Effects of Wellbutrin for Anxiety. Common Wellbutrin Dosage for Depression and Anxiety. What To Pair With Wellbutrin for Anxiety. Is Wellbutrin Good for Anxiety? Wellbutrin Dosage for Anxiety and Comprehensive Treatment Plans.

Is Wellbutrin for anxiety? Wellbutrin has been linked to anxiety in two ways – by alleviating anxiety and by causing it. Read on to find out more about the use of Wellbutrin, side effects, overdose, withdrawal symptoms and treatment.

Is Wellbutrin for Anxiety?

Wellbutrin (bupropion generic name) is an antidepressant medication used for major depressive disorder treatment (known as clinical depression or MDD) and seasonal affective disorder. Seasonal depressive disorder is episodes of depression that occur at the same time each year, usually in the fall and winter, but rarely may occur in the spring or summer months.

Does bupropion help with anxiety? Wellbutrin is primarily known as an antidepressant, but it’s also been effective in treating specific anxiety disorders. Its mechanism of action is different from other antidepressants, as it primarily affects the neurotransmitters norepinephrine and dopamine. This can make it a good option for individuals who experience both depression and anxiety.

Understanding the Wellbutrin side effects can help a patient better understand what to expect and ensure the person knows when they should contact their doctor or seek medical assistance.

What is Wellbutrin? Wellbutrin for Anxiety Guide

Wellbutrin is primarily prescribed as an antidepressant, but it is sometimes used off-label to address anxiety disorders. Its effectiveness in managing depression and anxiety can vary among individuals, and decisions regarding its use should be made in consultation with a healthcare provider.


What is Wellbutrin Used for?

Bupropion treats depression, aiming to enhance your mood and overall well-being. Its potential mechanism of action involves restoring a balanced state of specific natural chemicals (neurotransmitters) within your brain. Is Wellbutrin used for anxiety? Continue to read more about Wellbutrin uses for anxiety and how to take the medication properly.

When To Take Wellbutrin for Anxiety?

When To Take Wellbutrin?

Wellbutrin is typically taken once or twice daily, and the timing can vary depending on individual response and side effects. It’s advisable to follow your healthcare provider’s guidance, but many people find it in the morning effective to minimize potential sleep disturbances.

How To Use Wellbutrin for Anxiety 75 Mg Tablet?

How To Use Wellbutrin 75 Mg Tablet?

Administer this medication orally, with or without food, following your doctor’s guidance, typically three times daily. If you experience stomach discomfort, taking the drug with food is permissible. To reduce the likelihood of experiencing a seizure, it’s crucial to space your doses at least 6 hours apart, as instructed by your doctor.

The manufacturer advises against crushing, cutting, or chewing the tablet before consumption. Similar immediate-release tablets can be powdered, crushed, cut, or chewed. Abide by your doctor’s instructions on how to take this medication.

Adhere strictly to the prescribed dosage, neither increasing nor decreasing it, and avoid taking it more frequently than recommended. Overconsumption of bupropion beyond the prescribed dose may heighten the risk of seizure occurrence.

The prescribed dosage of this medication is contingent upon your medical condition and how you respond to the treatment. Your doctor may gradually increase your dose to minimize potential side effects, such as insomnia, and reduce the risk of seizures. To avoid sleep disturbances, refrain from taking this medication too late. If sleeplessness becomes problematic, communicate this with your doctor.

To maximize the benefits of this medication, use it consistently at the exact times each day. It is imperative to consult your doctor before discontinuing the medication, as some conditions may deteriorate when the drug is abruptly ceased. Your doctor may recommend a gradual reduction in dosage.

The complete therapeutic effects of this drug may take up to 4 or more weeks to become apparent. Continue adhering to your doctor’s instructions even after you start feeling better. Discuss your concerns with your doctor if your condition fails to improve or worsens.

Side Effects

Wellbutrin Anxiety Side Effects

While Wellbutrin can be beneficial for anxiety, it may initially exacerbate anxiety symptoms in some individuals. Common side effects of anxiety include restlessness, increased heart rate, and insomnia. If these side effects persist or worsen, it’s crucial to consult a healthcare professional for potential adjustments to the medication or alternative treatment options.

Wellbutrin for Anxiety Common Side Effects

Wellbutrin for Anxiety Common Side Effects

You might experience Wellbutrin symptoms, such as the following:

  • Nausea.
  • Vomiting.
  • Dry mouth.
  • Headaches.
  • Constipation.
  • Increased sweating.
  • Joint discomfort.
  • A sore throat.
  • Blurred vision.
  • An unusual taste in your mouth.
  • Diarrhea.
  • Dizziness while taking this medication.

If these effects persist or worsen, promptly inform your doctor or pharmacist.

Your doctor has prescribed this medication because they have determined that the benefits outweigh the potential side effects. Many individuals who use this medication do not encounter severe side effects.

This medication can elevate your blood pressure. It is advisable to regularly monitor your blood pressure and inform your doctor if you observe high readings.

Wellbutrin for Anxiety Severe Side Effects

Wellbutrin for Anxiety Severe Side Effects

Contact your doctor without delay if you experience any severe side effects, including the following:

  • Chest pain.
  • Fainting.
  • Rapid or irregular heartbeat.
  • Hearing difficulties.
  • Ringing in the ears.
  • Intense headaches.
  • Changes in mental state (such as agitation, anxiety, confusion, hallucinations, or memory loss).
  • Involuntary movements (tremors), unusual weight changes, muscle pain, tenderness, or weakness.

Seek immediate medical assistance if you encounter highly severe side effects, including eye pain, swelling, redness, dilated pupils, or alterations in vision like perceiving halos around lights during nighttime or if you experience a seizure.

Although exceedingly rare, a severe allergic reaction to this medication is possible. If you notice any signs of a severe allergic reaction, including a rash, itching, swelling (particularly of the face, tongue, or throat), severe dizziness, or difficulty breathing, promptly seek medical attention.


Wellbutrin Black Box Warning

Wellbutrin carries a black box warning due to the risk of increased suicidal thoughts, especially in children, adolescents, and young adults with major depressive disorder or other psychiatric disorders. Monitoring for any signs of worsening depression, suicidal thoughts, or unusual behavior is crucial when starting or adjusting the dosage of Wellbutrin. Individuals, caregivers, and healthcare providers must communicate closely and promptly address any concerns to ensure the safest medication use.

Wellbutrin for Anxiety Warnings

Wellbutrin Warnings

Before initiating bupropion, inform your doctor or pharmacist about any allergies related to bupropion or other substances. This product may include inactive ingredients that could trigger allergic reactions or other complications. For additional information, consult your pharmacist.

Before using this medication, provide your medical history to your doctor or pharmacist, especially if you have a history of seizures or factors that raise your seizure risk (such as head injuries, brain tumors, arteriovenous malformations, eating disorders like bulimia or anorexia nervosa), alcohol or drug dependency (including benzodiazepines, opioid pain medications, cocaine, and stimulants), diabetes, heart conditions (such as congestive heart failure, high blood pressure, or recent heart attacks), kidney disorders, liver issues (such as cirrhosis), a personal or family history of psychiatric disorders (like bipolar or manic-depressive disorder), an individual or family history of suicidal thoughts or attempts, or a personal or family history of glaucoma (particularly angle-closure type).

This medication should not be used if you are abruptly discontinuing regular usage of sedatives (including benzodiazepines like lorazepam), seizure medications, or alcohol, as this may heighten the risk of seizures.

This drug can induce dizziness or affect your coordination. The consumption of alcohol or marijuana (cannabis) can intensify dizziness and coordination impairment. Refrain from activities requiring alertness, such as driving or operating machinery, until you can do so safely. Avoid alcoholic beverages, which can also elevate the risk of seizures. If you are using marijuana (cannabis), discuss this with your doctor.

Older adults may be more vulnerable to the side effects of this medication, particularly dizziness and memory issues. Dizziness can increase the risk of falls in this age group.

While pregnant, this medication should only be used when it is unquestionably necessary. Since untreated mental or mood disorders (such as depression, seasonal affective disorder, and bipolar disorder) can be severe, refrain from discontinuing this medication unless explicitly instructed by your doctor. If you are contemplating pregnancy, become pregnant, or suspect you might be pregnant, promptly engage in a conversation with your doctor regarding the potential advantages and drawbacks of using this medication during pregnancy.

This drug can pass into breast milk, adversely affecting a nursing infant. It is advisable to consult your doctor before breastfeeding while using this medication.

Wellbutrin for Anxiety Risks

Wellbutrin Risks

Bupropion is an antidepressant for various conditions, including depression and various mental and mood disorders, aiding in smoking cessation. Antidepressants are crucial in averting suicidal thoughts or attempts and providing other substantial benefits. Nonetheless, research indicates that a small percentage of individuals, particularly those under 25, who use antidepressants for any purpose may encounter new or exacerbated depression, changes in mental and mood states, or even thoughts of suicide or suicide attempts. Therefore, it is imperative to discuss with your doctor the potential risks and advantages of antidepressant therapy, even when it’s not aimed at treating a mental or mood-related condition.

Notify your doctor promptly if you observe fresh instances of depression, new or worsening psychiatric conditions, unusual shifts in behavior (including potential suicidal thoughts or attempts), or other changes in mental and mood states (such as heightened anxiety, panic episodes, sleep disturbances, irritability, feelings of hostility or anger, impulsive actions, severe restlessness, or notably rapid speech). Pay close attention to these symptoms, particularly when initiating a new antidepressant or modifying the dosage.

For individuals using bupropion to quit smoking, discontinue the medication and contact your doctor immediately if you encounter any of the symptoms above. Additionally, inform your doctor promptly if you experience these symptoms after stopping the treatment.

Wellbutrin Seizure Warning Signs

Wellbutrin Seizure Warning Signs

While seizures are a rare side effect of Wellbutrin for anxiety, it’s essential to be aware of warning signs. These may include unusual changes in mood or behavior, such as agitation, hostility, or intense anxiety; a sudden increase in energy; or unusual movements of the eyes or tongue.

If any of these signs are observed, seeking medical attention promptly is crucial, as seizures can be a severe but uncommon side effect of Wellbutrin.


Wellbutrin Interactions

Interactions between drugs can alter the effectiveness of your medications or increase the risk of severe side effects. This document may not encompass all conceivable drug interactions. Therefore, it is vital to maintain a comprehensive list of all the products you are using, including prescription and non-prescription medications and herbal supplements. Share this list with your doctor and pharmacist, and avoid initiating, discontinuing, or altering the dosage of any medicines without the explicit approval of your doctor.

Certain products that may interact with this medication comprise codeine, pimozide, tamoxifen, and thioridazine.

Combining MAO inhibitors with this medication can lead to a severe, potentially fatal drug interaction. Refrain from using MAO inhibitors (including isocarboxazid, linezolid, metaxalone, methylene blue, moclobemide, phenelzine, procarbazine, rasagiline, safinamide, selegiline, tranylcypromine) while undergoing treatment with this medication. In addition, most MAO inhibitors should not be taken for two weeks before or after using this medication. Consult your doctor regarding the appropriate timing for starting or ceasing this medication about MAO inhibitors.

This medication may interfere with specific medical or laboratory tests, such as brain scans for Parkinson’s disease or urine screenings for amphetamines, potentially generating inaccurate test results. Both lab personnel and your healthcare providers must be informed of your use of this drug.


Can You Overdose On Wellbutrin?

In the event of an overdose with severe symptoms such as loss of consciousness or breathing difficulties, dial 911 immediately. If the situation is not as critical, promptly contact a poison control center.

The prescription drug is available in tablet form, including a sustained-release tablet (Wellbutrin SR) and an extended-release tablet (Wellbutrin XL). Wellbutrin is distinct from other common antidepressants. Its unique mechanism of action among antidepressants is thought to be due to the reuptake of dopamine and norepinephrine.

Bupropion may be an effective antidepressant across a broad spectrum of depressive conditions. It is a safe and effective medication for treating depression in the elderly. In addition to having a favorable side effect profile, bupropion has been shown to have positive results in treating anxiety associated with depression compared with sertraline and fluoxetine.

Wellbutrin Overdose Symptoms

An overdose of Wellbutrin can lead to symptoms like seizures, hallucinations, rapid heart rate, and loss of consciousness. If you suspect an overdose or observe these symptoms, seek immediate medical attention. It’s important never to exceed the prescribed dosage and to contact emergency services if an overdose is suspected.


Wellbutrin for Anxiety Drug Imprints

Wellbutrin DosageImprint on PillAnxiety Treatment
75 mg“WELLBUTRIN 75”A higher dosage is used in some instances, carefully monitored for anxiety relief.
150 mg“WELLBUTRIN 150”Often prescribed for anxiety disorders alongside depression.
300 mg“WELLBUTRIN 300”A higher dosage is used in certain cases, carefully monitored for anxiety relief.
Remember that this is a simplified representation, and actual prescriptions may vary. Always follow your healthcare provider’s guidance and never alter your Wellbutrin for anxiety dosage without consulting them.

Positive Wellbutrin for Anxiety Reviews

Individual responses to medication can vary, and it’s essential to consult with a healthcare professional for personalized advice and monitoring. However, here are some of the most common Wellbutrin for anxiety reviews.

  • “Wellbutrin has been a lifesaver for my anxiety. I’ve experienced a noticeable reduction in both generalized anxiety and panic attacks. The best part is that I haven’t felt any major side effects. It’s given me the mental clarity and stability I needed.”
  • “I hesitated to try Wellbutrin, but it’s been a game-changer. My anxiety used to be paralyzing, and now I feel much more in control. The energy boost is a welcome bonus, and I’ve found it to be a great fit for my overall mental health.”
  • “I’ve struggled with anxiety for years, and Wellbutrin has been my most effective medication. It didn’t just lift my mood; it also significantly reduced the constant worry and tension. It’s been a relief to find something that works finally.”

Negative Wellbutrin Reviews for Anxiety

  • “Wellbutrin worsened my anxiety symptoms. The initial period was challenging, with increased restlessness and constant jitteriness. It didn’t provide the relief I hoped for, and the side effects were difficult to tolerate. I eventually had to switch to a different medication.”
  • “I experienced heightened anxiety on Wellbutrin, especially during the first few weeks. The restlessness and racing thoughts became overwhelming. Despite giving it time, the negative impact on my anxiety persisted, and I had to explore other options.”
  • “Wellbutrin was not the right fit for my anxiety. The energy boost was too much for me, leading to increased nervousness. It didn’t provide the calming effect I needed; the side effects outweighed any potential benefits. My doctor and I decided to try a different approach to manage my anxiety.”

Do you have questions about anxiety and Wellbutrin or treatment in general? Call our helpline 24/7.

Can Wellbutrin Be Used for Anxiety?

Although Wellbutrin (bupropion) is often prescribed for treating anxiety, the drug’s efficacy varies from patient to patient. Wellbutrin may be prescribed for anxiety by some doctors even though the FDA has not formally approved it for this use.

Wellbutrin’s mechanism of action involves influencing mood-related neurotransmitters like norepinephrine and dopamine. Some people may find that their anxiety symptoms lessen due to this. However, people have widely varying reactions to Wellbutrin’s anti-anxiety effects.

Can Wellbutrin Cause Anxiety?

Although Wellbutrin (bupropion) is typically prescribed for depression, it may also be used to treat anxiety in some cases. Wellbutrin’s effect on anxiety in some users may be beneficial, while in others, it may increase.

Keep in mind that everyone reacts differently to medications. Anxiety may be reduced indirectly by a general uptick in one’s disposition, which may occur in some people. But for some, this could mean increased agitation, nervousness, or anxiety.

Talk to your doctor if you’re thinking about taking Wellbutrin causing anxiety or already taking it and experiencing increased anxiety. They will evaluate your symptoms, make dosage adjustments as necessary, and possibly recommend other treatments. Wellbutrin’s effectiveness in treating anxiety may be enhanced when used in conjunction with other therapies. Never alter your treatment plan without first speaking with your doctor.

Most Common Wellbutrin Side Effects

Here are some examples of side effects commonly reported with Wellbutrin SR and Wellbutrin XL treatment:

  • Headache.
  • Dry mouth.
  • Nausea.
  • Constipation.
  • Insomnia (trouble falling asleep or staying asleep).

What to take with Wellbutrin for anxiety?

What to take with Wellbutrin for anxiety? Managing anxiety often involves a comprehensive approach that includes lifestyle factors. Here’s a more holistic list:


  • SSRIs or SNRIs: Complementary antidepressants that can work alongside Wellbutrin to address anxiety.
  • Buspirone: An anxiolytic medicine that may be prescribed in combination with Wellbutrin.

Lifestyle and Behavioral Strategies:

  • Regular Exercise: Regular physical activity, such as aerobic exercise, has been shown to affect mood positively and can help reduce anxiety.
  • Therapy/Counseling: Cognitive-behavioral therapy (CBT) or other forms of psychotherapy can provide coping strategies and support in managing anxiety.
  • Mindfulness and Relaxation Techniques: Meditation, deep breathing, and progressive muscle relaxation can help alleviate anxiety symptoms.
  • Adequate Sleep: Ensuring a regular sleep pattern and sufficient sleep duration is crucial for mental health.
  • Healthy Diet: Eating a balanced and nutritious diet can contribute to overall well-being, impacting physical and mental health.
  • Limiting Caffeine and Stimulants: Excessive caffeine intake can contribute to anxiety, so moderating consumption may be beneficial.
  • Social Support: Maintaining solid social connections and seeking support from friends and family can be crucial in managing anxiety.

Natural Supplements:

  • Omega-3 Fatty Acids: In fish oil, omega-3 fatty acids may have mood-stabilizing properties.
  • Valerian Root or Passionflower: Some herbal supplements, under the guidance of a healthcare provider, might offer mild calming effects.

Medications like Wellbutrin help anxiety. But remember, the effectiveness of these strategies can vary from person to person. Working closely with a healthcare professional to tailor a comprehensive plan that suits your needs and circumstances is essential.

How can I determine if Wellbutrin is the right choice for me?

To assess if Wellbutrin is suitable for you, it’s essential to consult with a healthcare professional. They can evaluate your medical history, discuss your symptoms, and consider potential interactions with other medications to determine if Wellbutrin aligns with your specific needs and health profile.

Does Wellbutrin help with anxiety? Wellbutrin for anxiety, an atypical antidepressant, affects neurotransmitters in the brain, such as norepinephrine and dopamine. It is commonly prescribed to alleviate symptoms of depression, and in some cases, it may also be used off-label for anxiety disorders.
Does Wellbutrin help with anxiety? Wellbutrin for anxiety, an atypical antidepressant, affects neurotransmitters in the brain, such as norepinephrine and dopamine. It is commonly prescribed to alleviate symptoms of depression, and in some cases, it may also be used off-label for anxiety disorders.

Learn More:

How does Wellbutrin for anxiety work?

Wellbutrin, or bupropion, works for anxiety by affecting neurotransmitters in the brain, particularly norepinephrine and dopamine. These chemicals play a role in mood regulation and are thought to contribute to anxiety symptoms.

Wellbutrin’s unique mechanism of action differentiates it from other antidepressants, and its impact on these neurotransmitters is believed to alleviate anxiety symptoms in specific individuals.

Differenced Between Wellbutrin, Wellbutrin SR, and Wellbutrin XL Chart

Here’s a chart highlighting critical differences between Wellbutrin, Wellbutrin SR (sustained-release), and Wellbutrin XL (extended-release):

AspectWellbutrinWellbutrin SRWellbutrin XL
Release FormImmediate-ReleaseSustained-ReleaseExtended-Release
Dosage FrequencyTypically 2-3 times a dayUsually taken twice a dayWellbutrin XL dosage for anxiety can be taken once a day.
Dosage TimingMultiple times throughout the dayMorning and afternoonIt can be effective for anxiety
Duration of ActionShorter durationIntermediate durationWellbutrin XL for anxiety has a longer duration.
Common Dosages75 mg, 100 mg, 150 mg100 mg, 150 mg, 200 mg150 mg, 300 mg
Use for AnxietyIt may help with anxiety symptomsMay help with anxiety symptomsSimilar efficacy in anxiety treatment
Side EffectsSimilar side effects across formsSide effects can vary; often milderSide effects may be milder due to XR
This is a general overview, and individual responses may vary. Always follow the specific guidance provided by your healthcare professional and medication packaging.

Signs Wellbutrin is Working for Anxiety

Signs that Wellbutrin is effectively addressing anxiety may include:

  • Reduced Anxiety Symptoms: A noticeable decrease in the frequency and intensity of anxiety symptoms, such as excessive worry, restlessness, or irritability.
  • Improved Mood: Wellbutrin’s antidepressant effects may contribute to an overall improvement in mood, making you feel more positive and balanced.
  • Enhanced Energy Levels: Wellbutrin’s stimulating properties might increase energy and motivation, helping counter feelings of lethargy associated with anxiety.
  • Better Concentration: Some individuals report improved concentration and focus, which can benefit those whose anxiety affects cognitive function.
  • Stable Sleep Patterns: Wellbutrin can positively impact sleep for some individuals, leading to better sleep quality and a more regulated sleep pattern.
  • Functional Improvement: As anxiety symptoms decrease, you may notice improved daily functioning, including better performance at work or in personal relationships.

It’s essential to communicate regularly with your healthcare provider during the initial phases of taking Wellbutrin to monitor your response to the medication and make any necessary adjustments.

Wellbutrin and Lexapro Together for Anxiety

Lexapro and Wellbutrin combo for anxiety, which are from different antidepressant classes, is a common strategy to address anxiety and depression.

Wellbutrin’s energizing effects and Lexapro’s mood-stabilizing properties can complement each other, providing a more comprehensive approach to managing symptoms. However, a healthcare professional should carefully prescribe and monitor this combination to ensure effectiveness and minimize potential Wellbutrin for anxiety and Lexapro side effects.

Wellbutrin and Prozac Together for Anxiety

Using Wellbutrin and Prozac together can be an effective combination for treating anxiety and depression. Wellbutrin’s unique mechanism, which involves dopamine and norepinephrine, can complement Prozac’s action on serotonin. However, a healthcare professional should only initiate and monitor this combination to ensure safety, as drug interactions and individual responses may vary.

Wellbutrin vs Zoloft for Anxiety

Wellbutrin and Zoloft are distinct antidepressants with different mechanisms of action. Wellbutrin, an atypical antidepressant, primarily influences dopamine and norepinephrine, while Zoloft, an SSRI, increases serotonin levels. A healthcare professional should guide the choice between the two based on individual factors, as their efficacy and side effect profiles can vary.

Wellbutrin vs Lexapro for Anxiety

Lexapro vs Wellbutrin for anxiety? Here’s a simplified table comparing Wellbutrin and Lexapro for anxiety:

Class of MedicationAtypical AntidepressantSelective Serotonin Reuptake Inhibitor (SSRI)
Mechanism of ActionAffects dopamine and norepinephrineIncreases serotonin levels
Efficacy for AnxietyEffective for some types of anxietyGenerally effective for anxiety disorders
Side EffectsMay include restlessness, insomnia, weight lossCommon side effects include nausea, drowsiness, and sexual dysfunction
Stimulation vs SedationIt can be stimulating; it may increase energyCan be stimulating; it may increase energy
Typical Dosage Range75 mg to 300 mg per day10 mg to 20 mg per day
Administration FrequencyOnce or twice dailyOnce daily, usually in the morning
Potential InteractionsLimited interactions with other medicationsMay have more drug interactions; caution needed with certain medications
Response TimeEffects may be felt relatively quicklyFull therapeutic effects may take several weeks
Remember, individual responses to medications can vary, and the choice between Wellbutrin and Lexapro should be based on a thorough evaluation by a healthcare professional considering the individual’s health, history, and symptoms.

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Withdrawal symptoms caused by Wellbutrin for anxiety happen when a person who has become dependent on the medication suddenly stops using it. For a medically-assisted Wellbutrin detox, contact We Level Up New Jersey now.
Withdrawal symptoms caused by Wellbutrin for anxiety happen when a person who has become dependent on the medication suddenly stops using it. For a medically-assisted Wellbutrin detox, contact We Level Up New Jersey now.

Wellbutrin Withdrawal 

Discontinuing Wellbutrin for anxiety requires the advice of a doctor and should never be stopped abruptly. A gradual decrease is necessary to avoid withdrawal symptoms. Over 50 withdrawal symptoms associated with Wellbutrin have been reported. They range in severity from mild annoyances to life-threatening conditions and generally require monitoring by a medical professional.

Physical Withdrawal Symptoms

Physical withdrawal symptoms include the following:

  • Difficulties maintaining balance.
  • Lack of coordination.
  • Increased headaches or migraines.
  • Electric shock-like or tingling sensations.
  • General lethargy and fatigue.

These physical symptoms may signal a more severe condition that needs medical intervention.

Psychological Withdrawal Symptoms

Wellbutrin withdrawal may trigger psychological symptoms that are out of character for the user. Aggressive behavior that is not characteristic of the person taking the medication, irritability, hostility, and paranoia may occur. Anxiety, troubling thoughts, and worsening depression that circumstances cannot explain should be reported to the doctor. 

Highly emotional states, overreaction to everyday situations, depersonalization, and severe internal restlessness happen for some individuals. Crying spells and nervousness may surface for no apparent reason. Notify your physician immediately if you experience psychological disturbances that are not characteristic of you or have suicidal thoughts.

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Wellbutrin for Anxiety and Depression Facts

Wellbutrin Overview

Wellbutrin, known by its generic name, bupropion, is a prescription medication primarily used to treat depression. It belongs to the class of drugs known as atypical antidepressants. While its primary indication is depression, it is sometimes prescribed off-label for other conditions, such as anxiety and smoking cessation.

Wellbutrin for Anxiety Mechanism of Action

Wellbutrin works by affecting the levels of neurotransmitters in the brain, particularly norepinephrine and dopamine. It inhibits the reuptake of these neurotransmitters, leading to increased levels in the brain and potentially improving mood and other mental health symptoms.

Wellbutrin Uses

  • Treatment of major depressive disorder.
  • Seasonal affective disorder (SAD).
  • Smoking cessation aid.
  • Off-label use for anxiety, attention deficit hyperactivity disorder (ADHD), and other conditions.

Dosage: Dosage can vary based on the specific condition being treated, individual response, and medical history. It’s essential to follow the prescribed dosage and any recommendations from your healthcare provider.

Wellbutrin Side Effects

Common side effects of Wellbutrin may include:

  • Nausea.
  • Headache.
  • Dry mouth.
  • Insomnia.
  • Agitation.
  • Increased heart rate.
  • Weight loss.
  • Constipation.

Wellbutrin for Anxiety Precautions

  • Inform your doctor of any existing medical conditions or medications you are taking.
  • Do not take Wellbutrin if you have a history of seizures or eating disorders or are undergoing abrupt alcohol or sedative withdrawal.
  • Monitor for changes in mood or behavior, especially during the initial stages of treatment.


Medications like MAOIs, SSRIs, and antipsychotics may not work as well with Wellbutrin because of the potential for interactions. Tell your healthcare provider about any supplements and medications you’re currently using.

Wellbutrin Withdrawal: Discontinuing Wellbutrin should be done under medical supervision to minimize withdrawal symptoms, including mood swings, irritability, and flu-like symptoms.

Important Notes

  • Wellbutrin may take several weeks to start showing its full effects.
  • Avoid alcohol while taking Wellbutrin, as it can increase the risk of seizures.
  • Do not stop taking Wellbutrin abruptly without consulting your doctor.

Always consult a healthcare professional before starting or discontinuing any medication. This fact sheet provides general information and is not a substitute for medical advice.

Wellbutrin Side Effects Long Term

Long-term use of Wellbutrin may, for some individuals, lead to side effects. These can vary, but commonly reported issues include changes in weight, sleep disturbances, and potential impacts on sexual function. Always communicate with your healthcare provider about any concerns or persistent side effects.

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45.8% of American adults used a prescription drug – legally or not – within the past 30 days. Healthcare specialists generally agree that a high use rate and availability drive reported rates of prescription drug abuse, addiction, and overdose.

16.3 million

People misuse prescriptions a year.

Source: NIDA


People or 11.9% of people who misuse prescriptions are definitively addicted to the prescription drugs they misuse.

Source: NIDA


Prescription drug abusers constitute 5.76% of Americans over the age of 12.

Source: NIDA

Why is Wellbutrin Prescribed? 

The U.S. Food and Drugs Administration (FDA) approved uses for Wellbutrin include major depressive disorder (MDD) and seasonal depressive disorder (SAD.) The symptoms of these disorders include the following.

Major Depressive Disorder (MDD)

Individuals with major depression have several of these symptoms for at least two weeks:

  • Depressed mood – feeling sad, empty, or tearful.
  • Loss of interest or pleasure in your usual activities.
  • Feeling worthless, guilty, hopeless, and helpless.
  • Sleep and eat more or less than expected (for most people, it is less).
  • Low energy, trouble concentrating, or thoughts of death (suicidal thinking).
  • Psychomotor retardation (feeling like you are moving and thinking in slow motion).
  • Psychomotor agitation (‘nervous energy’).
  • Suicidal thoughts or behaviors.

Seasonal Depressive Disorder (SAD)

A major depressive episode with the same symptoms as MDD also consistently recurs at particular times during the year, usually during the dark winter months.  

Wellbutrin for ADHD and Anxiety and other Off-Label Prescriptions

Wellbutrin is sometimes used off-label (using an FDA-approved drug for unapproved use to treat a medical condition) for the following conditions:

  • Attention deficit hyperactivity disorder (ADHD).
  • Depression in bipolar disorder.
  • Obesity.
  • Sexual dysfunction due to SSRI antidepressants.

Your mental health provider should justify their thinking in recommending an “off-label” Wellbutrin for anxiety and adhd treatment. They should be clear about the research limits around that medication and if there are any other options. Wellbutrin for anxiety and weight loss still needs further research to prove its effectiveness.

Does Wellbutrin Work for Anxiety?

Does Wellbutrin cause anxiety? Medications can affect individuals in different and more ways than one. As such, Wellbutrin has been linked to anxiety in some cases. But while it can cause anxiety in some individuals, it is an effective treatment for anxiety disorders in others. Some test subjects developed anxiety-related side effects in clinical trials shortly after taking Wellbutrin. It was also noted that these effects are exacerbated in the period following a dosage increase. These Wellbutrin anxiety-related side effects include:

  • Anxiety.
  • Insomnia.
  • Restlessness and agitation.

According to the FDA, up to 2% of the people who experienced these side effects discontinued their medication use. For some subjects, these side effects were so severe that they required treatment with anti-anxiety medication and sedatives.

Wellbutrin Dosage for Depression and Anxiety

Wellbutrin (bupropion) for depression and anxiety comes in various formulations, each with its recommended starting dose. When treating depression, a starting dose of 150 mg once daily is typically recommended. Under the supervision of a medical professional, this can be increased to a maximum daily dose of 450 milligrams (mg).

Wellbutrin is not usually the first medication prescribed for anxiety. Off-label use for anxiety may involve a dose comparable to that used for depression. It’s important to talk to your doctor about any problems or side effects and follow their instructions carefully. Medication is safer and more effective when started and adjusted under medical supervision. Anxiety sufferers considering Wellbutrin should talk to their doctor about the drug’s benefits, risks, and other treatment options.

What to Pair with Wellbutrin for Anxiety

Pairing Wellbutrin with other medications for anxiety should always be done under the guidance and supervision of a healthcare professional. While Wellbutrin is not a first-line treatment for anxiety disorders, some doctors may consider combining it with other medications in some instances. Here are a few options that may be considered:

  • Selective Serotonin Reuptake Inhibitors (SSRIs): Wellbutrin works on different neurotransmitters than SSRIs. Combining Wellbutrin with SSRIs like sertraline or escitalopram may help address depression and anxiety symptoms.
  • Buspirone: Buspirone is an anti-anxiety medication that can be used with Wellbutrin. It has a different mechanism of action and can help manage anxiety symptoms without causing sedation or dependency.
  • Benzodiazepines (Short-Term): Benzodiazepines like lorazepam or clonazepam are potent anxiety-relief medications. They are typically used short-term and can be considered for acute anxiety episodes in combination with Wellbutrin.
  • Gabapentin or Pregabalin: These medications, originally developed to treat seizures, also manage anxiety. They can be considered combined with Wellbutrin, mainly if co-occurring anxiety and neuropathic pain symptoms exist.
  • Psychotherapy: Combining Wellbutrin with psychotherapy, such as cognitive-behavioral therapy (CBT), can effectively manage anxiety. Therapy provides coping strategies and tools to address underlying causes of anxiety.
  • Lifestyle Changes: Along with medication, lifestyle modifications such as regular exercise, proper sleep, stress management techniques, and a balanced diet can play a significant role in reducing anxiety symptoms.

It’s crucial to discuss your individual needs, medical history, and preferences with your healthcare provider to determine the best course of treatment. Medication combinations should only be prescribed and adjusted by a qualified medical professional to ensure safety and effectiveness.

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To determine the most effective ways to treat long term Wellbutrin side effects or when Wellbutrin making anxiety worse, especially if it is mixed with alcohol, it’s crucial first to get an accurate assessment of all the symptoms.

When a mental health professional has evaluated the symptoms, it may be determined that another form of depression is present and needs a particular type of treatment. Very often, some combination of psychotherapy, medication, and lifestyle changes are effective for coping with functional.

Never attempt to detox from Wellbutrin for anxiety or any other medication without consulting your healthcare provider. Contact We Level Up NJ today for detox guidance.
Never attempt to detox from Wellbutrin for anxiety or any other medication without consulting your healthcare provider. Contact We Level Up NJ today for detox guidance.

Detoxification from Wellbutrin should always be done under the supervision and guidance of a healthcare professional. Abruptly stopping Wellbutrin can lead to withdrawal symptoms, including mood changes, irritability, and even physical symptoms like headaches or nausea. Your healthcare provider will create a tapering plan, gradually reducing the dosage to help minimize withdrawal effects and ensure a smooth transition.

Medically-Assisted Detox

Detox is often considered the first stage of treatment. It will help you navigate Wellbutrin withdrawal but doesn’t address patterns of thought and behavior contributing to Wellbutrin use. Various treatment approaches and settings can help provide the ongoing support necessary to maintain long-term sobriety after you complete detox.

Cravings are very common during detox and can be challenging to overcome. This often leads to relapse. Constant medical care provided during inpatient treatment helps prevent relapse. Clinicians can offer the necessary medication and medical expertise to lessen cravings and the effects of alcohol withdrawals.

Wellbutrin Anxiety Treatment

Combining prescriptions for anxiety with psychotherapy can be a practical approach to managing stress. Here’s a simplified list of psychotherapy options that may complement Wellbutrin:

  • Cognitive-behavioral therapy (CBT): Focuses on identifying and changing negative thought patterns and behaviors contributing to anxiety.
  • Mindfulness-Based Cognitive Therapy (MBCT): Integrates mindfulness practices with traditional CBT to help individuals become more aware of their thoughts and feelings.
  • Dialectical Behavior Therapy (DBT): Emphasizes skills training to manage emotions and improve interpersonal effectiveness, particularly helpful for individuals with intense emotional experiences.
  • Exposure Therapy: Gradual exposure to anxiety triggers in a controlled environment, helping individuals confront and overcome fears.
  • Interpersonal Therapy (IPT): Targets interpersonal issues that contribute to anxiety and helps improve communication and relationship skills.
  • Psychodynamic Therapy: Explores unconscious processes and past experiences to gain insight into current emotional struggles.
  • Acceptance and Commitment Therapy (ACT): Focuses on accepting one’s thoughts and feelings while committing to actions aligned with personal values.

The effectiveness of psychotherapy varies from person to person. It’s essential to discuss with your mental health professional to determine the most suitable approach for your individual needs.

Dual Diagnosis Treatment

Prescription drug dependency and mental health disorders often co-occur. Traumatic experiences can often result in a mental health disorder and drug dependence. Dual-diagnosis rehabilitation treats both of these issues together. The best approach for the treatment of dual diagnosis is an integrated system. This strategy treats both the drug problem and the mental disorder simultaneously. Regardless of which diagnosis (mental health or drug problem) came first, long-term recovery will depend mainly on the treatment for both disorders done by the same team or provider.

Wellbutrin Detox. Find the Support You Need.

Withdrawal from Wellbutrin is often a challenging process to go through alone. Many people experience relapses during withdrawal in an attempt to alleviate symptoms and satisfy cravings. However, you can manage withdrawal symptoms and successfully recover with detox and rehab therapy and a robust support system at the We Level Up New Jersey treatment center. If you require assistance with your rehab journey, contact a We Level Up NJ treatment professional now. Your call is free and confidential.

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Top 20 Most Common FAQs About Wellbutrin for Anxiety

  1. What to pair with Wellbutrin for anxiety?

    Pairing Wellbutrin for anxiety with psychotherapy, such as cognitive-behavioral therapy (CBT), can enhance the overall effectiveness in managing symptoms, providing a holistic approach to treatment. Also, lifestyle modifications like regular exercise and stress reduction techniques can complement the effects of Wellbutrin for depression and anxiety.

  2. Is Wellbutrin good for anxiety?

    Wellbutrin positive effects can be sufficient for some individuals in managing anxiety symptoms, especially when traditional anti-anxiety medications are unsuitable or have not produced the desired results. However, individual responses vary, and it’s crucial to consult with a healthcare professional to determine the most suitable treatment plan based on specific needs and circumstances.

  3. How long does Wellbutrin take to work for anxiety?

    Wellbutrin for anxiety dosage may take a few weeks to show noticeable improvements in symptoms as the medication gradually influences neurotransmitter levels in the brain. Patience is vital, and adhering to the prescribed Wellbutrin XL dosage for depression and anxiety while closely monitoring any changes in consultation with your healthcare provider is essential.

  4. How do you feel on Wellbutrin?

    Individuals on Wellbutrin dosage for depression and anxiety often report improved mood and increased energy, although side effects can vary. Responses to medications like Wellbutrin for anxiety are subjective, and consulting with a healthcare professional is crucial for personalized guidance.

  5. Does Wellbutrin make anxiety worse?

    While rare, some individuals may initially experience increased anxiety when starting Wellbutrin. This typically subsides as the body adjusts to the Wellbutrin dosage for anxiety, but any concerns should be promptly discussed with a healthcare provider.

  6. Can Wellbutrin cause anxiety?

    Wellbutrin for anxiety is generally considered to have a lower risk of causing anxiety than other antidepressants. However, individual responses vary, and if you experience increased stress or any concerning Wellbutrin side effects anxiety responses, it’s essential to communicate with your healthcare provider for possible adjustments to the treatment plan.

  7. Does Wellbutrin make you cry?

    Wellbutrin and crying are not typically associated. Some reports about crying on Wellbutrin included patients crying “for no reason” several times a day. Some described that the Wellbutrin crying spells last several seconds and cannot be resisted. However, individual reactions to medications can vary, and any unexpected emotional changes should be discussed with a healthcare professional to determine the appropriate course of action.

  8. Is Wellbutrin for anxiety or depression?

    Wellbutrin is primarily prescribed as an antidepressant, but it is sometimes used off-label to address anxiety disorders. Its effectiveness in managing depression and anxiety can vary among individuals, and decisions regarding its use should be made in consultation with a healthcare provider.

  9. Can you stop Wellbutrin abruptly?

    Abruptly stopping Wellbutrin for anxiety can lead to withdrawal symptoms, and it’s not recommended. If you and your healthcare provider decide to discontinue the medication, a gradual tapering-off approach is typically advised to minimize potential side effects.

  10. Is Wellbutrin a benzo?

    No, Wellbutrin for anxiety and depression is not a benzodiazepine (benzo). It’s an atypical antidepressant that works on neurotransmitters in the brain, specifically norepinephrine and dopamine.

  11. How do you spell Wellbutrin?

    Wellbutrin for anxiety is spelled W-E-L-L-B-U-T-R-I-N. It’s essential to use the correct spelling when discussing or searching for information about the medication.

  12. Does Wellbutrin increase anxiety?

    While Wellbutrin for anxiety is generally considered to have a lower risk of causing anxiety than other antidepressants, individual responses can vary. Some people may experience increased anxiety initially, but this often subsides as the body adjusts to the medication. If you have concerns about anxiety while taking Wellbutrin, it’s crucial to consult your healthcare provider for guidance.

  13. What does Wellbutrin do to you?

    Wellbutrin for anxiety, an atypical antidepressant, affects neurotransmitters in the brain, such as norepinephrine and dopamine. It is commonly prescribed to alleviate symptoms of depression, and in some cases, it may also be used off-label for anxiety disorders.

  14. Does Wellbutrin irritability go away?

    In many cases, irritability as a side effect of Wellbutrin for anxiety tends to diminish as the body adjusts to the medication. However, if it persists or becomes bothersome, discussing Wellbutrin and irritability with your healthcare provider is vital to determine the best course of action, which may involve adjusting the dosage or considering alternative treatments.

  15. Can I drink alcohol while taking Wellbutrin?

    It’s advisable to consult your healthcare provider regarding alcohol consumption while taking Wellbutrin for anxiety, as the combination may increase the risk of seizures. Your doctor can provide personalized guidance based on your health status and individual factors.

  16. Can Wellbutrin be used for social anxiety disorder?

    While Wellbutrin is not typically the first-line treatment for social anxiety disorder, it may be considered when other medications are unsuitable or ineffective. Consultation with a mental health professional is crucial to determine the most appropriate treatment plan when considering Wellbutrin for social anxiety.

  17. Are there common side effects of Wellbutrin for anxiety?

    Common side effects of Wellbutrin can include insomnia, dry mouth, and nausea. However, individual responses vary, and it’s essential to communicate any concerns or unexpected side effects with your healthcare provider.

  18. Can Wellbutrin be used alongside other anxiety medications?

    Combining Wellbutrin with other anxiety medications should be done under the supervision and guidance of a healthcare professional, as there may be potential interactions. Your doctor can assess your situation and determine the best Wellbutrin combo for anxiety and a safe treatment plan for anxiety management.

  19. Is Wellbutrin addictive?

    Wellbutrin for anxiety and depression is not considered addictive in the way substances like benzodiazepines can be. However, sudden discontinuation should be avoided to prevent potential withdrawal symptoms, and any changes to the medication should be discussed with a healthcare professional.

  20. Can Wellbutrin be used for generalized anxiety disorder (GAD)?

    Wellbutrin is not typically the first-line treatment for generalized anxiety disorder (GAD), as it primarily targets depression and may not be as effective for anxiety. Your healthcare provider can guide you on the most suitable treatment options for GAD based on your needs.

Learn About Anxiety Disorder Facts and Anxiety Treatment Programs That Can Help You

While Wellbutrin for anxiety may relieve some signs and symptoms, a comprehensive approach often involves combining medication with therapeutic interventions such as cognitive-behavioral therapy (CBT). CBT can equip individuals with coping strategies and tools to effectively manage anxious thoughts and behaviors. Also, lifestyle changes like regular exercise, adequate sleep, and stress management techniques can contribute to a more holistic and sustainable anxiety management plan.

Do you have questions about the alternatives to Wellbutrin for anxiety or withdrawal treatment in general? Call our helpline 24/7.

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Is Wellbutrin for Anxiety? Video

Beyond its primary role in combating depression, Wellbutrin has demonstrated effectiveness in managing specific anxiety disorders. Unlike conventional antidepressants, Wellbutrin uniquely targets neurotransmitters like norepinephrine and dopamine, making it a viable option for individuals grappling with both depression and anxiety.

Discover the diverse applications of Wellbutrin in treating depression and how it seeks to restore balance to natural brain chemicals. Learn about the optimal timing for taking Wellbutrin and practical tips for minimizing potential sleep disturbances, a common concern among users.
Search We Level Up NJ Wellbutrin for Anxiety, Mental Health, Detox Topics & Resources

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