What’s the Difference Between CBD and THC? CBD vs THC Benefits, Differences, and Effects

Difference Between CBD and THC. The two most well-known cannabinoids, cannabidiol (CBD) and tetrahydrocannabinol (THC) are found in the cannabis plant. They have similar molecular structures but different physiological and psychological effects.


CBD (cannabidiol) and THC (tetrahydrocannabinol), two of the most well-known cannabinoids derived from the cannabis plant, have attracted a lot of interest due to the possible therapeutic effects they may have. Both compounds interact with the body’s endocannabinoid system but do so in different ways and serve different purposes. CBD’s non-psychoactive nature and potential sedative effects have made it a popular treatment option for various medical issues. The difference between CBD and THC can be multi-faceted and will be discussed further.

However, THC gets most of the credit for the euphoric “high” associated with cannabis use due to its psychoactive properties. Knowledge of their differences is essential to make educated decisions about the medical or recreational use of CBD and THC. To aid you in navigating the complex world of cannabinoids, this article delves into the specific qualities, benefits, and potential drawbacks of CBD and THC.

What’s the Difference Between CBD and THC?

THC (tetrahydrocannabinol) and CBD (cannabidiol) are two of the most well-known cannabinoids found in cannabis. Although they are both cannabinoids, they are differentiated from one another by their unique characteristics and effects.

CBD’s potential therapeutic applications have piqued interest even though it is commonly regarded as non-intoxicating. Relaxation, decreased anxiety, and possibly anti-inflammatory effects are some of its health benefits. CBD’s rising profile has prompted the development of numerous CBD-based goods, including oils, capsules, skincare products, and even edibles.

However, THC is the active ingredient in cannabis that produces the intoxicating “high” the drug is known for. THC has medicinal potential beyond its psychoactive effects, including as a pain reliever and appetite booster.

THC vs CBD Comparison Table

The table comparing tetrahydrocannabinol (THC) and cannabidiol (CBD) provides a thorough overview of the key distinctions between these two of the most well-known cannabinoids in cannabis. This table explains their features, effects, and applications. The table helps people make educated decisions about their cannabis consumption by highlighting important factors like psychoactivity, medical benefits, legal considerations, usage, side effects, and interactions. Whether your interest in cannabis is medical (to treat a specific condition) or recreational (to have fun), this table will help you learn more about the differences between THC and CBD.

Comparing THC and CBD: Understanding the Differences in Effects, Medical Applications, and More.

Difference Between CBD and THC Facts


Cannabidiol (CBD) and Tetrahydrocannabinol (THC) are prominent cannabinoids in the cannabis plant. Despite sharing a similar molecular structure, they exhibit distinct effects on the body and mind.


CBD is non-psychoactive, ensuring it doesn’t induce the euphoric “high” often associated with cannabis. Conversely, THC is psychoactive and can lead to altered perception and a sense of euphoria.

Medical Applications

CBD boasts applications in anxiety reduction, pain management, and treatment of certain medical conditions. THC is useful for alleviating pain, boosting appetite, and minimizing nausea.


The legality of CBD and THC varies across regions. CBD enjoys wider acceptance and legality, often with specific regulations. THC’s psychoactive nature renders it more restricted in many jurisdictions.

Side Effects

CBD is generally well-tolerated and is linked to minimal side effects such as dry mouth or drowsiness. In contrast, THC can lead to cognitive changes, memory impairment, and heightened anxiety in some individuals.

CBD with THC Drug Testing

CBD consumption is less likely to result in positive drug tests, whereas THC consumption may lead to detectable results on screenings.

Interaction with Receptors

CBD’s interaction with CB1 receptors is weaker or indirect, resulting in fewer psychotropic effects. In contrast, THC strongly binds with CB1 receptors, contributing to its pronounced psychoactive impact.

Health Benefits

CBD is believed to possess anti-inflammatory and neuroprotective properties, potentially offering therapeutic benefits for various conditions. THC’s potential lies in pain relief, relaxation, and mood elevation.


CBD comes in diverse forms, including oils, capsules, edibles, and topical applications. THC is commonly found in smokable flowers, edibles, concentrates, and other extracts.

Usage Considerations

Consult healthcare professionals before using CBD or THC for medical purposes. Understanding local laws and regulations is vital, as they influence the legality and availability of these cannabinoids.

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Difference Between CBD and THC Statistics

CBD is becoming increasingly popular due to its potential health benefits, while THC use is becoming more mainstream. Over a third of U.S. adults have tried CBD products for health benefits in the last few years. Meanwhile, many states have legalized recreational use of THC due to its widespread acceptance. Sixty-four percent of CBD users use it for pain relief, while tetrahydrocannabinol’s (THC’s) psychoactive effects are linked to changes in perception and cognition.

CBD has gained much popularity because it has no psychoactive effects and may help with anxiety. However, about 9 percent of chronic THC users eventually become dependent. CBD’s therapeutic potential has led to a significant increase in scientific studies and clinical trials over the past decade, but both compounds are under extensive research scrutiny despite these differences.


In recent years, CBD has gained significant popularity, with over 33% of adults in the United States having tried CBD products for various health and wellness purposes.

Source: CDC


Approximately 64% of CBD users reported using CBD products to manage pain, making it one of the most common reasons for CBD consumption.

Source: NIH


THC’s ability to stimulate appetite (the “munchies”) has been documented in multiple studies, with around 40% of THC users experiencing an increased desire to eat.

Source: NIH

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CBD vs THC For Anxiety

The effects of cannabidiol (CBD) and tetrahydrocannabinol (THC) on anxiety have received much attention recently. Both compounds interact with the endocannabinoid system but have different effects on anxiety.

The anti-anxiety effects of CBD (cannabidiol) are widely praised. It’s thought to calm the mind and body without producing the “high” associated with psychoactive THC. Based on its potential to interact with serotonin receptors and induce feelings of calm, CBD has been studied for its potential to alleviate anxiety.

However, tetrahydrocannabinol (THC) may produce opposite effects on anxiety in different people. At higher doses, THC can cause anxiety, paranoia, and even panic attacks in some users, even though many report feeling calm and happy after using it. These anxiety-inducing effects may be attributable, in part, to THC’s psychoactive properties.

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CBD vs. THC Side-Effects

CBD and THC, two significant cannabinoids, have benefits and drawbacks, but these can vary from person to person. Because it is not psychoactive, CBD (cannabidiol) is generally regarded as having fewer and milder side-effects than THC (tetrahydrocannabinol) because it is not psychoactive. CBD may cause mild drowsiness, dry mouth, and appetite and body weight alterations.

THC’s psychoactive properties can heighten the experience. Some users report euphoria, relaxation, and an enhanced sense of perception, while others report adverse effects like anxiety, paranoia, racing heart, clumsiness, and memory loss. Higher doses tend to have more substantial psychoactive effects.

Comparison of Side Effects Between CBD and THC: This table outlines the potential side effects associated with CBD and THC consumption, providing insights into their contrasting effects on various aspects of health and well-being.

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We Level Up NJ helps people detox in a caring and supportive environment with the resources they need to live healthier. Our detox program provides a safe, nurturing environment to focus on your health while removing CBD, THC, or both.
We Level Up NJ helps people detox in a caring and supportive environment with the resources they need to live healthier. Our detox program provides a safe, nurturing environment to focus on your health while removing CBD, THC, or both.

We Level Up NJ Detox CBD vs THC

To help people safely and effectively rid their bodies of the lingering effects of CBD and THC, We Level Up NJ provides a thorough detox program. The potential effects of cannabidiol (CBD) and tetrahydrocannabinol (THC) on the body and mind are considered in our individualized detox program.

Our CBD vs THC detox program is individualized to meet the specific requirements of each patient. Supporting the body’s detoxification mechanisms, our experienced medical professionals lead clients through a structured detox process. We employ evidence-based practices, nutritional guidance, hydration, and other therapeutic modalities to facilitate the detoxification procedure.

Our mission at We Level Up NJ is to help people through the detox process in a caring and supportive environment with all the resources they need to make the change toward a healthier lifestyle. Our detox program offers a safe and nurturing space to focus on your health while removing CBD, THC, or both from your system.

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  1. Does CBD oil with THC in it?

    CBD oil can contain varying levels of THC, depending on the source and the manufacturing process. Full-spectrum CBD oil, derived from the whole hemp plant, may contain trace amounts of THC, usually below 0.3%, as federal law allows. This minimal THC content cannot produce psychoactive effects but may still appear on sensitive drug tests.

    On the other hand, broad-spectrum CBD oil contains other cannabinoids and compounds found in the hemp plant, but it has the THC removed. As the name suggests, CBD isolate contains only CBD and no other cannabinoids or compounds, including THC.

  2. Do CBD gummies have THC?

    The amount of THC can vary depending on the gummy type and where it came from. CBD gummies can be made from the same extracts as CBD oil: full-spectrum, broad-spectrum, or CBD isolate.

    Full-spectrum CBD gummies are made from the whole hemp plant and may have minimal amounts of THC, usually less than 0.3%, the limit set by US federal law. Broad-spectrum CBD gummies, on the other hand, are made in a way that removes THC but keeps other cannabinoids and compounds that are good for you. CBD isolate gummies only have CBD, not THC or any other cannabinoids or compounds.

How to Sober up Fast from CBD vs THC Informative Video

In this helpful video, we provide practical tips on how to sober up quickly after consuming THC. Discover practical strategies to reduce the psychoactive effects of cannabis, including hydration, fresh air, and light physical activity. Learn about potential remedies to alleviate discomfort and regain clarity, allowing you to navigate daily activities more comfortably. Everyone’s response to THC varies, so these tips can serve as general guidelines to promote a more comfortable experience.

Search What’s the Difference Between CBD and THC? CBD vs THC Detox & Mental Health Topics & Resources
  1. National Institute on Drug Abuse (NIDA) – Marijuana: https://www.drugabuse.gov/drug-topics/marijuana
  2. National Highway Traffic Safety Administration (NHTSA) – Drugs and Human Performance Fact Sheets: https://www.nhtsa.gov/sites/nhtsa.dot.gov/files/documents/812440-drugsandhumanperformancefactshheet.pdf
  3. Drug Enforcement Administration (DEA) – Drugs of Abuse Resource Guide: https://www.dea.gov/sites/default/files/2022-12/2022_DOA_eBook_File_Final.pdf
  4. Centers for Disease Control and Prevention (CDC) – Marijuana and Public Health: https://www.cdc.gov/marijuana/index.htm
  5. National Conference of State Legislatures (NCSL) – Marijuana Overview: https://www.ncsl.org/research/civil-and-criminal-justice/marijuana-overview.aspx
  6. U.S. Food and Drug Administration (FDA) – Cannabis and Cannabis-Derived Products, Including Cannabidiol (CBD): https://www.fda.gov/news-events/public-health-focus/fda-regulation-cannabis-and-cannabis-derived-products-including-cannabidiol-cbd
  7. National Organization for the Reform of Marijuana Laws (NORML) – State Laws: https://norml.org/states