appetite, and energy level and decrease anxiety and insomnia related to depression.
What are the long term side effects of trazodone?
Regarding trazodone long term effects, it’s considered a relatively safe substance. There aren’t currently believed to be any serious trazodone long-term effects on the brain from repeated use, which is one of the reasons it is preferred over other antidepressants and sleep aids in some cases.
What are the side effects of trazodone 150 mg?
Like all medicines, trazodone can cause side effects, although not everybody gets them.
Talk to your doctor straight away if you notice the following side-effects:
- You have thoughts of harming or killing yourself
- Feeling tired, faint, dizzy, and having pale skin. These could be signs of anemia
Can you take Percocet and trazodone together?
Using Percocet and trazodone together can increase the risk of a rare but serious condition called serotonin syndrome, which may include symptoms such as confusion, hallucinations, seizures, extreme changes in blood pressure, increased heart
What are the side effects stopping trazodone?
Trazodone withdrawal side effects may include agitation or irritability, sleep disturbances or insomnia, anxiety, depression, mood swings, sweating, nausea, or digestive upset.
What are the effects of stopping trazodone cold turkey?
If you’ve become dependent on trazodone, speak to your doctor before stopping Trazodone cold turkey. Side effects of stopping trazodone cold turkey after a period of dependence may cause more intense and uncomfortable withdrawal symptoms.
What is trazodone side effects muscle pain?
Muscle aches and pains are a well-recognized possible side-effect of Trazodone. An irregular heartbeat is also a possible side effect.
What are the most common side effects of trazodone?
Summary Commonly reported side effects of trazodone include: blurred vision, dizziness, drowsiness, headache, nausea, vomiting, and xerostomia. Other side effects include: syncope, edema, ataxia, confusion, diarrhea, hypotension, insomnia, sedated state, and tachycardia.
What are the effects of the interactions of trazodone and wine?
The use of alcohol with trazodone will increase the effects of the medication making you more dizzy and drowsy. Drinking wine while on this medication or any other medication is not recommended.
Is Trazodone a benzo?
No. You might experience some of the same side effects while taking a bezo or trazodone, but the two medications belong to different medication classes.
What are Xanax and trazodone high?
Since both Xanax and trazodone have the potential for abuse, addiction, and dependence, the risk of these scenarios occurring may be higher if you take both together as well.
What are the psychological effects of trazodone?
Behavior or mood changes (eg, aggression, panic attacks) or. Bipolar disorder (mood disorder with mania and depression)
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Search We Level Up NJ Trazodone Side Effects Topics & Resources
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